☆ 4.6 Review

An update on mobile applications collecting data among subjects with or at risk of Alzheimer's disease

FRONTIERS IN AGING NEUROSCIENCE (2023)

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Article Clinical Neurology

Global estimates on the number of persons across the Alzheimer's disease continuum

Anders Gustavsson et al.

Summary: This study synthesized literature on the prevalence of Alzheimer's disease (AD) at different stages and estimated the global number of individuals in the early stages of AD. The findings revealed that there are approximately 320 million individuals with AD dementia, 690 million with prodromal AD, and 315 million with preclinical AD globally. Together, these individuals constitute 22% of the population aged 50 and above. However, uncertainties remain in these estimates, particularly in low- and middle-income regions where biomarker studies are lacking.

ALZHEIMERS & DEMENTIA (2023)

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Article Neurosciences

Remind Me To Remember: A pilot study of a novel smartphone reminder application for older adults with dementia and mild cognitive impairment

Katherine Hackett et al.

Summary: This pilot study examined the feasibility and efficacy of the smartphone-based reminder application SmartPrompt in reducing functional disability in older adults with cognitive difficulties. The results showed promise for the use of SmartPrompt in at-home contexts.

NEUROPSYCHOLOGICAL REHABILITATION (2022)

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Article Health Care Sciences & Services

Quality of Mobile Apps for Care Partners of People With Alzheimer Disease and Related Dementias: Mobile App Rating Scale Evaluation

Nicole E. Werner et al.

Summary: This study evaluates the quality of publicly available apps for care partners of people living with Alzheimer disease and related dementias (ADRD) and identifies the design features of low- and high-quality apps. The results show that the average quality of these apps is minimally acceptable, with many apps having broken features and low scores for engagement and information. Meeting the minimum acceptable quality might not be sufficient to meet the needs of care partners.

JMIR MHEALTH AND UHEALTH (2022)

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Article Health Care Sciences & Services

Co-design of a Smartphone App for People Living With Dementia by Applying Agile, Iterative Co-design Principles: Development and Usability Study

Sarah Fox et al.

Summary: This study explores the benefits of co-design in the development of smartphone apps. Using Agile methodology and continuous user consultation, testing, and feedback, individuals living with dementia and their care partners were actively involved in co-designing an easy-to-use, accessible, and appealing mobile health app. Co-design resulted in multiple patient and care partner-led software alterations, improving the user-friendliness and acceptability of the product.

JMIR MHEALTH AND UHEALTH (2022)

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Article Public, Environmental & Occupational Health

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease 2019

Emma Nichols et al.

Summary: With projected trends in population ageing and growth, the number of people with dementia is expected to increase. Understanding the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritization, with a focus on potentially modifiable risk factors.

LANCET PUBLIC HEALTH (2022)

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Review Rehabilitation

Mobile apps for dementia awareness, support, and prevention - review and evaluation

Georgina R. Chelberg et al.

Summary: The majority of dementia apps are free and primarily targeted towards caregivers, focusing on dementia information and practical tips. However, there is limited language options and ongoing support available in these apps, with few apps scoring well on Overall Quality according to MARS appraisal.

DISABILITY AND REHABILITATION (2022)

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Article Medicine, General & Internal

Digital biomarkers and sex impacts in Alzheimer's disease management - potential utility for innovative 3P medicine approach

Robbert L. Harms et al.

Summary: Digital biomarkers, which are objective and quantifiable physiological and behavioral data collected by digital devices, have revolutionized clinical research by enabling high-frequency and sensitive measurements. In the field of neurodegenerative diseases, a digital biomarker-based technology called instrumental activities of daily living (iADL) digital medical application has proved to be a predictive biomarker for the conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) dementia. However, the use of digital biomarkers can be influenced by variables such as demographics, genetics, and phenotype. In this study, sex differences were explored in Altoida's digital medical application, and it was found that there were significant differences in neurocognitive performance signatures between males and females, indicating the importance of integrating traditional approaches with digital biomarker technologies in dementia research.

EPMA JOURNAL (2022)

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Proceedings Paper Computer Science, Interdisciplinary Applications

Alzheimer's Disease and Mild Cognitive Impairment Serious Games: A Systematic Analysis in Smartphone Application Markets

Farveh Sabermahani et al.

Summary: This study aimed to determine the cognitive aspects supported by available cognitive games by searching online application markets. The majority of the identified games were found suitable for assessing attention and orientation, but most of them lack research on their impact on elderly individuals with cognitive impairment.

DHEALTH 2022-PROCEEDINGS OF THE 16TH HEALTH INFORMATICS MEETS DIGITAL HEALTH CONFERENCE (2022)

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Article Clinical Neurology

The Functionality, Evidence, and Privacy Issues Around Smartphone Apps for the Top Neuropsychiatric Conditions

Mia T. Minen et al.

