Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications

The past 20 years of research has elucidated new innate immune sensing and cell death pathways with disease relevance. Future molecular characterization of these pathways and their crosstalk and functional redundancies will aid in development of therapeutic strategies.

Automated summary

The past two decades of research have revealed new innate immune sensing and cell death pathways that are relevant to diseases. Further molecular characterization of these pathways and understanding their crosstalk and functional redundancies will contribute to the development of therapeutic strategies.