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An update on the development of novel antifungal agents for eumycetoma

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FRONTIERS IN PHARMACOLOGY
卷 14, 期 -, 页码 -

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FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2023.1165273

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eumycetoma; Neglected Tropical Disease (NTD); mycology; skin NTDs; Madurella mycetomatis

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Eumycetoma, a chronic subcutaneous mycosis, has limited treatment options and often requires extensive surgery. This article discusses the need for better treatments, current developments, and future challenges.
Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being used to develop and evaluate new treatments for eumycetoma, summarise the latest developments and discuss the challenges that lie ahead.

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