相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations
Robert R. Edwards et al.
JOURNAL OF PAIN (2023)
Gut enterochromaffin cells drive visceral pain and anxiety
James R. R. Bayrer et al.
NATURE (2023)
Ferroptosis in cancer therapy: a novel approach to reversing drug resistance
Chen Zhang et al.
MOLECULAR CANCER (2022)
PROTAC targeted protein degraders: the past is prologue
Miklos Bekes et al.
NATURE REVIEWS DRUG DISCOVERY (2022)
Innovations and advances in modelling and measuring pain in animals
Katelyn E. Sadler et al.
NATURE REVIEWS NEUROSCIENCE (2022)
Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis
Qian Hu et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)
Ferroptosis in cancer and cancer immunotherapy
Lei Zhao et al.
CANCER COMMUNICATIONS (2022)
Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer
Shane J. F. Cronin et al.
SCIENCE TRANSLATIONAL MEDICINE (2022)
Gut-Brain-Microbiota Axis: Antibiotics and Functional Gastrointestinal Disorders
Tarkan Karakan et al.
NUTRIENTS (2021)
Sulfasalazine alleviates neuropathic pain hypersensitivity in mice through inhibition of SGK-1 in the spinal cord
Sai Yasukochi et al.
BIOCHEMICAL PHARMACOLOGY (2021)
Is hyaluronic acid the perfect excipient for the pharmaceutical need?
Daniela Harrer et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)
Sulfasalazine, a potent suppressor of gastric cancer proliferation and metastasis by inhibition of xCT: Conventional drug in new use
Jinfu Zhuang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)
Molecular and metabolic bases of tetrahydrobiopterin (BH4) deficiencies
Nastassja Himmelreich et al.
MOLECULAR GENETICS AND METABOLISM (2021)
Sapropterin (BH4) Aggravates Autoimmune Encephalomyelitis in Mice
Katja Schmitz et al.
NEUROTHERAPEUTICS (2021)
Efficacy and Safety of Diclofenac-Hyaluronate Conjugate (Diclofenac Etalhyaluronate) for Knee Osteoarthritis: A Randomized Phase III Trial in Japan
Yoshihiro Nishida et al.
ARTHRITIS & RHEUMATOLOGY (2021)
Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice
Masahide Fujita et al.
ARTHRITIS & RHEUMATOLOGY (2020)
Virtual screening to identify potent sepiapterin reductase inhibitors
Hua Gao et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2020)
Aspirin and its pleiotropic application
Jolanta Hybiak et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2020)
GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
Vanessa A. N. Kraft et al.
ACS CENTRAL SCIENCE (2020)
Sepiapterin reductase promotes hepatocellular carcinoma progression via FoxO3a/Bim signaling in a nonenzymatic manner
Yao Wu et al.
CELL DEATH & DISEASE (2020)
Hyaluronic Acid-Based Theranostic Nanomedicines for Targeted Cancer Therapy
So Yun Lee et al.
CANCERS (2020)
Consensus guideline for the diagnosis and treatment of tetrahydrobiopterin (BH4) deficiencies
Thomas Opladen et al.
ORPHANET JOURNAL OF RARE DISEASES (2020)
Targeted protein degradation: current and future challenges
Alexander Hanzl et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2020)
Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity
Ananda Staats Pires et al.
FRONTIERS IN NEUROSCIENCE (2020)
Mechanisms Mediating High-Molecular-Weight Hyaluronan-Induced Antihyperalgesia
Ivan J. M. Bonet et al.
JOURNAL OF NEUROSCIENCE (2020)
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
Mariluz Soula et al.
NATURE CHEMICAL BIOLOGY (2020)
Systematic Investigation of the Permeability of Androgen Receptor PROTACs
Duncan E. Scott et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury
William Renthal et al.
NEURON (2020)
Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis
Nandini Verma et al.
SCIENCE ADVANCES (2020)
Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system
Maciej Salaga et al.
BIOCHEMICAL PHARMACOLOGY (2019)
A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain
Dustin P. Green et al.
NEURON (2019)
A chemical approach for global protein knockdown from mice to non-human primates
Xiuyun Sun et al.
