☆ 4.8 Article

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein

CELL REPORTS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Immunology

Transfusion-Transmitted Cache Valley Virus Infection in a Kidney Transplant Recipient With Meningoencephalitis

Omar Al-Heeti et al.

Summary: This study identified a case of Cache Valley virus infection transmitted through blood transfusion and emphasized the consideration of arboviral infections in patients with meningoencephalitis after blood transfusion or organ transplantation. The use of metagenomic next-generation sequencing can facilitate the preliminary diagnosis of rare, unexpected infections, particularly in immunocompromised patients.

CLINICAL INFECTIOUS DISEASES (2023)

添加到收藏夹

Article Multidisciplinary Sciences

Structure and receptor recognition by the Lassa virus spike complex

Michael Katz et al.

Summary: Lassa virus, a human pathogen, has a spike complex on its surface that facilitates cell entry. The structure of the spike complex reveals the role of the signal peptide in stabilizing the complex and provides insights into the mechanism of binding with the host cell.

NATURE (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies

Akaash K. Mishra et al.

Summary: This study reveals the structure and neutralization mechanism of the Crimean-Congo hemorrhagic fever virus membrane fusion glycoprotein Gc, providing important molecular insights for the development of virus-specific medical countermeasures.

SCIENCE (2022)

添加到收藏夹

Article Immunology

Aedes Albopictus and Cache Valley virus: a new threat for virus transmission in New York State

Constentin Dieme et al.

Summary: This study reports surveillance results of Cache Valley virus in New York State from 2017 to 2020. Anopheles spp. mosquitoes had the highest infection rates, and Aedes albopictus was detected carrying the virus for the first time in the state. The study also found phenotypic variability among different strains and confirmed the vector competence of Ae. albopictus for transmitting the virus.

EMERGING MICROBES & INFECTIONS (2022)

添加到收藏夹

Article Immunology

Encephalitis Caused by Jamestown Canyon Virus in a Liver Transplant Patient, North Carolina, USA, 2017

Emily J. Ciccone et al.

Summary: This is the first documented case of JCV in North Carolina, where a liver transplant patient presented with acute symptoms including headache, aphasia, and confusion. Additionally, it is the first report of successful recovery from JCV encephalitis through treatment with intravenous immune globulin.

OPEN FORUM INFECTIOUS DISEASES (2022)

添加到收藏夹

Article Virology

Targeted Mutations in the Fusion Peptide Region of La Crosse Virus Attenuate Neuroinvasion and Confer Protection against Encephalitis

Bradley S. Hollidge et al.

Summary: La Crosse virus (LACV) is a common pathogen in the United States that causes encephalitis and meningitis. The Gc glycoprotein of LACV plays a crucial role in the neuropathogenesis of encephalitis. The fusion peptide is identified as a determinant of neuroinvasion, but not neurovirulence. Targeting mutations in the fusion peptide could be a potential strategy for live-attenuated virus vaccines.

VIRUSES-BASEL (2022)

添加到收藏夹

Article Microbiology

The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture

Francis R. Hopkins et al.

Summary: Bunyaviruses are emerging RNA viruses that cause significant disease and economic burden and for which vaccines or therapies approved for humans are not available. The bunyavirus genome is wrapped up by the nucleoprotein (NP) and interacts with the viral polymerase, forming a ribonucleoprotein (RNP). This is the only form of the genome active for viral replication and assembly. However, until now how NPs are organized within an RNP was not known for any orthobunyavirus. Here, we purified RNPs from the prototypical orthobunyavirus, Bunyamwera virus, and employed microscopy approaches to show that the NP portion of the RNP was helical. We then combined our helical average with the known structure of an NP monomer, generating a pseudo-atomic model of this region. This arrangement allowed the RNPs to be highly flexible, which was critical for several stages of the viral replication cycle, such as segment circularization.

MBIO (2022)

添加到收藏夹

Article Immunology

Identification of Umbre Orthobunyavirus as a Novel Zoonotic Virus Responsible for Lethal Encephalitis in 2 French Patients with Hypogammaglobulinemia

Philippe Perot et al.

Summary: The study identified Umbre arbovirus in the brain tissue of two immunocompromised patients, representing a previously unidentified orthobunyavirus in humans. In addition, viral sequences related to the virus were found in mosquitoes in southern France, indicating the presence of similar arboviruses in Europe and their potential public health impact.

CLINICAL INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Immunology

Reassortant Cache Valley Virus Associated With Acute Febrile, Nonneurologic Illness, Missouri

Molly Baker et al.

