Circulating Biomarkers in Coronary Microvascular Dysfunction

Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in the diagnosis and management of coronary microvascular dysfunction. We present an updated review of circulating biomarkers in coronary microvascular dysfunction representing key pathologic processes, including inflammation, endothelial dysfunction, oxidative stress, coagulation, and other mechanisms.

Automated summary

Coronary microvascular dysfunction is often unrecognized but has significant clinical implications. Circulating biomarkers can provide valuable information for the diagnosis and management of this condition, reflecting key pathological processes like inflammation, endothelial dysfunction, oxidative stress, coagulation, and others.