4.8 Article

A posttranscriptional pathway regulates cell wall mRNA expression in budding yeast

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Control of Gene Expression via the Yeast CWI Pathway

Ana Belen Sanz et al.

Summary: Living cells can activate cellular responses to ensure maximum cell survival when facing stressful environmental conditions. The regulation of gene expression by mitogen-activated protein kinase (MAPK) cascades, particularly in the yeast Saccharomyces cerevisiae, plays a critical role in these cellular responses, particularly in the context of cell wall damage. Understanding the molecular mechanisms by which MAPKs control gene expression can potentially lead to the identification of novel therapeutic targets.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Biochemistry & Molecular Biology

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

Mihaly Varadi et al.

Summary: AlphaFold DB is an openly accessible database with high-accuracy protein-structure predictions, powered by DeepMind's AlphaFold v2.0. It provides programmatic access to a vast number of predicted structures and is expanding to cover more sequences.

NUCLEIC ACIDS RESEARCH (2022)

Article Biochemistry & Molecular Biology

Echinocandins - structure, mechanism of action and use in antifungal therapy

Mateusz Szymanski et al.

Summary: Echinocandins inhibit fungal cell wall synthesis by targeting beta-(1,3)-D-glucan, offering potential for novel derivatives with improved pharmacological properties. These drugs show promise in more effectively treating infections caused by Candida and Aspergillus species.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2022)

Article Biochemistry & Molecular Biology

Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition site

Rosemary A. Bayne et al.

Summary: Ssd1, a conserved fungal RNA-binding protein, plays important roles in stress responses, cell division, and virulence. Through in vivo cross-linking and cDNA analysis, precise binding sites of Ssd1 on RNA were identified, particularly enriched in the 5' untranslated regions of mRNAs encoding cell wall proteins. The structure-guided mutations of Ssd1 prevent its binding to RNA, providing insights into the evolution of regulatory elements in the RNase II family.

NUCLEIC ACIDS RESEARCH (2022)

Article

Post-transcriptional control of fungal cell wall synthesis

Rebecca A. Hall et al.

Cell Surface (2022)

Article Genetics & Heredity

Dynamic post-transcriptional regulation by Mrn1 links cell wall homeostasis to mitochondrial structure and function

Kendra Reynaud et al.

Summary: The yeast RNA-binding protein Mrn1 is involved in controlling a gene expression program that links mitochondria with the yeast cell wall, impacting cell wall organization and biogenesis. Mrn1 destabilizes target mRNAs during glucose fermentation, but this repression is relieved when cells switch to respiratory growth, leading to expanded mitochondria and quicker adaptation to respiration in cells lacking MRN1. The SUN domain protein Nca3, a key target of Mrn1, plays a crucial role in sculpting mitochondria and the cell wall in response to changing growth conditions.

PLOS GENETICS (2021)

Article Multidisciplinary Sciences

Highly accurate protein structure prediction with AlphaFold

John Jumper et al.

Summary: Proteins are essential for life, and accurate prediction of their structures is a crucial research problem. Current experimental methods are time-consuming, highlighting the need for accurate computational approaches to address the gap in structural coverage. Despite recent progress, existing methods fall short of atomic accuracy in protein structure prediction.

NATURE (2021)

Article Biochemistry & Molecular Biology

Stress-Induced Translation Inhibition through Rapid Displacement of Scanning Initiation Factors

Stefan Bresson et al.

MOLECULAR CELL (2020)

Article Biochemistry & Molecular Biology

Defining the RNA interactome by total RNA-associated protein purification

Vadim Shchepachev et al.

MOLECULAR SYSTEMS BIOLOGY (2019)

Review Microbiology

Recent Insights into the Paradoxical Effect of Echinocandins

Johannes Wagener et al.

JOURNAL OF FUNGI (2018)

Article Microbiology

The Fungal Cell Wall: Structure, Biosynthesis, and Function

Neil A. R. Gow et al.

MICROBIOLOGY SPECTRUM (2017)

Article Multidisciplinary Sciences

A global genetic interaction network maps a wiring diagram of cellular function

Michael Costanzo et al.

SCIENCE (2016)

Article Biotechnology & Applied Microbiology

Genomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature

Raul Garcia et al.

BMC GENOMICS (2015)

Review Biochemistry & Molecular Biology

Membrane Trafficking in the Yeast Saccharomyces cerevisiae Model

Serge Feyder et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Article Biochemistry & Molecular Biology

New vectors for simple and streamlined CRISPR-Cas9 genome editing in Saccharomyces cerevisiae

Marian F. Laughery et al.

Article Biochemical Research Methods

A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly

Michael E. Lee et al.

ACS SYNTHETIC BIOLOGY (2015)

Article Multidisciplinary Sciences

Visual account of protein investment in cellular functions

Wolfram Liebermeister et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Biochemistry & Molecular Biology

A Transcriptome-wide Atlas of RNP Composition Reveals Diverse Classes of mRNAs and lncRNAs

Alex Charles Tuck et al.

Review Microbiology

Biogenesis of the Saccharomyces cerevisiae Pheromone a-Factor, from Yeast Mating to Human Disease

Susan Michaelis et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2012)

Letter Biotechnology & Applied Microbiology

Integrative genomics viewer

James T. Robinson et al.

NATURE BIOTECHNOLOGY (2011)

Article Biochemical Research Methods

BEDTools: a flexible suite of utilities for comparing genomic features

Aaron R. Quinlan et al.

BIOINFORMATICS (2010)

Article Biochemical Research Methods

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

Eran Eden et al.

BMC BIOINFORMATICS (2009)

Article Biochemistry & Molecular Biology

Cbk1 Regulation of the RNA-Binding Protein Ssd1 Integrates Cell Fate with Translational Control

Jaclyn M. Jansen et al.

CURRENT BIOLOGY (2009)

Article Multidisciplinary Sciences

Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs

Sander Granneman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Cell Biology

Plasma membrane microdomains regulate turnover of transport proteins in yeast

Guido Grossmann et al.

JOURNAL OF CELL BIOLOGY (2008)

Article Biophysics

Single-spanning membrane protein insertion in membrane mimetic systems:: role and localization of aromatic residues

YM Coïc et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2005)

Article Biochemistry & Molecular Biology

Expression and subcellular localization of a membrane protein related to Hsp30p in Saccharomyces cerevisiae

K Wu et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2000)