Summary: An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a presumed tickborne illness. His condition deteriorated with respiratory and renal failure, lactic acidosis, and hypotension. Next-generation sequencing and phylogenetic analysis identified a reassortant Cache Valley virus.

CLINICAL INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Microbiology

Co-circulation of Orthobunyaviruses and Rift Valley Fever Virus in Mauritania, 2015

Nicole Cichon et al.

Summary: The study found the co-circulation of at least BUNV and NRIV in Mauritanian sheep and goat populations. Analysis of serum samples revealed the presence of neutralizing reactivity against these viruses and high cross-reactivity among serological assays.

FRONTIERS IN MICROBIOLOGY (2021)

添加到收藏夹

Review Virology

Orthobunyaviruses: From Virus Binding to Penetration into Mammalian Host Cells

Stefan Windhaber et al.

Summary: Orthobunyavirus, the largest genus in the Peribunyaviridae family with over 80 members worldwide, is a structurally simple arthropod-borne virus with a trisegmented, negative-sense RNA genome and only four structural proteins. As potential agents of emerging and re-emerging diseases, OBVs pose a global threat to both public and veterinary health. This review focuses on the initial stages of OBV infection in mammalian hosts, covering virus binding, penetration, and release of the viral genome into the cytosol, and discusses the current understanding of OBV receptors, endocytosis, and fusion.

VIRUSES-BASEL (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

La Crosse Virus Disease in the United States, 2003-2019

Grace M. Vahey et al.

Summary: La Crosse virus is a mosquito-transmitted virus that mainly affects children and causes encephalitis and meningitis. The virus is most commonly reported in the Great Lakes, mid-Atlantic, and southeastern regions of the United States. Surveillance data may underestimate the true incidence of LACV disease.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Highly accurate protein structure prediction with AlphaFold

John Jumper et al.

Summary: Proteins are essential for life, and accurate prediction of their structures is a crucial research problem. Current experimental methods are time-consuming, highlighting the need for accurate computational approaches to address the gap in structural coverage. Despite recent progress, existing methods fall short of atomic accuracy in protein structure prediction.

NATURE (2021)

添加到收藏夹

Article Biology

Characteristics of the 100 largest modern zoonotic disease outbreaks

Patrick R. Stephens et al.

Summary: Zoonotic disease outbreaks pose a significant threat to human health, with various factors contributing to their increasing frequency. Large outbreaks are associated with multiple drivers, including changes in the environment and demographics, with pathogens more likely to be viral and vector-borne. Understanding the characteristics of large outbreaks can provide insights for better surveillance and prevention strategies for zoonotic diseases.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2021)

添加到收藏夹

Article Microbiology

Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice

Sarah Hulsey Stubbs et al.

Summary: Oropouche virus (OROV) infection can lead to severe febrile illness and potentially progress to meningitis or encephalitis. Researchers developed a chimeric vesicular stomatitis virus (VSV) bearing OROV glycoproteins, which elicited a strong neutralizing antibody response in mice and showed potential in reducing viral loads, suggesting targeting OROV glycoproteins could be an effective vaccination strategy against OROV infection.

MBIO (2021)

添加到收藏夹

Review Microbiology

Current Status of Rabies and Its Eradication in Eastern and Southeastern Europe

Ivana Lojkic et al.

Summary: Most West and Central European countries are rabies-free, but the disease is still present in the eastern part of the EU. Oral vaccination is an effective method. Croatia has been rabies-free for seven years, but continuous efforts are needed to maintain this status.

PATHOGENS (2021)

添加到收藏夹

Article Microbiology

Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence

Ming Te Yeh et al.

CELL HOST & MICROBE (2020)

添加到收藏夹

Article Virology

A Genome-Wide CRISPR-Cas9 Screen Reveals the Requirement of Host Cell Sulfation for Schmallenberg Virus Infection

Thiprampai Thamamongood et al.

JOURNAL OF VIROLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism

Alexandra Serris et al.

CELL (2020)

添加到收藏夹

Article Biology

Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein

Ilona Rissanen et al.

ELIFE (2020)

添加到收藏夹

Article Immunology

Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France

Christophe Rodriguez et al.

EMERGING INFECTIOUS DISEASES (2020)

添加到收藏夹

Article Biology

Oropouche infection a neglected arbovirus in patients with acute febrile illness from the Peruvian coast

Johanna Martins-Luna et al.

BMC RESEARCH NOTES (2020)

添加到收藏夹

Article Immunology

Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy

Arthur W. D. Edridge et al.

CLINICAL INFECTIOUS DISEASES (2019)

添加到收藏夹

Article Virology

The CARD9-Associated C-Type Lectin, Mincle, Recognizes La Crosse Virus (LACV) but Plays a Limited Role in Early Antiviral Responses against LACV

Joao T. Monteiro et al.

