☆ 4.4 Article

Bacterial communities in the nasal passage of postviral olfactory dysfunction patients

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2023)

A dysbiotic microbiome promotes head and neck squamous cell carcinoma

Daniel N. Frank et al.

Summary: Recent studies have found dysbiotic oral microbiota and tumor-resident bacteria in patients with HNSCC, with elevated levels of Lactobacillus spp. and reduced levels of Neisseria spp. Furthermore, experimental evidence shows that depletion of microbiota delays oral tumorigenesis, while transfer of microbiota from mice with oral cancer accelerates tumorigenesis. These findings support the hypothesis that dysbiosis promotes HNSCC development.

ONCOGENE (2022)

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Article Cell Biology

COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

Guilherme Dias de Melo et al.

Summary: Recent investigations have shown that olfactory and taste dysfunction are common in mildly symptomatic COVID-19 patients. Research on the olfactory neuroepithelium revealed that SARS-CoV-2 infection can cause local inflammation and lead to acute loss of smell, which may account for prolonged symptoms of COVID-19 such as anosmia.

SCIENCE TRANSLATIONAL MEDICINE (2021)

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Article Multidisciplinary Sciences