CELL DISCOVERY (2019)
Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
James T. Meyer et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2019)
CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
Weimin Wang et al.
NATURE (2019)
Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors
Jo Alen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 Pathway
Benjamin J. R. Moore et al.
ACS OMEGA (2019)
T Cells as an Emerging Target for Chronic Pain Therapy
Geoffroy Laumet et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Leaky splicing variant in sepiapterin reductase deficiency Are milder cases escaping diagnosis?
Yu Nakagama et al.
NEUROLOGY-GENETICS (2019)
Combining Human and Rodent Genetics to Identify New Analgesics
Alban Latremoliere et al.
NEUROSCIENCE BULLETIN (2018)
Hyaluronic Acid in the Third Millennium
Arianna Fallacara et al.
POLYMERS (2018)
Evaluation of different classes of histamine H-1 and H-2 receptor antagonist effects on neuropathic nociceptive behavior following tibial nerve transection in rats
Emad Khahlzadeh et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2018)
Current Screening Methodologies in Drug Discovery for Selected Human Diseases
Olga Maria Lage et al.
MARINE DRUGS (2018)
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer
Shane J. F. Cronin et al.
NATURE (2018)
Sepiapterin reductase deficiency: Report of 5 new cases
Sarah AlSubhi et al.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY (2017)
The role of carbonyl reductase 1 in drug discovery and development
Sophia M. Shi et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2017)
Endogenous inspired biomineral-installed hyaluronan nanoparticles as pH-responsive carrier of methotrexate for rheumatoid arthritis
Md. Mahmudul Alam et al.
JOURNAL OF CONTROLLED RELEASE (2017)
Human Tissue Distribution of Carbonyl Reductase 1 Using Proteomic Approach With Liquid Chromatography-Tandem Mass Spectrometry
Wenyi Hua et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death
Saskia Klutzny et al.
CELL DEATH & DISEASE (2017)
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
Nicholas W. Bellono et al.
CELL (2017)
Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia
Chiho Sumi-Ichinose et al.
PHYSIOLOGICAL REPORTS (2017)
Tetrahydrobiopterin Biosynthesis as a Potential Target of the Kynurenine Pathway Metabolite Xanthurenic Acid
Hirohito Haruki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Endogenous analgesia mediated by CD4+ T lymphocytes is dependent on enkephalins in mice
Lilian Basso et al.
JOURNAL OF NEUROINFLAMMATION (2016)
EXTRACELLULAR MATRIX HYALURONAN SIGNALS VIA ITS CD44 RECEPTOR IN THE INCREASED RESPONSIVENESS TO MECHANICAL STIMULATION
L. F. Ferrari et al.
NEUROSCIENCE (2016)
Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations
Robert R. Edwards et al.
PAIN (2016)
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
S. Ma et al.
CELL DEATH & DISEASE (2016)
Novel hyaluronic acid-methotrexate conjugate suppresses joint inflammation in the rat knee: efficacy and safety evaluation in two rat arthritis models
Tatsuya Tamura et al.
ARTHRITIS RESEARCH & THERAPY (2016)
Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target
Lisette P. Yco et al.
BMC CANCER (2015)
Urine sepiapterin excretion as a new diagnostic marker for sepiapterin reductase deficiency
Claudia Carducci et al.
MOLECULAR GENETICS AND METABOLISM (2015)
The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase
Lucas Vicuna et al.
NATURE MEDICINE (2015)
Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway
Alban Latremoliere et al.
NEURON (2015)
CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity
Nader Ghasemlou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
Shaojun Yang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Clinical and genetic studies in a family with a novel mutation in the sepiapterin reductase gene
J. Koht et al.
ACTA NEUROLOGICA SCANDINAVICA (2014)
A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia
Inna Belfer et al.
AMERICAN JOURNAL OF HEMATOLOGY (2014)
Tetrahydrobiopterin in Cardiovascular Health and Disease
Jennifer K. Bendall et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Endogenous Regulation of Visceral Pain via Production of Opioids by Colitogenic CD4+ T Cells in Mice
Jerome Boue et al.
