4.5 Article

Dynamic functional hippocampal markers of residual depressive symptoms in euthymic bipolar disorder

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Clinical Neurology

Structural and functional MRI correlates of inflammation in bipolar disorder: A systematic review

Luigi F. Saccaro et al.

Summary: This systematic review analyzed the presentation of immune-related histological and functional magnetic resonance imaging (MRI) in patients with bipolar disorder (BD). The results showed that BD patients had abnormal MRI findings associated with inflammatory diseases and chronic inflammation. However, the generalizability of the study conclusions is limited due to heterogeneity in methods and results, as well as limitations in sample sizes. The qualitative synthesis revealed that the links between immune traits and functional or structural MRI alterations in BD point towards brain areas involved in affective and somatomotor processing, with a trend towards a negative correlation between peripheral inflammatory markers and brain region volume. Disentangling the complex relationship between the immune system and MRI alterations in BD may uncover mechanisms underlying symptom pathophysiology, potentially leading to quickly translatable diagnostic, prognostic, and therapeutic implications.

JOURNAL OF AFFECTIVE DISORDERS (2023)

Article Neurosciences

In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics throughMeta-AnalysisBipolar Disorder Working Group

Unn K. Haukvik et al.

Summary: By studying the volume of hippocampal subfields in individuals with bipolar disorder, this research found that there are widespread reductions in several subfields in bipolar disorder, compared to healthy controls. The use of medication, particularly lithium, may have a protective effect in bipolar disorder.

HUMAN BRAIN MAPPING (2022)

Article Clinical Neurology

Restoration of default mode network and task positive network anti-correlation associated with mindfulness-based cognitive therapy for bipolar disorder

Tina Chou et al.

Summary: Individuals with bipolar disorder show abnormalities in the default mode network and task positive network connectivity, which can be restored by mindfulness-based cognitive therapy.

PSYCHIATRY RESEARCH-NEUROIMAGING (2022)

Article Psychology, Clinical

Inflammation is correlated with abnormal functional connectivity in unmedicated bipolar depression: an independent component analysis study of resting-state fMRI

Guixian Tang et al.

Summary: The study found that serum IL-8 levels are associated with impaired FC in the right precentral gyrus in BD II patients, suggesting that inflammation might play a crucial role in brain functional abnormalities in BD.

PSYCHOLOGICAL MEDICINE (2022)

Article Neurosciences

Aberrant Functional Connectivity of Sensorimotor Network and Its Relationship With Executive Dysfunction in Bipolar Disorder Type I

Wenjing Zhu et al.

Summary: This study investigated the aberrant functional connectivity (FC) of the sensory motor network (SMN) in bipolar disorder type I (BD-I) patients and its potential associations with executive dysfunction. The results showed that BD-I patients had abnormal FC within and between networks, and this abnormal FC was correlated with clinical symptoms and executive function performance.

FRONTIERS IN NEUROSCIENCE (2022)

Article Behavioral Sciences

Alterations in resting-state whole-brain functional connectivity pattern similarity in bipolar disorder patients

Liangliang Ping et al.

Summary: This study investigated the voxel-wise changes of functional connectivity patterns in bipolar disorder (BD) patients using publicly available data. The results showed lower functional connectivity homogeneity values in the left middle temporal gyrus (MTG) in BD patients compared to healthy controls, and decreased functional connectivities between left MTG and other brain regions. The findings also suggested correlations between the functional connectivities of left MTG and symptoms such as insomnia and grandiose delusions in BD patients.

BRAIN AND BEHAVIOR (2022)

Article Neurosciences

Altered dynamic functional connectivity across mood states in bipolar disorder

Min Liu et al.

Summary: This study examined the differences in large-scale brain dynamic functional connectivity between depressive and euthymic states in patients with bipolar disorder using rsfMRI data. The findings suggest that differences in connectivity within and between DMN and SMN networks can help distinguish between mood states in bipolar patients. Abnormal connectivity in the FST circuit may be a distinguishing feature of euthymic BD patients compared to healthy controls.

