期刊
ASIAN JOURNAL OF ORGANIC CHEMISTRY
卷 12, 期 6, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.202300237
关键词
-
In this study, a simple, practical, and catalytic methodology for the N-formylation of various amines using iron as a catalyst was developed. This protocol features an inexpensive iron catalyst, short reaction time, mild reaction conditions, good yields, easy workup, and tolerance of a wide variety of functional groups.
In organic synthesis, formamides are the most abundant class of compounds owing to their importance as the building blocks in synthetic and industrial organic chemistry. Formamides are also one of the most valuable intermediates produced in drug synthesis and act as precursors for the synthesis of therapeutically-relevant molecules. Here, we developed a simple, practical, and catalytic methodology for the N-formylation of a wide variety of amines by using iron as a catalyst. This protocol features an inexpensive iron catalyst, short reaction time, mild reaction conditions, good yields, easy workup, and tolerance of a wide variety of functional groups.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据