GASTROENTEROLOGY (2014)
Novel Interaction of Ornithine Decarboxylase with Sepiapterin Reductase Regulates Neuroblastoma Cell Proliferation
Ingo Lange et al.
JOURNAL OF MOLECULAR BIOLOGY (2014)
Capsaicinoids in the treatment of neuropathic pain: a review
John F. Peppin et al.
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2014)
Phenotypic vs. Target-Based Drug Discovery for First-in-Class Medicines
D. C. Swinney
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Serotonin signalling in the gut-functions, dysfunctions and therapeutic targets
Gary M. Mawe et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)
VERY EARLY PATTERN OF MOVEMENT DISORDERS IN SEPIAPTERIN REDUCTASE DEFICIENCY
Vincenzo Leuzzi et al.
NEUROLOGY (2013)
Tetrahydrobiopterin Biosynthesis as an Off-Target of Sulfa Drugs
Hirohito Haruki et al.
SCIENCE (2013)
Tissue Distribution, Ontogeny, and Chemical Induction of Aldo-Keto Reductases in Mice
Matthew Pratt-Hyatt et al.
DRUG METABOLISM AND DISPOSITION (2013)
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
Christopher A. Lipinski et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
Sepiapterin reductase deficiency: A Treatable Mimic of Cerebral Palsy
Jennifer Friedman et al.
ANNALS OF NEUROLOGY (2012)
A randomised, double-blind, controlled trial comparing two intra-articular hyaluronic acid preparations differing by their molecular weight in symptomatic knee osteoarthritis
Francis Berenbaum et al.
ANNALS OF THE RHEUMATIC DISEASES (2012)
A Comprehensive Survey of Ras Mutations in Cancer
Ian A. Prior et al.
CANCER RESEARCH (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Analgesia by inhibiting tetrahydrobiopterin synthesis
Michael Costigan et al.
CURRENT OPINION IN PHARMACOLOGY (2012)
Tetrahydrobiopterin: biochemistry and pathophysiology
Ernst R. Werner et al.
BIOCHEMICAL JOURNAL (2011)
Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch
P. Anand et al.
BRITISH JOURNAL OF ANAESTHESIA (2011)
GCH1, BH4 and Pain
Alban Latremoliere et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2011)
Role of Increased Guanosine Triphosphate Cyclohydrolase-1 Expression and Tetrahydrobiopterin Levels upon T Cell Activation
Wei Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis
Christopher Chidley et al.
NATURE CHEMICAL BIOLOGY (2011)
How were new medicines discovered?
David C. Swinney et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression
Young-Rak Cho et al.
ONCOLOGY REPORTS (2011)
Precision Mapping of an In Vivo N-Glycoproteome Reveals Rigid Topological and Sequence Constraints
Dorota F. Zielinska et al.
CELL (2010)
Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer
P. W. Gout et al.
Current Oncology (2010)
Sepiapterin Reductase Deficiency: Two Indian Siblings with Unusual Clinical Features
Gurusidheshwar M. Wali et al.
MOVEMENT DISORDERS (2010)
The necessity of animal models in pain research
Jeffrey S. Mogil et al.
PAIN (2010)
Sleep and Rhythm Consequences of a Genetically Induced Loss of Serotonin
Smaranda Leu-Semenescu et al.
SLEEP (2010)
Immune Modulation with Sulfasalazine Attenuates Immunopathogenesis but Enhances Macrophage-Mediated Fungal Clearance during Pneumocystis Pneumonia
Jing Wang et al.
PLOS PATHOGENS (2010)
Expression Analysis of the Aldo-Keto Reductases Involved in the Novel Biosynthetic Pathway of Tetrahydrobiopterin in Human and Mouse Tissues
Haruka Hirakawa et al.
JOURNAL OF BIOCHEMISTRY (2009)
T-Cell Infiltration and Signaling in the Adult Dorsal Spinal Cord Is a Major Contributor to Neuropathic Pain-Like Hypersensitivity
Michael Costigan et al.
JOURNAL OF NEUROSCIENCE (2009)
Effective relief of neuropathic pain by adeno-associated virus-mediated expression of a small hairpin RNA against GTP cyclohydrolase I
Sung Jin Kim et al.
