4.6 Article

Genome dynamics of high-risk resistant and hypervirulent Klebsiella pneumoniae clones in Dhaka, Bangladesh

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Infectious Diseases

A nationwide genomic study of clinical Klebsiella pneumoniae in Norway 2001-15: introduction and spread of ESBLs facilitated by clonal groups CG15 and CG307

Aasmund Fostervold et al.

Summary: The study used nationwide surveillance data to examine longitudinal changes in Klebsiella pneumoniae isolates in Norway, focusing on ESBL-producing strains. The results revealed a diverse ESBL population dominated by specific clonal groups carrying bla(CTX-M-15), indicating convergence of virulence and resistance determinants. Klebsiella variicola was found to be a frequent cause of infection but rarely carried ESBLs.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2022)

Article Infectious Diseases

Association of sequence types, antimicrobial resistance and virulence genes in Indian isolates of Klebsiella pneumoniae: A comparative genomics study

Abhirami Krishnamoorthy Sundaresan et al.

Summary: The study conducted genomic surveillance of Klebsiella pneumoniae in India to understand the spread of antimicrobial resistant genes over a 10-year period and to differentiate between environmental and clinical strains. The results showed the presence of diverse serotypes and sequence types among Klebsiella pneumoniae isolates in India, with a high proportion carrying antimicrobial resistant and virulence genes. These findings are important for the prompt treatment and prevention of Klebsiella pneumoniae dissemination.

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE (2022)

Article Microbiology

Characteristics of Carbapenemase-Producing Klebsiella pneumoniae Isolated in the Intensive Care Unit of the Largest Tertiary Hospital in Bangladesh

Takashi Okanda et al.

Summary: This study genetically characterized carbapenemase-producing Klebsiella pneumoniae isolates in a tertiary hospital in Bangladesh, revealing a variety of resistance genes and high prevalence of 16S rRNA methyltransferase. The isolates were classified into 14 different sequence types, with dominant STs including ST34 and ST147. The emergence of pandrug-resistant strains, particularly ST147, ST231, and ST14, poses a significant challenge in the spread of antimicrobial drug resistance.

FRONTIERS IN MICROBIOLOGY (2021)

Article Microbiology

International High-Risk Clones Among Extended-Spectrum β-Lactamase-Producing Escherichia coli in Dhaka, Bangladesh

Razib Mazumder et al.

Summary: This study reveals a high diversity of E. coli lineages among ESBL-producing E. coli from Dhaka, with ongoing circulation of ST131 and other major non-ST131 high-risk clones that are strongly associated with cephalosporin resistance and virulence genes, highlighting the need for prospective monitoring of high-risk clones to prevent worsening of the AMR crises.

FRONTIERS IN MICROBIOLOGY (2021)

Article Microbiology

Genotypic Characterization of Clinical Klebsiella spp. Isolates Collected From Patients With Suspected Community-Onset Sepsis, Sweden

Patricia Saxenborn et al.

Summary: Characterization of Klebsiella spp. in community-onset infections revealed high diversity and traits through whole-genome sequencing. Misidentifications of other species than K. pneumoniae are more common than previously described due to conventional microbiological methods. High rates of genotypic multidrug resistance were observed within the K. pneumoniae complex, highlighting the importance of using high-resolution genotypic methods for clinical isolates identification.

FRONTIERS IN MICROBIOLOGY (2021)

Article Biochemistry & Molecular Biology

Hypervirulent Klebsiella pneumoniae Sequence Type 420 with a Chromosomally Inserted Virulence Plasmid

Elias Eger et al.

Summary: This study conducted both genomic and phenotypic experiments to analyze two K. pneumoniae isolates causing severe multiple site infection in a human patient. It revealed that the isolates belong to sequence type 420, suggesting they are of the hypervirulent pathotype, and identified the insertion of a hypervirulence plasmid in the bacterial chromosome mediated by a new IS5 family sub-group IS903 insertion sequence.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Immunology

Antibiotic-Resistant Bacteremia in Young Children Hospitalized With Pneumonia in Bangladesh Is Associated With a High Mortality Rate

Mohammod Jobayer Chisti et al.

Summary: This study investigated the causes of bacteremia and death among children with pneumonia in Dhaka, Bangladesh, finding that antibiotic-resistant Gram-negative bacteremia was associated with high mortality rates. The research highlights the urgent need for new approaches to prevent and treat these infections in order to save young children's lives in the region.

OPEN FORUM INFECTIOUS DISEASES (2021)

Article Infectious Diseases

Emergence of clinical isolates of highly carbapenem-resistant Klebsiella pneumoniae co-harboring blaNDM-5 and blaOXA-181 or-232 in Nepal

Jatan B. Sherchan et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

Review Infectious Diseases

Antibiotic resistance in Bangladesh: A systematic review

Iftekhar Ahmed et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2019)

Article Infectious Diseases

Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307

Kelly L. Wyres et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2019)

Letter Infectious Diseases

Emergence of an MDR Klebsiella pneumoniae ST231 producing OXA-232 and RmtF in Switzerland

Stefano Mancini et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018)

Article Microbiology

Kaptive Web: User-Friendly Capsule and Lipopolysaccharide Serotype Prediction for Klebsiella Genomes

Ryan R. Wick et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2018)

Article Biochemical Research Methods

Phandango: an interactive viewer for bacterial population genomics

James Hadfield et al.

BIOINFORMATICS (2018)

Review Microbiology

Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance

Shiri Navon-Venezia et al.

FEMS MICROBIOLOGY REVIEWS (2017)

Review Microbiology

Klebsiella pneumoniae: Going on the Offense with a Strong Defense

Michelle K. Paczosa et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2016)

Review Biochemistry & Molecular Biology

Klebsiella pneumoniae Population Genomics and Antimicrobial-Resistant Clones

Kelly L. Wyres et al.

TRENDS IN MICROBIOLOGY (2016)

Article Biochemical Research Methods

Roary: rapid large-scale prokaryote pan genome analysis

Andrew J. Page et al.

BIOINFORMATICS (2015)

Article Medicine, Research & Experimental

A high-resolution genomic analysis of multidrug-resistant hospital outbreaks of Klebsiella pneumoniae

Hao Chung The et al.

EMBO MOLECULAR MEDICINE (2015)

Article Multidisciplinary Sciences

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

Kathryn E. Holt et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins

Nicholas J. Croucher et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Microbiology

In Silico Detection and Typing of Plasmids using PlasmidFinder and Plasmid Multilocus Sequence Typing

Alessandra Carattoli et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)

Article Biochemical Research Methods

Prokka: rapid prokaryotic genome annotation

Torsten Seemann

BIOINFORMATICS (2014)

Article Biochemical Research Methods

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

Alexandros Stamatakis

BIOINFORMATICS (2014)

Article Biochemical Research Methods

QUAST: quality assessment tool for genome assemblies

Alexey Gurevich et al.

BIOINFORMATICS (2013)

Article Biochemical Research Methods

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

Anton Bankevich et al.

JOURNAL OF COMPUTATIONAL BIOLOGY (2012)

Article Microbiology

Emerging Severe and Fatal Infections Due to Klebsiella pneumoniae in Two University Hospitals in France

Dominique Decre et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2011)

Article Biochemistry & Molecular Biology

VFDB: a reference database for bacterial virulence factors

LH Chen et al.

NUCLEIC ACIDS RESEARCH (2005)