期刊
EMERGING MICROBES & INFECTIONS
卷 12, 期 1, 页码 -出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/22221751.2023.2195019
关键词
SARS-CoV-2; COVID-19; dendritic cell; immunopathology; viral infection
COVID-19, caused by SARS-CoV-2, is a major infectious threat to global public health. Dendritic cells play important roles in viral transmission and clinical progression, and understanding their mechanisms and immunological characteristics in SARS-CoV-2 infection is crucial.
The persistent pandemic of coronavirus disease in 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently poses a major infectious threat to public health around the world. COVID-19 is an infectious disease characterized by strong induction of inflammatory cytokines, progressive lung inflammation, and potential multiple organs dysfunction. SARS-CoV-2 infection is closely related to the innate immune system and adaptive immune system. Dendritic cells (DCs), as a bridge connecting innate immunity and adaptive immunity, play many important roles in viral diseases. In this review, we will pay special attention to the possible mechanism of dendritic cells in human viral transmission and clinical progression of diseases, as well as the reduction and dysfunction of DCs in severe SARS-CoV-2 infection, so as to understand the mechanism and immunological characteristics of SARS-CoV-2 infection.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据