Survival benefit of adjuvant transcatheter arterial chemoembolization for patients with hepatocellular carcinoma after anatomical hepatectomy

Article Surgery

Short- and long-term outcomes of laparoscopic versus open liver resection for large hepatocellular carcinoma: a propensity score study

Kang-Jun Zhang et al.

Summary: There were no significant differences in perioperative complications or long-term prognosis between laparoscopic and open liver resection for large HCC.

SURGERY TODAY (2023)

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Article Surgery

Indocyanine green fluorescence imaging-guided laparoscopic right posterior hepatectomy

Jinghua Li et al.

Summary: The study evaluated the safety and effectiveness of ICG fluorescence imaging-guided laparoscopic right posterior hepatectomy, showing that ICG fluorescence imaging guidance could be helpful for the safe implementation of the surgery.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2022)

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Article Oncology

Anatomic Resection for Hepatocellular Carcinoma: Prognostic Impact Assessed from Recurrence Treatment

Masaaki Minagawa et al.

Summary: Anatomic resection (AR) reduces recurrence in primary HCC surgery, but does not significantly affect 5-year overall survival rates between the two groups. Non-anatomic resection (NAR) patients are more likely to undergo curative repeat resection or ablation therapy compared to AR patients.

ANNALS OF SURGICAL ONCOLOGY (2022)

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Article Gastroenterology & Hepatology

Lung and lymph node metastases from hepatocellular carcinoma: Comparison of pathological aspects

Ha Young Woo et al.

Summary: Metastatic HCCs to various organs exhibit different pathological characteristics, with VETC and MTM subtypes associated with lung metastases, and K19 expression, EMT-high features, fibrous tumor stroma, and high immune cell infiltration linked to lymph node metastases.

LIVER INTERNATIONAL (2022)

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Article Surgery

Laparoscopic Anatomical Versus Non-anatomical hepatectomy in the Treatment of Hepatocellular Carcinoma: A randomised controlled trial

Kexi Liao et al.

Summary: Comparing laparoscopic anatomical hepatectomy (LAH) and non-anatomical hepatectomy (LNAH) for hepatocellular carcinoma (HCC), LAH was found to have higher disease-free survival (DFS), lower intrahepatic ipsilateral recurrence rate, comparable long-term overall survival (OS), and similar postoperative complications for selected HCC patients.

INTERNATIONAL JOURNAL OF SURGERY (2022)

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Review Integrative & Complementary Medicine

Traditional Chinese medicine for prevention and treatment of hepatocellular carcinoma: A focus on epithelial-mesenchymal transition

Jia-jia Li et al.

Summary: Hepatocellular carcinoma is a prevalent malignant cancer globally, and the epithelial-mesenchymal transition plays a crucial role in early metastasis. Traditional Chinese medicines have been recognized for their inhibitory effects on HCC, but research on their impact on EMT in HCC is limited and requires further investigation.

JOURNAL OF INTEGRATIVE MEDICINE-JIM (2021)

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Article Medicine, General & Internal

Hepatocellular carcinoma

Josep M. Llovet et al.

Summary: Liver cancer, particularly hepatocellular carcinoma (HCC), poses a significant global health challenge with rising incidence projected to exceed 1 million cases by 2025. Infection by hepatitis B and C viruses remains a major risk factor for HCC, while non-alcoholic steatohepatitis is emerging as a more common risk factor in Western countries. Advances in systemic therapies for HCC, including immunotherapies and targeted therapies, are expected to revolutionize the management of this disease.

NATURE REVIEWS DISEASE PRIMERS (2021)

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Letter Oncology

Development and validation of a novel online calculator for estimating survival benefit of adjuvant transcatheter arterial chemoembolization in patients undergoing surgery for hepatocellular carcinoma

Lei Liang et al.

Summary: This study constructed an online calculator for assessing the survival benefit of adjuvant TACE for patients with resected HCC based on large-scale real-world data. By incorporating existing independent survival predictors, two prediction models were successfully developed and showed good calibration and discrimination.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

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Article Gastroenterology & Hepatology