Molecular Dynamics Simulation from Symmetry Breaking Changing to Asymmetrical Phospholipid Membranes Due to Variable Capacitors during Resonance with Helical Proteins

Biological symmetry breaking is a mechanism in biosystems that is necessary for human survival, and depends on chemical physics concepts at both microscopic and macroscopic scales. In this work, we present a few mechanisms of the signaling phenomenon that have been studied in various tissues of human origin. We exhibit that anatomical asymmetry in the structure of a membrane can produce a flow of extracellular fluid. Furthermore, we exhibit that membrane asymmetry is a misbalance in the composition of the aqueous phases and interaction forces with the protein trans-membrane. Various biological membranes such as DPPC, DMPC, DLPC, and so on, have considerable electrostatic voltages that extend across the phosphor lipids bilayer. For studying these phenomena, we modeled DPPC, DMPC, and DLPC lipid bilayers with a net charge misbalance across the phospholipids. Because asymmetric membranes create the shifted voltages among the various aqueous tissues, this effect makes the charge misbalances cause a voltage of 1.3 V across the DPPC bilayer and 0.8 V across the DMPC bilayer. This subject exhibits the importance of membrane structures on electrostatic potential gradients. Finally, we exhibited that a quantum effect was created in small parts of the cell's thickness due to the symmetry breaking of asymmetrical phospholipid bilayers.

Automated summary

Biological symmetry breaking is crucial for human survival and relies on chemical physics concepts at both microscopic and macroscopic scales. This study presents various mechanisms of signaling phenomena in human tissues and demonstrates how anatomical asymmetry in membrane structure generates extracellular fluid flow. Membrane asymmetry, resulting from imbalances in aqueous composition and protein trans-membrane interactions, leads to considerable electrostatic voltages in biological membranes. Modelling DPPC, DMPC, and DLPC lipid bilayers with charge misbalances, the study shows that asymmetric membranes create voltage differences across different aqueous tissues. Furthermore, asymmetrical phospholipid bilayers result in quantum effects in small parts of the cell's thickness.