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Letter
Infectious Diseases
Ryuta Uraki et al.
LANCET INFECTIOUS DISEASES
(2023)
Article
Multidisciplinary Sciences
Yunlong Cao et al.
Summary: Continuous evolution of Omicron has led to the emergence of multiple variants with growth advantages, and mutations in their receptor-binding domain have converged on several hotspots, allowing them to evade neutralizing antibody drugs and convalescent plasma. Breakthrough infections of BA.2 and BA.5 have reduced the diversity of neutralizing antibody binding sites and promoted convergent evolution in the RBD.
Review
Public, Environmental & Occupational Health
Kuldeep Dhama et al.
Summary: Newly emerging variants of SARS-CoV-2 continuously pose global public health concerns and can lead to waves of COVID-19 pandemic. These variants can spread quickly across countries, cause severe disease and reduce the efficacy of current vaccines and immunotherapies. The Omicron variant, first identified in South Africa, is currently the only variant of interest. This review provides an overview of SARS-CoV-2 variants, with a focus on the Omicron variant, its lineages, and hybrid variants. The challenges and strategies to counter the Omicron variant amid the ongoing COVID-19 pandemic are also discussed.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2023)
Article
Environmental Sciences
Md. Aminul Islam et al.
Summary: Wastewater based epidemiology (WBE) is an important tool in fighting COVID-19, providing cost-effective, rapid, and non-invasive insights into the health status of populations. Wastewater monitoring can reduce the burden on public health systems, aid in pandemic management, and guide informed decision-making to protect public health.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Medicine, General & Internal
Queenie Fernandes et al.
Summary: The emergence of novel and evolving variants of SARS-CoV-2 has created the need for newer and more adaptive diagnostic methods. However, developing rapid and sensitive diagnostic technologies has become more challenging due to emerging variants and varying symptoms. Vaccines and drugs are essential for prevention and protection, and constant development is underway. This review discusses the challenges posed by novel variants and the evolution of diagnostic techniques, as well as the development, mechanisms, advantages, and drawbacks of vaccines and drugs and their immunological impact.
ANNALS OF MEDICINE
(2022)
Review
Immunology
Md. Aminul Islam et al.
Summary: SARS-CoV-2, a novel coronavirus strain, has caused a devastating global outbreak with millions of deaths and infections. The human immune system plays a critical role in fighting against the virus, and measures such as dietary supplements, medicinal plants, and personal habits can help strengthen the immune system and prevent viral infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Medicine, General & Internal
Hikmet Akkiz
Summary: SARS-CoV-2 continues to evolve with novel variants that have spike protein mutations, some of which can increase viral replication, raise the risk of reinfection, and weaken the potency of neutralizing antibodies. The Alpha, Beta, Gamma, Delta, and Omicron variants are of particular concern due to their spike protein mutations that may evade neutralizing antibodies.
FRONTIERS IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Carissa Wong
Review
Microbiology
Hao Zhou et al.
Summary: The SARS-CoV-2 virus is continuously evolving and mutating, with the emergence of the highly mutated and transmissible Omicron variant. This variant evades protection from vaccines and antibody-based therapies, but is sensitive to certain antiviral drugs. Understanding the virology and immune mechanisms of the Omicron variant is crucial for developing effective vaccines and treatments.
CLINICAL MICROBIOLOGY REVIEWS
(2022)
Article
Immunology
Hanzhong Ke et al.
Summary: Since being declared a variant of concern by the WHO, the Omicron variant has caused a surge of cases worldwide. It has extensive mutations in its spike glycoprotein, allowing it to evade antiviral immunity provided by vaccination and other means. The Omicron subvariants BA.1, BA.2, BA.2.12.1, BA.4, and BA.5 have additional unique mutations in their spike proteins, further enhancing their immune evasion capabilities.
Article
Biology
Md Minhas Hossain Sakib et al.
Summary: The study found that peptides may be effective drugs against SARS-CoV-2, with AVP1795 identified as the most promising candidate that could inhibit the recognition of SARS-CoV-2 by hACE2 as predicted by molecular dynamics simulation. Peptide-protein interactions were substantially influenced by hydrogen bonding and hydrophobic interactions.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Environmental Sciences
Firoz Ahmed et al.
Summary: The study successfully detected SARS-CoV-2 genetic material in the vicinity wastewaters of an isolation centre in Southeastern Bangladesh, with accumulation of SARS-CoV-2 RNA in the main sewer observed. The findings suggest that monitoring major drains may illustrate the health status of the city, eliminating the need to monitor every wastewater system.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Proceedings Paper
Computer Science, Information Systems
Sakhawat Hossen et al.
Summary: This study introduces a low-cost Ultraviolet disinfection system for ambulances to reduce the spread of SARS-CoV-2. The system, featuring portability and lightweight design, can provide the necessary disinfection dose in a short period of time.
PROCEEDINGS OF INTERNATIONAL CONFERENCE ON ELECTRONICS, COMMUNICATIONS AND INFORMATION TECHNOLOGY 2021 (ICECIT 2021)
(2021)
