Preparation of Tannic Acid/Hyaluronic Acid Coating to Improve the Corrosion Resistance of Implant Material Based on AZ31B Magnesium Alloy

Magnesium (Mg) has good biocompatibility, making it suitable as an implant material. However, Mg has a high corrosion rate because of the reaction between magnesium implants and fluids in the human body. To lower the corrosion rate of magnesium alloys, it is necessary to perform a coating process using tannic acid (TA) and hyaluronic acid (HYA), as we have done in this study. TA, an active ingredient, is relatively inexpensive, easy to find, and can effectively reduce the degradation rate. SEM characterization showed that the TA-HYA layer was formed by chelation between the Mg and TA surfaces. Furthermore, adding HYA to the coating covered the cracks caused by the TA layer and increased the hydrophilic properties. In vitro corrosion tests using Tafel polarization showed that the TA-HYA coating reduced the corrosion rate of the magnesium alloy from 7.379 mm/year to 0.204 mm/year. The immersion test in the SBF solution showed that the TA-HYA layer could bind Mg2+, which is beneficial for new bone growth.

Automated summary

Magnesium has good biocompatibility but high corrosion rate. To reduce the corrosion rate, we coated the magnesium alloy with tannic acid (TA) and hyaluronic acid (HYA). The TA-HYA coating effectively reduced the corrosion rate and improved hydrophilic properties. In vitro tests showed that the coating could bind Mg2+ ions and promote new bone growth.