BRAIN RESEARCH (2021)

Review Clinical Neurology

Portable technologies for digital phenotyping of bipolar disorder: A systematic review

Luigi F. Saccaro et al.

Summary: New technologies present significant opportunities for digital phenotyping of bipolar disorder, with AI-based models likely to provide important support in clinical decision-making. However, the included studies had limitations such as small sample sizes, heterogeneity, and evidence of overfitting, highlighting the need for further research and collaboration among different stakeholders.

JOURNAL OF AFFECTIVE DISORDERS (2021)

Review Neurosciences

Review The many dimensions of human hippocampal organization and (dys)function

Sarah Genon et al.

Summary: The internal organization of the hippocampal formation has been studied for over a century, with recent research highlighting the importance of the anterior-to-posterior axis in addition to the medial-lateral axis. Advances in in vivo parcellation and gradient mapping techniques have provided new insights into hippocampal function and its impact on behavior in healthy and clinical populations.

TRENDS IN NEUROSCIENCES (2021)

Article Neurosciences

Functional connectivity of the hippocampus and its subfields in resting-state networks

Laura Ezama et al.

Summary: Our study investigated how the hippocampus connects to the default mode network and how different hippocampal subfields participate in resting-state networks using a high spatial-resolution 7T resting-state fMRI dataset. The results revealed two main activity hotspots inside the hippocampus, one correlated with the somatomotor network and the other with the default mode network.

EUROPEAN JOURNAL OF NEUROSCIENCE (2021)

Review Behavioral Sciences

Inflammation, anxiety, and stress in bipolar disorder and borderline personality disorder: A narrative review

L. F. Saccaro et al.

Summary: Bipolar disorder (BD) and borderline personality disorder (BPD) share common characteristics such as symptoms, risk factors, and comorbidities. While some studies have focused on the link between stress and peripheral inflammation in other affective disorders, fewer have explored this relationship in BD and BPD.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2021)

Article Neuroimaging

Mood disorders disrupt the functional dynamics, not spatial organization of brain resting state networks

Camille Piguet et al.

Summary: Spontaneous fluctuations in the blood oxygenation level dependent signal have been found to aggregate into multiple functional networks in mood disorder patients. Alterations in resting brain activity appear to correlate with specific clinical symptoms, such as increased self-processing and decreased attention to the external world.

NEUROIMAGE-CLINICAL (2021)

Article Clinical Neurology

Bipolar disorder with and without a history of psychotic features: fMRI correlates of sustained attention

Gianna Sepede et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2020)

Article Neurosciences

TbCAPs: A toolbox for co-activation pattern analysis

Thomas A. W. Bolton et al.

NEUROIMAGE (2020)

Review Biochemistry & Molecular Biology

Rich-club in the brain's macrostructure: Insights from graph theoretical analysis

Dae-Jin Kim et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2020)

Review Clinical Neurology

Cognitive emotional processing across mood disorders

Priyanka Panchal et al.

CNS SPECTRUMS (2019)

Article Clinical Neurology

Hippocampal functional connectivity-based discrimination between bipolar and major depressive disorders

Ahmed Ameen Fateh et al.

PSYCHIATRY RESEARCH-NEUROIMAGING (2019)

Review Neurosciences

Co-activation patterns in resting-state fMRI signals

Xiao Liu et al.

NEUROIMAGE (2018)

Article Multidisciplinary Sciences

Contrasting variability patterns in the default mode and sensorimotor networks balance in bipolar depression and mania

Matteo Martino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Neurosciences

Neurofunctional Topography of the Human Hippocampus

Jennifer L. Robinson et al.

HUMAN BRAIN MAPPING (2015)

Review Clinical Neurology

Hippocampal structure and function in individuals with bipolar disorder: A systematic review

Mara Otten et al.

JOURNAL OF AFFECTIVE DISORDERS (2015)

Article Clinical Neurology

Neural correlates of negative emotion processing in bipolar disorder

Gianna Sepede et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2015)