相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model
Ilie Cosmin Stancu et al.
GLIA (2022)
Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy
Maiko Ono et al.
AGING CELL (2022)
A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model
Taeko Kimura et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2022)
High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies
Kenji Tagai et al.
NEURON (2021)
Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease
Akira Sobue et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2021)
Structure-based classification of tauopathies
Yang Shi et al.
NATURE (2021)
Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates
Jack H. Brelstaff et al.
SCIENCE ADVANCES (2021)
Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor
Jun Maeda et al.
BRAIN COMMUNICATIONS (2021)
Developmental Pathogenicity of 4-Repeat Human Tau Is Lost with the P301L Mutation in Genetically Matched Tau-Transgenic Mice
Julia E. Gamache et al.
JOURNAL OF NEUROSCIENCE (2020)
A neuroscientist's guide to transgenic mice and other genetic tools
Shaghayegh Navabpour et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2020)
Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation
Takashi Saito et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
Julia Gamache et al.
NATURE COMMUNICATIONS (2019)
Tau binding protein CAPON induces tau aggregation and neurodegeneration
Shoko Hashimoto et al.
NATURE COMMUNICATIONS (2019)
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
Tiffany Wu et al.
CELL REPORTS (2019)
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis
Leslie O. Goodwin et al.
GENOME RESEARCH (2019)
In Vivo Visualization of Tau Accumulation, Microglial Activation, and Brain Atrophy in a Mouse Model of Tauopathy rTg4510
Ai Ishikawa et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Comparative In Vitro and In Vivo Quantifications of Pathologic Tau Deposits and Their Association with Neurodegeneration in Tauopathy Mouse Models
Ruiqing Ni et al.
JOURNAL OF NUCLEAR MEDICINE (2018)
Selective vulnerability in neurodegenerative diseases
Hongjun Fu et al.
NATURE NEUROSCIENCE (2018)
ALZHEIMER DISEASE Rodent models for Alzheimer disease
Juergen Goetz et al.
NATURE REVIEWS NEUROSCIENCE (2018)
Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease
Alexandra Litvinchuk et al.
NEURON (2018)
Glial contributions to neurodegeneration in tauopathies
Cheryl E. G. Leyns et al.
MOLECULAR NEURODEGENERATION (2017)
TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
Cheryl E. G. Leyns et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Intracellular Fibroblast Growth Factor 14: Emerging Risk Factor for Brain Disorders
Jessica Di Re et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
In Vivo Tau imaging for a Diagnostic Platform of Tauopathy Using the rTg4510 Mouse Line
Naruhiko Sahara et al.
FRONTIERS IN NEUROLOGY (2017)
Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study
Naruhiko Sahara et al.
NEUROBIOLOGY OF AGING (2014)
Biochemical distribution of tau protein in synaptosomal fraction of transgenic mice expressing human P301L tau
Naruhiko Sahara et al.
FRONTIERS IN NEUROLOGY (2014)
In vivo functional brain mapping in a conditional mouse model of human tauopathy (taup301l) reveals reduced neural activity in memory formation structures
Pablo D. Perez et al.
MOLECULAR NEURODEGENERATION (2013)
Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls
Masahiro Maruyama et al.
NEURON (2013)
Strain Background Influences Neurotoxicity and Behavioral Abnormalities in Mice Expressing the Tetracycline Transactivator
Harry J. Han et al.
JOURNAL OF NEUROSCIENCE (2012)
Site-specific integration and tailoring of cassette design for sustainable gene transfer
Angelo Lombardo et al.
NATURE METHODS (2011)
Site-specific integrase-mediated transgenesis in mice via pronuclear injection
Bosiljka Tasic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
Brian R. Hoover et al.
NEURON (2010)
Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology
Manuela Polydoro et al.
JOURNAL OF NEUROSCIENCE (2009)
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells
Omar Nyabi et al.
NUCLEIC ACIDS RESEARCH (2009)
Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau
Tetsuya Kimura et al.
EMBO JOURNAL (2007)
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
Yasumasa Yoshiyama et al.
NEURON (2007)
Cortical neuronal and glial pathology in TgTauP301L transgenic mice -: Neuronal degeneration, memory disturbance, and phenotypic variation
Tetsuro Murakami et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
Katharina Schindowski et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice
L. Pennanen et al.
GENES BRAIN AND BEHAVIOR (2006)
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
TL Spires et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)
M Ramsden et al.
JOURNAL OF NEUROSCIENCE (2005)
Tau suppression in a neurodegenerative mouse model improves memory function
K SantaCruz et al.
SCIENCE (2005)
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L Tau transgenic mice
DC David et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
C Andorfer et al.
JOURNAL OF NEUROSCIENCE (2005)
Changed conformation of mutant tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of tau-4R/2N transgenic mice
D Terwel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice
L Pennanen et al.
NEUROBIOLOGY OF DISEASE (2004)
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
C Andorfer et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family
A Lossos et al.
JOURNAL OF NEUROLOGY (2003)
Filamentous tau in oligodendrocytes and astrocytes of transgenic mice expressing the human tau isoform with the P301L mutation
WL Lin et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebral ataxia
JC van Swieten et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
Ultrastructural neuronal pathology in transgenic mice expressing mutant (P301L) human tau
WL Lin et al.
JOURNAL OF NEUROCYTOLOGY (2003)
Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility
N Sahara et al.
JOURNAL OF NEUROCHEMISTRY (2002)
FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and tau filaments in forebrain
F Lim et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2001)
Tau filament formation in transgenic mice expressing P301L tau
J Götz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Neurotrophins are required for nerve growth during development
KL Tucker et al.
NATURE NEUROSCIENCE (2001)
Neurodegenerative tauopathies
VMY Lee et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
J Lewis et al.
NATURE GENETICS (2000)
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
A Probst et al.
ACTA NEUROPATHOLOGICA (2000)
Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes
K Duff et al.
NEUROBIOLOGY OF DISEASE (2000)
分享论文
