相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Neuronal identity defines a-synuclein and tau toxicity
Roman Praschberger et al.
NEURON (2023)
New insights into the genetic etiology of Alzheimer's disease and related dementias
Celine Bellenguez et al.
NATURE GENETICS (2022)
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
Chao Wang et al.
NATURE COMMUNICATIONS (2022)
Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration
Gwyneth M. Welch et al.
SCIENCE ADVANCES (2022)
Molecular characterization of selectively vulnerable neurons in Alzheimer's disease
Kun Leng et al.
NATURE NEUROSCIENCE (2021)
Alzheimer's disease
Philip Scheltens et al.
LANCET (2021)
TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease
Seung-Hye Lee et al.
CELL REPORTS (2021)
Neuronal diversity and convergence in a visual system developmental atlas
Mehmet Neset ozel et al.
NATURE (2021)
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease
Yingyue Zhou et al.
NATURE MEDICINE (2020)
A Toll-receptor map underlies structural brain plasticity
Guiyi Li et al.
ELIFE (2020)
Disease-associated astrocytes in Alzheimer's disease and aging
Naomi Habib et al.
NATURE NEUROSCIENCE (2020)
Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity
Phi T. Nguyen et al.
CELL (2020)
A scalable SCENIC workflow for single-cell gene regulatory network analysis
Bram van de Sande et al.
NATURE PROTOCOLS (2020)
Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium
Rebekah Mahoney et al.
CELL REPORTS (2020)
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
Ying-Wooi Wan et al.
CELL REPORTS (2020)
Integrated analysis of the aging brain transcriptome and proteome in tauopathy
Carl Grant Mangleburg et al.
MOLECULAR NEURODEGENERATION (2020)
Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer's disease
Shun-Fat Lau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
The relationship between the morphological subtypes of microglia and Alzheimer's disease neuropathology
Patrick Jarmo Paasila et al.
BRAIN PATHOLOGY (2019)
Single-cell transcriptomic analysis of Alzheimer's disease
Hansruedi Mathys et al.
NATURE (2019)
g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)
Uku Raudvere et al.
NUCLEIC ACIDS RESEARCH (2019)
DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
Christopher S. McGinnis et al.
CELL SYSTEMS (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
The basis of cellular and regional vulnerability in Alzheimer's disease
Dunja Mrdjen et al.
ACTA NEUROPATHOLOGICA (2019)
Microglia in Brain Development, Homeostasis, and Neurodegeneration
Christopher J. Bohlen et al.
Annual Review of Genetics (2019)
The neuropathological diagnosis of Alzheimer's disease
Michael A. DeTure et al.
MOLECULAR NEURODEGENERATION (2019)
Ageing as a risk factor for neurodegenerative disease
Yujun Hou et al.
NATURE REVIEWS NEUROLOGY (2019)
A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation
Alexandra Grubman et al.
NATURE NEUROSCIENCE (2019)
Glial Phagocytic Receptors Promote Neuronal Loss in Adult Drosophila Brain
Ketty Hakim-Mishnaevski et al.
CELL REPORTS (2019)
Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
Xuran Wang et al.
NATURE COMMUNICATIONS (2019)
A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo
Farah H. Bardai et al.
JOURNAL OF NEUROSCIENCE (2018)
Phenotypic Convergence: Distinct Transcription Factors Regulate Common Terminal Features
Nikolaos Konstantinides et al.
CELL (2018)
A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain
Kristofer Davie et al.
CELL (2018)
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
Aleksandra Deczkowska et al.
CELL (2018)
scmap: projection of single-cell RNA -seq data across data sets
Vladimir Yu Kiselev et al.
NATURE METHODS (2018)
Tau Activates Transposable Elements in Alzheimer's Disease
Caiwei Guo et al.
CELL REPORTS (2018)
Selective vulnerability in neurodegenerative diseases
Hongjun Fu et al.
NATURE NEUROSCIENCE (2018)
Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease
Danielle S. Davies et al.