VIRUSES-BASEL (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Orthobunyavirus spike architecture and recognition by neutralizing antibodies

Jan Hellert et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Biology

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

Eduardo A. Bignon et al.

ELIFE (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

High-Throughput Crystallization Pipeline at the Crystallography Core Facility of the Institut Pasteur

Patrick Weber et al.

MOLECULES (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Indirect ELISA based on Hendra and Nipah virus proteins for the detection of henipavirus specific antibodies in pigs

Kerstin Fischer et al.

PLOS ONE (2018)

添加到收藏夹

Article Microbiology

ESCRT machinery components are required for Orthobunyavirus particle production in Golgi compartments

Natalia S. Barbosa et al.

PLOS PATHOGENS (2018)

添加到收藏夹

Article Virology

Heparan Sulfate Proteoglycan Is an Important Attachment Factor for Cell Entry of Akabane and Schmallenberg Viruses

Shin Murakami et al.

JOURNAL OF VIROLOGY (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Structural basis for antibody-mediated neutralization of Lassa virus

Kathryn M. Hastie et al.

SCIENCE (2017)

添加到收藏夹

Article Multidisciplinary Sciences

A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion

P. Guardado-Calvo et al.

SCIENCE (2017)

添加到收藏夹

Article Virology

The Potential for Reassortment between Oropouche and Schmallenberg Orthobunyaviruses

Natasha L. Tilston-Lunel et al.

VIRUSES-BASEL (2017)

添加到收藏夹

Article Clinical Neurology

A Novel Cause of Chronic Viral Meningoencephalitis: Cache Valley Virus

Michael R. Wilson et al.

ANNALS OF NEUROLOGY (2017)

添加到收藏夹

Article Virology

Generation of Recombinant Oropouche Viruses Lacking the Nonstructural Protein NSm or NSs

Natasha L. Tilston-Lunel et al.

JOURNAL OF VIROLOGY (2016)

添加到收藏夹

Article Public, Environmental & Occupational Health

Isolation of Madre de Dios Virus (Orthobunyavirus; Bunyaviridae), an Oropouche Virus Species Reassortant, from a Monkey in Venezuela

Juan-Carlos Navarro et al.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2016)

添加到收藏夹

Review Microbiology

Reassortment in segmented RNA viruses: mechanisms and outcomes

Sarah M. McDonald et al.

NATURE REVIEWS MICROBIOLOGY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Bunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidase

Xiaohong Shi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion

Steinar Halldorsson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

添加到收藏夹

Article Microbiology

Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc

Pablo Guardado-Calvo et al.

PLOS PATHOGENS (2016)

添加到收藏夹

Article Microbiology

Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation

Shmuel Willensky et al.

PLOS PATHOGENS (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter

Piotr Gerlach et al.

CELL (2015)

添加到收藏夹

Review Microbiology

Orthobunyaviruses: recent genetic and structural insights

Richard M. Elliott

NATURE REVIEWS MICROBIOLOGY (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Deciphering key features in protein structures with the new ENDscript server

Xavier Robert et al.

NUCLEIC ACIDS RESEARCH (2014)

添加到收藏夹

Article Biochemical Research Methods

How good are my data and what is the resolution?

Philip R. Evans et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2013)

添加到收藏夹

Review Public, Environmental & Occupational Health

'Schmallenberg virus' - a novel orthobunyavirus emerging in Europe

M. Beer et al.

EPIDEMIOLOGY AND INFECTION (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Functional and evolutionary insight from the crystal structure of rubella virus protein E1

Rebecca M. DuBois et al.

NATURE (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization

Antonio Ariza et al.

NUCLEIC ACIDS RESEARCH (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein

Juan Reguera et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Crystal structure of glycoprotein C from Rift Valley fever virus

Moshe Dessau et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

添加到收藏夹

Review Virology

Viruses of the family Bunyaviridae: Are all available isolates reassortants?

Thomas Briese et al.

VIROLOGY (2013)

添加到收藏夹

Article Microbiology

Orthobunyavirus Ultrastructure and the Curious Tripodal Glycoprotein Spike

Thomas A. Bowden et al.

PLOS PATHOGENS (2013)

添加到收藏夹

Article Virology

Orthobunyavirus Entry into Neurons and Other Mammalian Cells Occurs via Clathrin-Mediated Endocytosis and Requires Trafficking into Early Endosomes

Bradley S. Hollidge et al.

JOURNAL OF VIROLOGY (2012)

添加到收藏夹

Article Biochemical Research Methods

NIH Image to ImageJ: 25 years of image analysis

Caroline A. Schneider et al.