MOLECULAR PAIN (2009)
Animal models of pain: progress and challenges
Jeffrey S. Mogil
NATURE REVIEWS NEUROSCIENCE (2009)
Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation
Alicia R. Folgueras et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice - as a mouse model for Parkinson's disease
Chisato Takazawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase
Satoshi Endo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Sulfasalazine blocks the development of tactile allodynia in diabetic rats
Liliana N. Berti-Mattera et al.
DIABETES (2008)
CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain
Ling Cao et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Absorption, Uptake and Tissue Affinity of High-Molecular-Weight Hyaluronan after Oral Administration in Rats and Dogs
Lajos Balogh et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
Tissue Distribution of Human AKR1C3 and Rat Homolog in the Adult Genitourinary System
Joseph Azzarello et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2008)
Two Greek siblings with sepiapterin reductase deficiency
Marcel M. Verbeekac et al.
MOLECULAR GENETICS AND METABOLISM (2008)
Immune cell involvement in dorsal root ganglia and spinal cord after chronic constriction or transection of the rat sciatic nerve
Ping Hu et al.
BRAIN BEHAVIOR AND IMMUNITY (2007)
Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinorna cells expressing AXL
Jong-Ding Lay et al.
CANCER RESEARCH (2007)
Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the shortchain dehydrogenase/reductase superfamily
Frank Hoffmann et al.
DRUG METABOLISM REVIEWS (2007)
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence
Irmgard Tegeder et al.
NATURE MEDICINE (2006)
Sepiapterin reductase deficiency an autosomal recessive DOPA-responsive dystonia
Nico G. Abeling et al.
MOLECULAR GENETICS AND METABOLISM (2006)
A murine model for human sepiapterin-reductase deficiency
S Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Synthesis and evaluation of hydrolyzable hyaluronan-tethered bupivacaine delivery systems
DA Gianolio et al.
BIOCONJUGATE CHEMISTRY (2005)
Sepiapterin reductase deficiency: a congenital dopa-responsive motor and cognitive disorder
BGR Neville et al.
BRAIN (2005)
Effects of sulfasalazine on sperm acrosome reaction and gene expression in the male reproductive organs of rats
T Fukushima et al.
TOXICOLOGICAL SCIENCES (2005)
The role of mast cells in the pathogenesis of pain in chronic pancreatitis
WA Hoogerwerf et al.
BMC GASTROENTEROLOGY (2005)
T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats
G Moalem et al.
NEUROSCIENCE (2004)
The metabolic and molecular bases of tetrahydroblopterin-responsive phenylalanine hydroxylase deficiency
N Blau et al.
MOLECULAR GENETICS AND METABOLISM (2004)
Tetrahydrobiopterin is synthesized from 6-pyruvoyl-tetrahydropterin by the human aldo-keto reductase AKR1 family members
T Iino et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Detection of sepiapterin in CSF of patients with sepiapterin reductase deficiency
G Zorzi et al.
MOLECULAR GENETICS AND METABOLISM (2002)
Macrophage and lymphocyte invasion of dorsal root ganglia after peripheral nerve lesions in the rat
P Hu et al.
NEUROSCIENCE (2002)
Reduced nitric oxide metabolites in CSF of patients with tetrahydrobiopterin deficiency
G Zorzi et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc- cystine transporter:: a new action for an old drug
PW Gout et al.
LEUKEMIA (2001)
Mutations in the sepiapterin reductase gene cause a novel tetrahydrobiopterin-dependent monoamine-neurotransmitter deficiency without hyperphenylalaninemia
L Bonafé et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation
KM Sakamoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Possible role of inflammatory mediators in tactile hypersensitivity in rat models of mononeuropathy
JG Cui et al.
PAIN (2000)
Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily:: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
TM Penning et al.
BIOCHEMICAL JOURNAL (2000)
Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury
T Liu et al.
PAIN (2000)
The enzyme that synthesizes tetrahydrobiopterin from 6-pyruvoyl-tetrahydropterin in the lemon mutant silkworm consists of two carbonyl reductases
T Iino et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice
RA Ribeiro et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
分享论文
