4.7 Review

Antioxidants and Sports Performance

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Article Sport Sciences

The effect of high-intensity interval training and CoQ10 administration on hepatic CEACAM1 and PDGFA proteins in diet-induced obese rats

Sonia Ghiasi et al.

Summary: This study investigated the effects of high-intensity interval training (HIIT) and Coenzyme Q10 (CoQ10) supplementation on hepatic CEACAM1 and PDGFA proteins in obese male rats. The results showed that HIIT alleviated obesity-induced reduction of CEACAM1 and elevation of PDGFA, while CoQ10 supplementation and its combination with HIIT had no significant effect on CEACAM1 and PDGFA.

SPORT SCIENCES FOR HEALTH (2023)

Article Food Science & Technology

Interplay of dietary antioxidants and gut microbiome in human health: What has been learnt thus far?

Nikunj Naliyadhara et al.

Summary: The human gastrointestinal tract contains a diverse range of microbial species, which play a role in regulating gut barrier homeostasis, immune system stimulation, and neurological health benefits through the gut-brain axis. Dietary changes can significantly affect the gut microbial population, and positive changes can be made by changing dietary style. Dietary antioxidants, such as those found in food, have been found to have a positive impact on gut microbial populations, which can help alleviate gut microbial dysbiosis and contribute to the development of gut microbe-targeting therapeutics for various diseases. This review discusses the health benefits of major dietary antioxidant groups, and the interaction between gut microbiota and these antioxidants through pre-clinical and human dietary interventions.

JOURNAL OF FUNCTIONAL FOODS (2023)

Article Nutrition & Dietetics

Effects of High-Intensity Anaerobic Exercise on the Scavenging Activity of Various Reactive Oxygen Species and Free Radicals in Athletes

Yuri Sawada et al.

Summary: High-intensity exercise leads to an excess production of reactive oxygen species (ROS) in skeletal muscle, so athletes need to maintain higher ROS scavenging activity. We studied the changes in six different ROS scavenging activities in athletes after high-intensity anaerobic exercise. The results showed that some ROS scavenging activities increased immediately following the exercise, and the responsiveness of OH scavenging activity might be related to anaerobic exercise performance.

NUTRIENTS (2023)

Review Oncology

Metabolic Health, Mitochondrial Fitness, Physical Activity, and Cancer

Vicente Javier Clemente-Suarez et al.

Summary: Recent research suggests a strong link between the functioning of mitochondria and the development of cancer. Healthy mitochondria play a vital role in maintaining metabolic processes and controlling cell death, but inflammation can harm their function and lead to tissue damage. Engaging in both endurance and resistance exercises, in addition to maintaining an active lifestyle, can help improve mitochondrial functioning and reduce the risk of cancer.

CANCERS (2023)

Article Nutrition & Dietetics

12-week curcumin supplementation may relieve postexercise muscle fatigue in adolescent athletes

Kai-Yuan Bai et al.

Summary: This study evaluated the effect of curcumin on athletes' postexercise recovery. The results showed that curcumin can reduce muscle fatigue and soreness, indicating its potential to alleviate postexercise damage.

FRONTIERS IN NUTRITION (2023)

Review Nutrition & Dietetics

The Effect of Nitrate-Rich Beetroot Juice on Markers of Exercise-Induced Muscle Damage: A Systematic Review and Meta-Analysis of Human Intervention Trials

Louise Jones et al.

Summary: This systematic review and meta-analysis found that dietary nitrate supplementation, specifically in the form of beetroot juice, may help attenuate some markers of exercise-induced muscle damage. However, more large-scale controlled trials involving elite athletes are needed to further validate these findings.

JOURNAL OF DIETARY SUPPLEMENTS (2022)

Article Fisheries

Effect of Different Dietary Selenium Sources on Growth Performance, Antioxidant Capacity, Gut Microbiota, and Molecular Responses in Pacific White Shrimp Litopenaeus vannamei

Qiuran Yu et al.

Summary: This study investigated the effects of different dietary selenium sources on the growth performance, antioxidant capacity, gut microbiota, and molecular responses of Litopenaeus vannamei. The results showed that organic selenium, especially selenomethionine, is an effective feed supplement for promoting growth and antioxidant capacity, maintaining gut microbiota health, and promoting the utilization of fatty acid and glutathione peroxidase genes in shrimp fed a diet with 0.4 mg Se/kg.

AQUACULTURE NUTRITION (2022)

Review Environmental Sciences

Effect of Antioxidant Supplementation on Markers of Oxidative Stress and Muscle Damage after Strength Exercise: A Systematic Review

Cristina Canals-Garzon et al.

