4.8 Article

Proliferative exhausted CD8+ T cells exacerbate long-lasting anti-tumor effects in human papillomavirus-positive head and neck squamous cell carcinoma

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemical Research Methods

Nebulosa recovers single-cell gene expression signals by kernel density estimation

Jose Alquicira-Hernandez et al.

Summary: Nebulosa is an R package that utilizes weighted kernel density estimation to recover lost signals caused by data sparsity in single-cell experiments, improving the accurate assessment of gene expression.

BIOINFORMATICS (2021)

Article Oncology

Palbociclib and cetuximab in cetuximab-resistant human papillomavirus-related oropharynx squamous-cell carcinoma: A multicenter phase 2 trial

Peter Oppelt et al.

Summary: The study aimed to evaluate the efficacy of palbociclib and cetuximab combination therapy in HPV-related oropharyngeal cancer, but only one patient achieved an objective response, with disease progression in most patients, indicating the treatment's limited effectiveness.

ORAL ONCOLOGY (2021)

Article Multidisciplinary Sciences

Inference and analysis of cell-cell communication using CellChat

Suoqin Jin et al.

Summary: By constructing an interaction database and developing the tool CellChat, the authors quantitatively inferred and analyzed cell-cell communication networks, revealing important signaling inputs and outputs between cells, and achieved classification of conserved and context-specific pathways.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

Mayura Wagle et al.

Summary: Chronic antigenic stimulation induces the expression of EGR2, which in turn affects the epigenetic and transcriptional identity of exhausted T cells.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Integrated analysis of multimodal single-cell data

Yuhan Hao et al.

Summary: The study introduces a weighted-nearest neighbor analysis framework to learn the relative utility of each data type in each cell, enabling integrative analysis of multiple modalities. Applied to a CITE-seq dataset, the method constructs a multimodal reference atlas of the circulating immune system and successfully identifies and validates previously unreported lymphoid subpopulations.
Article Multidisciplinary Sciences

clusterProfiler 4.0: A universal enrichment tool for interpreting omics data

Tianzhi Wu et al.

Summary: The updated version of clusterProfiler 4.0 is a powerful tool for functional enrichment analysis in a wide range of organisms, offering tidy interfaces for data operation and visualization, as well as new features like gene set enrichment analysis and comparison of results from multiple gene lists.

INNOVATION (2021)

Review Oncology

Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition

Monica Alvarez-Fernandez et al.

CANCER CELL (2020)

Review Biochemistry & Molecular Biology

Recent insights of T cell receptor-mediated signaling pathways for T cell activation and development

Jeong-Ryul Hwang et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

Review Oncology

The application and prospect of CDK4/6 inhibitors in malignant solid tumors

Qi Du et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)

Article Cell Biology

Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1

Jesus Romero-Pozuelo et al.

CELL REPORTS (2020)

Review Biochemistry & Molecular Biology

Integrating Old and New Paradigms of G1/S Control

Seth M. Rubin et al.

MOLECULAR CELL (2020)

Review Immunology

Re-defining T-Cell Exhaustion: Subset, Function, and Regulation

Se Jin Im et al.

IMMUNE NETWORK (2020)

Article Multidisciplinary Sciences

The single-cell transcriptional landscape of mammalian organogenesis

Junyue Cao et al.

NATURE (2019)

Article Biochemical Research Methods

Fast, sensitive and accurate integration of single-cell data with Harmony

Ilya Korsunsky et al.

NATURE METHODS (2019)

Article Oncology

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

J. Ferlay et al.

INTERNATIONAL JOURNAL OF CANCER (2019)

Article Multidisciplinary Sciences

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells

Caroline S. Jansen et al.

NATURE (2019)

Article Immunology

Defining 'T cell exhaustion'

Christian U. Blank et al.

NATURE REVIEWS IMMUNOLOGY (2019)

Article Biochemistry & Molecular Biology

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

Elham Azizi et al.

Review Cell Biology

CDK4/6 Inhibition in Cancer: Beyond Cell Cycle Arrest

Shom Goel et al.

TRENDS IN CELL BIOLOGY (2018)

Article Biochemical Research Methods

SCENIC: single-cell regulatory network inference and clustering

Sara Aibar et al.

NATURE METHODS (2017)

Article Multidisciplinary Sciences

Massively parallel digital transcriptional profiling of single cells

Grace X. Y. Zheng et al.

NATURE COMMUNICATIONS (2017)

Article Biochemical Research Methods

destiny: diffusion maps for large-scale single cell data in R

Philipp Angerer et al.

BIOINFORMATICS (2016)

Article Multidisciplinary Sciences

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

Se Jin Im et al.

NATURE (2016)

Review Immunology

Molecular and cellular insights into T cell exhaustion

E. John Wherry et al.

NATURE REVIEWS IMMUNOLOGY (2015)

Review Cell Biology

Control of cell cycle transcription during G1 and S phases

Cosetta Bertoli et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Otorhinolaryngology

Correlation of Cellular Immunity With Human Papillomavirus 16 Status and Outcome in Patients With Advanced Oropharyngeal Cancer

Derrick Wansom et al.

ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY (2010)

Article Medicine, General & Internal

Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

K. Kian Ang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)