BRAIN PATHOLOGY (2017)
FlyBase at 25: looking to the future
L. Sian Gramates et al.
NUCLEIC ACIDS RESEARCH (2017)
The Glia of the Adult Drosophila Nervous System
Malte C. Kremer et al.
GLIA (2017)
Glial contributions to neurodegeneration in tauopathies
Cheryl E. G. Leyns et al.
MOLECULAR NEURODEGENERATION (2017)
NF-κB Immunity in the Brain Determines Fly Lifespan in Healthy Aging and Age-Related Neurodegeneration
Ilias Kounatidis et al.
CELL REPORTS (2017)
Impact of multiple pathologies on the threshold for clinically overt dementia
Alifiya Kapasi et al.
ACTA NEUROPATHOLOGICA (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?
Kendra E. Hargis et al.
BEHAVIOURAL BRAIN RESEARCH (2017)
The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases
Jochen Walter
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease
Amit K. Chouhan et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2016)
First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression
Damian M. Cummings et al.
BRAIN (2015)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
CELL (2015)
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease
Elizabeta Gjoneska et al.
NATURE (2015)
Drosophila Central Nervous System Glia
Marc R. Freeman
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology
Mar Matarin et al.
CELL REPORTS (2015)
Alzheimer's disease
Colin L. Masters et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
Greg Finak et al.
GENOME BIOLOGY (2015)
The Drosophila Imd Signaling Pathway
Henna Myllymaki et al.
JOURNAL OF IMMUNOLOGY (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease
Alberto Serrano-Pozo et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
The Innate Immune Response Transcription Factor Relish Is Necessary for Neurodegeneration in a Drosophila Model of Ataxia-Telangiectasia
Andrew J. Petersen et al.
GENETICS (2013)
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study
Victor L. Villemagne et al.
LANCET NEUROLOGY (2013)
Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
Hyelim Cho et al.
NATURE MEDICINE (2013)
WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013
Jing Wang et al.
NUCLEIC ACIDS RESEARCH (2013)
Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain
Yang Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Age-dependent dysregulation of innate immunity
Albert C. Shaw et al.
NATURE REVIEWS IMMUNOLOGY (2013)
ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila
Andrew J. Petersen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
An integrative approach to ortholog prediction for disease-focused and other functional studies
Yanhui Hu et al.
BMC BIOINFORMATICS (2011)
The Drosophila Toll Signaling Pathway
Susanna Valanne et al.
JOURNAL OF IMMUNOLOGY (2011)
Regulation of neural process growth, elaboration and structural plasticity by NF-κB
Humberto Gutierrez et al.
TRENDS IN NEUROSCIENCES (2011)
Toll-like receptor signaling in neural plasticity and disease
Eitan Okun et al.
TRENDS IN NEUROSCIENCES (2011)
Differential Effects of Tau on the Integrity and Function of Neurons Essential for Learning in Drosophila
Stylianos Kosmidis et al.
JOURNAL OF NEUROSCIENCE (2010)
Regularization Paths for Generalized Linear Models via Coordinate Descent
Jerome Friedman et al.
JOURNAL OF STATISTICAL SOFTWARE (2010)
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
Martin Fuhrmann et al.
NATURE NEUROSCIENCE (2010)
Ensheathing Glia Function as Phagocytes in the Adult Drosophila Brain
Johnna Doherty et al.
JOURNAL OF NEUROSCIENCE (2009)
Organization and Postembryonic Development of Glial Cells in the Adult Central Brain of Drosophila
Takeshi Awasaki et al.
JOURNAL OF NEUROSCIENCE (2008)
Building Predictive Models in R Using the caret Package
Max Kuhn
JOURNAL OF STATISTICAL SOFTWARE (2008)
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
Terrence Town et al.
NATURE MEDICINE (2008)
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
Sung-Chun Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
NF-κB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling
B Kaltschmidt et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons
A Mershin et al.
LEARNING & MEMORY (2004)
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway
S Lehnardt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Tauopathy in Drosophila:: Neurodegeneration without neurofibrillary tangles
CW Wittmann et al.
SCIENCE (2001)