☆ 4.5 Article

Circ-Bnc2 alleviates neuroinflammation in LPS-stimulated microglial cells to inhibit neuron cell apoptosis through regulating miR-497a-5p/HECTD1 axis

BRAIN AND BEHAVIOR (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Neurosciences

Gut microbiota-brain axis in depression: The role of neuroinflammation

Anelise S. Carlessi et al.

Summary: Major depressive disorder (MDD) is a prevalent psychiatric condition, with studies indicating that inflammation plays a crucial role in its pathogenesis, closely linked to gut microbiota and brain axis. This connection may influence treatment responses and the onset of symptoms.

EUROPEAN JOURNAL OF NEUROSCIENCE (2021)

添加到收藏夹

Review Neurosciences

Neuroinflammation and depression: A review

Romain Troubat et al.

Summary: Neuroinflammation interacts with key neurobiological factors of depression, potentially presenting a crucial therapeutic target for future treatments. This interaction may impact serotonin levels, HPA axis regulation, and hippocampal neurogenesis, leading to the pathophysiological cascade of increased glutamate levels and altered neurotransmission. It can be triggered by chronic inflammatory conditions or primary brain neuroinflammation, highlighting the importance of addressing neuroinflammation in the treatment of major depressive disorder.

EUROPEAN JOURNAL OF NEUROSCIENCE (2021)

添加到收藏夹

Article Integrative & Complementary Medicine

Acupuncture reduces peripheral and brainstem cytokines in rats subjected to lipopolysaccharide-induced inflammation

Caroline C. Ramires et al.

Summary: The study confirmed the anti-inflammatory effect of manual acupuncture at SP6 on LPS-induced peritonitis in rats, reducing inflammatory cell infiltration, vascular permeability, and MPO activity. Pre-treatment with indomethacin and SP6 MA also decreased cytokine levels, showing the potential of acupuncture as an alternative treatment for inflammation.

ACUPUNCTURE IN MEDICINE (2021)

添加到收藏夹

Review Medicine, Research & Experimental

Circular RNAs in depression: Biogenesis, function, expression, and therapeutic potential

Hua Gan et al.

Summary: circRNAs play a crucial role in the development of depression by regulating the expression of target genes and impacting behavioral symptoms. Current research is exploring the potential therapeutic role of circRNAs in depression, which may offer insight into the development of new treatment options.

BIOMEDICINE & PHARMACOTHERAPY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice

Oriana Maria Maurel et al.

Summary: Our study found that the expression of miRNAs in different brain areas is associated with susceptibility/resilience to PTSD. Changes in specific miRNAs may influence the transcription levels of FKBP5 and BDNF, and show a linear correlation with stress-induced behavioral phenotypes.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Cell Biology

Diagnostic Biomarker Hsa_circ_0126218 and Functioning Prediction in Peripheral Blood Monocular Cells of Female Patients With Major Depressive Disorder

Tianyi Bu et al.

Summary: The study identified a large number of dysregulated circRNAs in PBMCs between female MDD patients and healthy controls. Among them, hsa_circ_0126218 was identified as a potential diagnostic biomarker with upregulated expression in MDD patients. Further bioinformatics analysis revealed a network involving hsa_circ_0126218, miRNA, and hub genes related to the pathogenesis of female MDD.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

EPA is More Effective than DHA to Improve Depression-Like Behavior, Glia Cell Dysfunction and Hippcampal Apoptosis Signaling in a Chronic Stress-Induced Rat Model of Depression

Zhilan Peng et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Psychiatry

Circular RNA in Schizophrenia and Depression

Zexuan Li et al.

FRONTIERS IN PSYCHIATRY (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF-κB and TNF-α/TNFR1/NF-κB pathways

Xiang Xu et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

MiR-497 promotes microglia activation and proinflammatory cytokines production in chronic unpredictable stress-induced depression via targeting FGF2

Xiaoyan Zhai et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2020)

添加到收藏夹

Review Cell Biology

Perspectives on Circular RNAs as Prostate Cancer Biomarkers

Jiajie Fang et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

添加到收藏夹

Review Genetics & Heredity

Integration of Bioinformatic Predictions and Experimental Data to Identify circRNA-miRNA Associations

Martina Dori et al.

GENES (2019)

添加到收藏夹

Article Behavioral Sciences

Total saponins from the leaves of Panax notoginseng inhibit depression on mouse chronic unpredictable mild stress model by regulating circRNA expression

Hualin Zhang et al.

BRAIN AND BEHAVIOR (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Cellular and molecular basis for stress-induced depression

J-S Seo et al.

MOLECULAR PSYCHIATRY (2017)

添加到收藏夹

Article Primary Health Care

Depression in Older Adults A Treatable Medical Condition

David A. Casey

PRIMARY CARE (2017)

添加到收藏夹

Review Neurosciences

Microglia: An Interface between the Loss of Neuroplasticity and Depression

Gaurav Singhal et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2017)

添加到收藏夹

Review Neurosciences

Brain-derived Neurotrophic Factor (BDNF)-TrkB Signaling in Inflammation-related Depression and Potential Therapeutic Targets

Ji-chun Zhang et al.

CURRENT NEUROPHARMACOLOGY (2016)

添加到收藏夹

Review Neurosciences

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

Dora Brites et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Mental health: A world of depression

Kerri Smith

NATURE (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

Jason S. Snyder et al.

NATURE (2011)

添加到收藏夹

Article Developmental Biology

The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure

Irene E. Zohn et al.

DEVELOPMENTAL BIOLOGY (2007)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.