期刊
CANCER MEDICINE
卷 12, 期 11, 页码 12874-12880出版社
WILEY
DOI: 10.1002/cam4.6118
关键词
clinical management; clinical trials; community outreach; medical oncology; screening
类别
This pilot study aimed to examine the feasibility of a nurse-led intervention for adults with newly diagnosed cancer and undiagnosed or untreated type 2 diabetes. The study found recruitment inefficiencies but overall acceptance of the intervention among eligible participants.
BackgroundUndiagnosed Type 2 diabetes (T2D) has been associated with advanced stage cancer at diagnosis, higher mortality, and lower long-term all-cause survival. This was a RCT pilot study to examine the feasibility of a nurse-led T2D intervention for adults with newly diagnosed cancer (<= 3 months), and T2D, undiagnosed or untreated with medication, conducted at an outpatient oncology clinic affiliated with a large academic institution. MethodsParticipants needed to meet the eligibility criteria including a HbA1c level between 6.5% and 9.9%. Randomization was 1:1 to a 3-month intervention that consisted of nursing-led diabetes education and immediate initiation of metformin versus referral to primary care for usual care (control). ResultsThree hundred and seventy nine patients were screened using EHR, 55 agreed to participate, and 3 had eligible HbA1c levels and were randomized in the study. Primary reasons for study exclusion included life expectancy <= 2 years (16.9%), current use or inability to tolerate metformin (14.8%), and abnormal labs that contraindicated metformin use (13.9%). ConclusionThis study was not feasible due to recruitment inefficiencies, but acceptable to all who qualified.
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