4.7 Article

Gut microbiota in patients with COVID-19 and type 2 diabetes: A culture-based method

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Nutrition & Dietetics

Gut Microbiota and Complications of Type-2 Diabetes

Camelia Oana Iatcu et al.

Summary: The gut microbiota plays a crucial role in the development of obesity, metabolic syndrome, and type 2 diabetes. Modulating the gut microbiota through probiotics, prebiotics, synbiotics, and fecal microbial transplantation shows potential in treating diabetes and its complications. The severity of gut microbiota dysbiosis is associated with disease severity, and restoration of the gut microbiota through probiotic administration can improve symptoms and disease progression.

NUTRIENTS (2022)

Review Virology

Immunoregulatory Intestinal Microbiota and COVID-19 in Patients with Type Two Diabetes: A Double-Edged Sword

Pavlo Petakh et al.

Summary: COVID-19 not only affects the lungs but also the gastrointestinal (GI) tract, and the dysbiotic modulations in the intestine can influence the severity of the disease. Type 2 diabetes is one of the most common comorbidities in COVID-19 patients, and metformin, a medication used to treat this condition, shows promise in improving the disease course.

VIRUSES-BASEL (2022)

Article Immunology

Pathogen Species Is Associated With Mortality in Nosocomial Bloodstream Infection in Patients With COVID-19

Juan Gago et al.

Summary: The study found that NBSIs primarily occurred in severely ill COVID-19 patients and were associated with higher mortality. Early recognition of risk factors among COVID-19 patients could potentially decrease NBSI-associated mortality through early treatment.

OPEN FORUM INFECTIOUS DISEASES (2022)

Review Virology

Evolution of the SARS-CoV-2 omicron variants BA.1 to BA.5: Implications for immune escape and transmission

Lok Bahadur Shrestha et al.

Summary: The Omicron variant of SARS-CoV-2 is a major public health concern due to its high infectivity and antibody evasion. It has rapidly become the dominant variant worldwide and has evolved through several variants. The evolution of Omicron is thought to be influenced by zoonotic spillage, infection in immunocompromised individuals, and undiagnosed spread in the community. Current research suggests that Omicron is more infectious than the original Wuhan-Hu-1 and Delta variants, but less severe in terms of its impact on lung tissue. Vaccines have shown reduced effectiveness against Omicron, but booster shots can improve efficacy. Broadly neutralizing monoclonal antibodies have limited effectiveness against Omicron, with some exceptions. New variants, such as BA.4 and BA.5, are emerging and are reported to be more transmissible and resistant to immunity generated by previous variants and monoclonal antibodies.

REVIEWS IN MEDICAL VIROLOGY (2022)

Review Immunology

Microbial dysbiosis in the gut drives systemic autoimmune diseases

Walaa K. Mousa et al.

Summary: The interaction between gut microbes and the immune system plays a crucial role in the development and treatment of systemic autoimmune diseases. Understanding how gut microbes can trigger or protect from these diseases can help us tackle them through dietary and lifestyle changes, microbiome-based therapies, identification of diagnostic biomarkers, and intervention with microbial population changes. Considering the microbiome signature as a key player in systemic autoimmune diseases holds promise in transforming these untreatable diseases into manageable or preventable ones.

FRONTIERS IN IMMUNOLOGY (2022)

Article Biochemistry & Molecular Biology

Impact of COVID-19 and Antibiotic Treatments on Gut Microbiome: A Role for Enterococcus spp.

Elda Righi et al.

Summary: This study found that COVID-19 patients receiving antibiotic treatment may shift the gut microbiome composition towards opportunistic bacteria (OBs), particularly Enterococcus. The treatment-induced dysbiosis may impact infections and long-term consequences, providing important clues to the role of gut homeostasis in COVID-19 recovery.

BIOMEDICINES (2022)

Review Microbiology

Characteristics of SARS-CoV-2 and COVID-19

Ben Hu et al.

Summary: This review summarizes the research progress on SARS-CoV-2 and COVID-19, including virology characteristics, pathogenesis, and recent advances in treatment methods. Furthermore, it discusses in detail the potential wildlife hosts and zoonotic origin of this emerging virus.

NATURE REVIEWS MICROBIOLOGY (2021)

Article Medicine, Research & Experimental

Metformin to decrease COVID-19 severity and mortality: Molecular mechanisms and therapeutic potential

Olexandr Kamyshnyi et al.

Summary: The COVID-19 pandemic poses a serious challenge to medicine and science, with analysis indicating that diabetic patients are more prone to severe COVID-19 due to immune dysregulation. Metabolic changes induced by diabetes affect the immunometabolism of lymphocytes, and the use of metformin may be a new approach to reducing disease severity.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Microbiology

Recent advances in culture-based gut microbiome research

Thomas C. A. Hitch et al.