Summary: This study investigated the market of smartphone apps targeting five most disabling neuropsychiatric conditions, finding that most apps focused on migraine, depression, and anxiety with interventions, though many interventions lacked evidence-based support. Furthermore, while most apps had privacy policies, lay people may struggle to comprehend these policies due to their complexity.

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES (2021)

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Article Geriatrics & Gerontology

Effectiveness of App-Based Cognitive Screening for Dementia by Lay Health Workers in Low Resource Settings. A Validation and Feasibility Study in Rural Tanzania

Stella-Maria Paddick et al.

Summary: This study evaluated the diagnostic accuracy of a brief dementia screening mobile application in rural Tanzania, finding good sensitivity but lacking specificity when administered by non-specialist workers. This technological approach may be a promising way forward in low-resource settings, with specialist onward referral potentially prioritized.

JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY (2021)

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Article Neurosciences

GEORGE®: A Pilot Study of a Smartphone Application for Huntington's Disease

Emma M. Waddell et al.

Summary: The study demonstrated the feasibility of using the smartphone application GEORGE for Huntington's disease, showing its effectiveness in differentiating HD patients from non-patients and measuring key disease features. Further refinement of the application's interface and activities could enhance its usability and sensitivity for clinical care and research purposes.

JOURNAL OF HUNTINGTONS DISEASE (2021)

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Article Chemistry, Analytical

DailyCog: A Real-World Functional Cognitive Mobile Application for Evaluating Mild Cognitive Impairment (MCI) in Parkinson's Disease

Sara Rosenblum et al.

Summary: Parkinson's disease is the second most common progressive neurodegenerative disorder that affects patient functioning and quality of life, with cognitive impairment having a significant impact on emotional and physical health. DailyCog is a smartphone application developed for the detection of mild cognitive impairment, utilizing a simulated environment of daily tasks and self-report questionnaires to assess cognitive levels in patients. Usability studies showed that most users were able to use the app with ease, providing valuable insights into cognitive function assessment.

SENSORS (2021)

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Article Geriatrics & Gerontology

Mobile application for monitoring behavioral and psychological symptoms of dementia in patients with moderate to severe dementia

Poonsri Rangseekajee et al.

Summary: The study developed a mobile application for caregivers to monitor behavioral and psychological symptoms of dementia in patients with moderate-severe dementia, showing excellent sensitivity, good-very good validity, and consistency. The caregivers had a positive perception of the application as an aid in caregiving.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2021)

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Article Health Care Sciences & Services

Digital reminiscence app co-created by people living with dementia and carers: Usability and eye gaze analysis

Kyle Boyd et al.

Summary: This study examined the usability of a reminiscence app named 'InspireD' using eye tracking technology. The results showed that using a wearable eye tracker in this setting had no barriers, but some tasks required prompts from observers. People living with dementia had fewer gaze fixations on the app compared to their carers, indicating that they take more time to consume information.

HEALTH EXPECTATIONS (2021)

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Editorial Material Biochemistry & Molecular Biology

Editorial: Designing a Protocol Adopting an Artificial Intelligence (AI)-Driven Approach for Early Diagnosis of Late-Onset Alzheimer's Disease

Victor O. K. Li et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2021)

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Article Medicine, General & Internal

Prevention of dementia using mobile phone applications (PRODEMOS): protocol for an international randomised controlled trial

Esmé Eggink et al.

BMJ Open (2021)

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Review Computer Science, Information Systems

An Overview of Existing Publications and Most Relevant Projects/Platforms on the Use of Blockchain in Medicine and Neurology

Jakub Hort et al.

Summary: This article reviews the use of blockchain technology in Medicine and Neurology, highlighting the benefits and potential applications in healthcare. While there are numerous projects related to health care, disease prevention, and healthy lifestyle promotion in medicine, Neurology only has one promising ongoing project. The discussion points out the lack of patient clinical history information as a problem in medicine and suggests that blockchain technology can help with patient management, treatment monitoring, and clinical trial standardization.

FRONTIERS IN BLOCKCHAIN (2021)

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Review Computer Science, Interdisciplinary Applications

In Quest of Tablet Apps for Elders With Alzheimer's Disease A Descriptive Review

Sunghee H. Tak

Summary: This review article discusses the current state of tablet apps available for elders with Alzheimer's disease and related forms of dementia, finding that most game apps require high cognitive and physical abilities. Due to individual variability in cognitive and functional abilities, a person-centered approach is necessary in designing and selecting games and activities for apps in order to increase engagement and promote positive experiences in older adults.