NATURE METHODS (2012)

添加到收藏夹

Article Biochemistry & Molecular Biology

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

Fabian Sievers et al.

MOLECULAR SYSTEMS BIOLOGY (2011)

添加到收藏夹

Article Infectious Diseases

Iquitos Virus: A Novel Reassortant Orthobunyavirus Associated with Human Illness in Peru

Patricia V. Aguilar et al.

PLOS NEGLECTED TROPICAL DISEASES (2011)

添加到收藏夹

Article Biochemical Research Methods

Experimental phasing with SHELXC/D/E: combining chain tracing with density modification

George M. Sheldrick

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

添加到收藏夹

Article Biochemical Research Methods

XDS

Wolfgang Kabsch

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

添加到收藏夹

Article Biochemical Research Methods

Features and development of Coot

P. Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

添加到收藏夹

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

添加到收藏夹

Article Virology

Visualizing the Replication Cycle of Bunyamwera Orthobunyavirus Expressing Fluorescent Protein-Tagged Gc Glycoprotein

Xiaohong Shi et al.

JOURNAL OF VIROLOGY (2010)

添加到收藏夹

Article Virology

La Crosse virus (LACV) Gc fusion peptide mutants have impaired growth and fusion phenotypes, but remain neurotoxic

Samantha S. Soldan et al.

VIROLOGY (2010)

添加到收藏夹

Article Infectious Diseases

Arboviral Etiologies of Acute Febrile Illnesses in Western South America, 2000-2007

Brett M. Forshey et al.

PLOS NEGLECTED TROPICAL DISEASES (2010)

添加到收藏夹

Article Public, Environmental & Occupational Health

Etiology of Acute Undifferentiated Febrile Illness in the Amazon Basin of Ecuador

Stephen R. Manock et al.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2009)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein

Xiaohong Shi et al.

JOURNAL OF GENERAL VIROLOGY (2009)

添加到收藏夹

Article Virology

Role of the cytoplasmic tail domains of Bunyamwera orthobunyavirus glycoproteins Gn and Gc in virus assembly and morphogenesis

Xiaohong Shi et al.

JOURNAL OF VIROLOGY (2007)

添加到收藏夹

Article Virology

Mutagenesis of the La Crosse Virus glycoprotein supports a role for Gc (1066-1087) as the fusion peptide

Matthew L. Plassmeyer et al.

VIROLOGY (2007)

添加到收藏夹

Article Parasitology

Emergent arboviruses in Brazil

Luiz Tadeu Moraes Figueiredo

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL (2007)

添加到收藏夹

Article Virology

Batai and Ngari viruses: M segment reassortment and association with severe febrile disease outbreaks in East Africa

T Briese et al.

JOURNAL OF VIROLOGY (2006)

添加到收藏夹

Article Virology

Role of N-linked glycans on Bunyamwera virus glycoproteins in intracellular trafficking, protein folding, and virus infectivity

XH Shi et al.

JOURNAL OF VIROLOGY (2005)

添加到收藏夹

Article Virology

California serogroup, GC (Gl) glycoprotein is the principal determinant of pH-dependent cell fusion and entry

ML Plassmeyer et al.

VIROLOGY (2005)

添加到收藏夹

Article Virology

Ngari virus is a Bunyamwera virus reassortant that can be associated with large outbreaks of hemorrhagic fever in Africa

SR Gerrard et al.

JOURNAL OF VIROLOGY (2004)

添加到收藏夹

Article Veterinary Sciences

Efficacy of oral vaccination in the final stage of fox rabies elimination in Switzerland

P Bugnon et al.

JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH (2004)

添加到收藏夹

Article Biochemistry & Molecular Biology

Scoring function for automated assessment of protein structure template quality

Y Zhang et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)

添加到收藏夹

Article Biochemistry & Molecular Biology

WebLogo: A sequence logo generator

GE Crooks et al.

GENOME RESEARCH (2004)

添加到收藏夹

Article Biochemical Research Methods

Rapid selection of Drosophila S2 cells with the puromycin resistance gene

T Iwaki et al.

BIOTECHNIQUES (2003)

添加到收藏夹

Article Virology

A reassortant Bunyavirus isolated from acute hemorrhagic fever cases in Kenya and Somalia

MD Bowen et al.

VIROLOGY (2001)

添加到收藏夹

Article Biochemistry & Molecular Biology

The fusion glycoprotein shell of Semliki Forest virus: An icosahedral assembly primed for fusogenic activation at endosomal pH

J Lescar et al.

CELL (2001)

添加到收藏夹

Article Medicine, General & Internal

La crosse encephalitis in children.

JE McJunkin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.