Summary: Gut microbes have a significant impact on the physiology of their hosts, making it crucial to study their diversity and functions for the discovery of new biomolecules and disease treatment. Gut microbiome research is currently advancing through the integration of metagenomics and cultivation, with potential to overcome the advantages and drawbacks of each approach through synergistic usage.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2021)

Review Medicine, General & Internal

How Does COVID-19 Pandemic Impact on Incidence of Clostridioides difficile Infection and Exacerbation of Its Gastrointestinal Symptoms?

Masoumeh Azimirad et al.

Summary: COVID-19 infection often involves gastrointestinal symptoms, and antibiotic treatment may contribute to the occurrence of Clostridioides difficile infection, especially in elderly patients.

FRONTIERS IN MEDICINE (2021)

Review Endocrinology & Metabolism

Type 2 Diabetes Mellitus and COVID-19: A Narrative Review

Salvatore Corrao et al.

Summary: This review discusses the prevalence, pathophysiological mechanisms, and outcomes of COVID-19 infection in people with diabetes, proposing a rationale for using drugs prescribed in patients with diabetes and providing pragmatic clinical recommendations for dealing with COVID-19 in this patient population.

FRONTIERS IN ENDOCRINOLOGY (2021)

Review Cardiac & Cardiovascular Systems

COVID-19 in Relation to Hyperglycemia and Diabetes Mellitus

Hayder M. Al-kuraishy et al.

Summary: COVID-19 caused by SARS-CoV-2 may lead to extrapulmonary manifestations like diabetes mellitus and hyperglycemia, with SARS-CoV-2 infecting the pancreas through ACE2. The severity of SARS-CoV-2 infection in DM patients is associated with preexisting comorbidities and inflammation disorders. Some antidiabetic agents may reduce SARS-CoV-2 severity through modulation of the ACE2 receptor expression.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

Review Pharmacology & Pharmacy

Gut Microbiota Modulation as a Potential Target for the Treatment of Lung Infections

Clenio Silva Cruz et al.

Summary: The interaction between the gut and lung microbiota has a significant impact on host immune system and respiratory infections. Studies have shown that modulation of gut microbiota by probiotics, prebiotics, and synbiotics can reduce the severity and duration of respiratory tract infections.

FRONTIERS IN PHARMACOLOGY (2021)

Article Medicine, General & Internal

Enterococcal bloodstream infections in critically ill patients with COVID-19: a case series

Daniele Roberto Giacobbe et al.

Summary: The cumulative incidence of enterococcal bloodstream infection is high in critically ill patients with COVID-19, with a potential 30-day mortality rate exceeding 40%. The severity of acute clinical conditions, influenced by both viral pneumonia and enterococcal bloodstream infection, may play a crucial role in determining patient outcomes.

ANNALS OF MEDICINE (2021)

Review Peripheral Vascular Disease

COVID-19 and diabetes: A bidirectional relationship

Marcos M. Lima-Martinez et al.

Summary: There is a bidirectional relationship between COVID-19 and diabetes mellitus, with diabetic individuals infected with SARS-CoV-2 having higher rates of hospital admission, severe pneumonia, and mortality compared to non-diabetic individuals. Chronic hyperglycemia and inflammatory state may lead to an exaggerated inflammatory response and increase the risk of acute respiratory distress syndrome.

CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS (2021)

Article Gastroenterology & Hepatology

Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization

Tao Zuo et al.

GASTROENTEROLOGY (2020)

Article Multidisciplinary Sciences

SARS-CoV-2 productively infects human gut enterocytes

Mart M. Lamers et al.

SCIENCE (2020)

Review Infectious Diseases

Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis

Bradley J. Langford et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

Article Endocrinology & Metabolism

Aberrant intestinal microbiota in individuals with prediabetes

Kristine H. Allin et al.

DIABETOLOGIA (2018)

Review Microbiology

Emerging pathogenic links between microbiota and the gut-lung axis

Kurtis F. Budden et al.

NATURE REVIEWS MICROBIOLOGY (2017)

Article Multidisciplinary Sciences

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

Kristoffer Forslund et al.

NATURE (2015)

Article Multidisciplinary Sciences

The microbiota regulates type 2 immunity through RORγt+ T cells

Caspar Ohnmacht et al.

SCIENCE (2015)

Article Infectious Diseases

Immunomodulatory properties of cell wall extract from Enterococcus faecalis CECT7121

Monica Sparo et al.

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES (2014)

Review Biochemistry & Molecular Biology

Role of the Microbiota in Immunity and Inflammation

Yasmine Belkaid et al.

Article Multidisciplinary Sciences

A metagenome-wide association study of gut microbiota in type 2 diabetes

Junjie Qin et al.

NATURE (2012)

Article Multidisciplinary Sciences

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

June L. Round et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)