CIN-COMPUTERS INFORMATICS NURSING (2021)

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Article Health Care Sciences & Services

Evaluating the Feasibility of Frequent Cognitive Assessment Using the Mezurio Smartphone App: Observational and Interview Study in Adults With Elevated Dementia Risk

Claire Lancaster et al.

JMIR MHEALTH AND UHEALTH (2020)

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Review Health Care Sciences & Services

Mobile health applications for people with dementia: a systematic review and synthesis of qualitative studies

Andrew Brown et al.

INFORMATICS FOR HEALTH & SOCIAL CARE (2020)

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Review Medicine, General & Internal

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

Gill Livingston et al.

LANCET (2020)

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News Item Multidisciplinary Sciences

ALEXA, DO I HAVE COVID-19?

Emily Anthes

NATURE (2020)

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Review Computer Science, Interdisciplinary Applications

Dementia medical screening using mobile applications: A systematic review with a new mapping model

Fadi Thabtah et al.

JOURNAL OF BIOMEDICAL INFORMATICS (2020)

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Article Health Policy & Services

A comprehensive study of mobile-health based assistive technology for the healthcare of dementia and Alzheimer's disease (AD)

Kanwal Yousaf et al.

HEALTH CARE MANAGEMENT SCIENCE (2020)

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Review Clinical Neurology

Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting

Marwan N. Sabbagh et al.

JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE (2020)

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Article Geriatrics & Gerontology

Existing Mobile Phone Apps for Self-Care Management of People With Alzheimer Disease and Related Dementias: Systematic Analysis

Yuqi Guo et al.

JMIR AGING (2020)

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Article Engineering, Biomedical

Mobility assessment in people with Alzheimer disease using smartphone sensors

Pilar Serra-Ano et al.

JOURNAL OF NEUROENGINEERING AND REHABILITATION (2019)

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Article Computer Science, Information Systems

Design and evaluation of a mobile application for monitoring patients with Alzheimer's disease: A day center case study

Alma Chavez et al.

INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS (2019)

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Article Health Care Sciences & Services

A Mobile-Based Screening System for Data Analyses of Early Dementia Traits Detection

Fadi Thabtah et al.

JOURNAL OF MEDICAL SYSTEMS (2019)

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Article Geriatrics & Gerontology

The Value of Including People with Dementia in the Co-Design of Personalized eHealth Technologies

Cristian Leorin et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2019)

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Article Biochemical Research Methods

Extended, continuous measures of functional status in community dwelling persons with Alzheimer's and related dementia: Infrastructure, performance, tradeoffs, preliminary data, and promise

Bradley Zylstra et al.

JOURNAL OF NEUROSCIENCE METHODS (2018)

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Article Geriatrics & Gerontology

Diagnostic test accuracy of a novel smartphone application for the assessment of attention deficits in delirium in older hospitalised patients: a prospective cohort study protocol

Lisa-Marie Rutter et al.

BMC GERIATRICS (2018)

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Article Medical Informatics

Characterizing patient compliance over six months in remote digital trials of Parkinson's and Huntington disease

Shani Cohen et al.

BMC MEDICAL INFORMATICS AND DECISION MAKING (2018)

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Review Psychiatry

Digital technologies for the assessment of cognition: a clinical review

Amy Chinner et al.

EVIDENCE-BASED MENTAL HEALTH (2018)

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Proceedings Paper Computer Science, Information Systems

A Structured Analysis of Smartphone Applications to Early Diagnose Alzheimer's Disease or Dementia

Nina Polzer et al.

8TH INTERNATIONAL CONFERENCE ON EMERGING UBIQUITOUS SYSTEMS AND PERVASIVE NETWORKS (EUSPN 2017) / 7TH INTERNATIONAL CONFERENCE ON CURRENT AND FUTURE TRENDS OF INFORMATION AND COMMUNICATION TECHNOLOGIES IN HEALTHCARE (ICTH-2017) / AFFILIATED WORKSHOPS (2017)

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Article Geriatrics & Gerontology

Data Security and Privacy in Apps for Dementia: An Analysis of Existing Privacy Policies

Lisa Rosenfeld et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2017)

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Article Computer Science, Interdisciplinary Applications

A mobile application for cognitive screening of dementia

Gokhan Zorluoglu et al.

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2015)

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Article Psychology, Clinical

Development of a smartphone application for the objective detection of attentional deficits in delirium

Zoe Tieges et al.

INTERNATIONAL PSYCHOGERIATRICS (2015)

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Review Medical Informatics

A Systematic Review of Healthcare Applications for Smartphones

Abu Saleh Mohammad Mosa et al.

BMC MEDICAL INFORMATICS AND DECISION MAKING (2012)

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