Summary: This systematic review found that consuming antioxidants in proper doses can have protective effects on oxidative stress and muscle damage after muscle strength exercise.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Review Biochemistry & Molecular Biology

Circadian Clocks, Redox Homeostasis, and Exercise: Time to Connect the Dots?

Conor McClean et al.

Summary: This review discusses the relationship between circadian rhythms, oxidative stress, and exercise stimuli. Research has found that disruptions to circadian rhythms can affect redox biology, and exercise has the potential to adjust these disruptions. However, exercise-induced oxidative stress can have both beneficial and harmful effects on health, depending on the type, intensity, and duration of exercise. Further research is needed to understand the optimal timing for exercise and physiological benefits in relation to the interactions between circadian rhythms, oxidative stress, and exercise.

ANTIOXIDANTS (2022)

Review Biochemistry & Molecular Biology

Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases

May Nasser Bin-Jumah et al.

Summary: Lycopene, a bioactive red pigment found in plants, has been shown to have positive effects on human health, including preventing chronic diseases such as diabetes and cardiovascular diseases. It acts as an antioxidant, lowers blood pressure, and improves lipid levels, thus protecting against coronary artery disease and hypertension.

ANTIOXIDANTS (2022)

Article Biochemistry & Molecular Biology

0-carotene improves fecal dysbiosis and intestinal dysfunctions in a mouse model of vitamin A deficiency

Maryam Honarbakhsh et al.

Summary: Vitamin A deficiency leads to intestinal inflammation, compromised barrier function, and dysbiosis of the gut microbiome. Supplementing with β-carotene can improve these issues, especially in cases of severe vitamin A deficiency. Additionally, β-carotene can also influence the composition of the gut microbiome.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2022)

Article Food Science & Technology

Exploring the potential of antioxidants from fruits and vegetables and strategies for their recovery

Ana Arias et al.

Summary: A balanced and nutritious diet, including 5 servings of fruits and vegetables a day, is crucial for maintaining good health. Fruits and vegetables are rich in antioxidants, which can improve immune system function and prevent various diseases. This review examines the antioxidant compounds in the most widely produced fruits and vegetables in Spain and explores green technologies for extracting antioxidants from waste fractions.

INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2022)

Review Nutrition & Dietetics

Vitamin Supplementation Protects against Nanomaterial-Induced Oxidative Stress and Inflammation Damages: A Meta-Analysis of In Vitro and In Vivo Studies

Dongli Xie et al.

Summary: Supplementation of vitamin E can effectively reduce oxidative stress and inflammatory responses induced by nanomaterials, providing a cost-effective option for prevention.

NUTRIENTS (2022)

Review Nutrition & Dietetics

Coenzyme Q10 Supplementation and Its Impact on Exercise and Sport Performance in Humans: A Recovery or a Performance-Enhancing Molecule?

Franchek Drobnic et al.

Summary: Evidence suggests that ROS can cause muscular injury and decrease physical performance. Therefore, supplementation with antioxidants is important for physically active individuals to recover from fatigue and prevent exercise damage. Coenzyme Q(10) has shown potential as a supplement for optimizing exercise performance and protecting muscles during exercise.

NUTRIENTS (2022)

Review Environmental Sciences

Nutritional and Exercise Interventions in Cancer-Related Cachexia: An Extensive Narrative Review

Vicente Javier Clemente-Suarez et al.

Summary: One common trait found in cancer patients is malnutrition and cachexia, which significantly impacts their health and quality of life. Comprehensive interventions that include nutrition, pharmacology, ergonutrition, and physical exercise strategies can improve patients' prognosis and quality of life. Cancer-related cachexia is a complex multifactorial phenomenon, with systemic inflammation playing a key role in its development and maintenance.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Article Biochemistry & Molecular Biology

Integrative analysis of multiomics data identifies selenium-related gene ALAD associating with keshan disease

Jichang Huang et al.

Summary: In this study, the selenium-related gene ALAD was identified as the causative gene for Keshan disease. ALAD was found to be essential for maintaining normal mitochondrial activity and cardiac function. These findings provide strong molecular evidence supporting the hypothesis of selenium deficiency in Keshan disease.

FREE RADICAL BIOLOGY AND MEDICINE (2022)

Article Fisheries

Effects of sodium selenite, selenium methionine, and selenium yeast on growth performance, carcass composition, blood biochemistry, and antioxidant status of intensively reared Hypophthalmichthys molitrix

Maida Mushtaq et al.

Summary: In the current study, the effects of different selenium sources on silver carp were evaluated. The results showed that dietary supplementation with 0.5 mg/kg of selenium methionine improved the growth performance, organ enrichment, and antioxidant status of the fish.

AQUACULTURE REPORTS (2022)

Review Biology

The Relationship between Physical Activity, Physical Exercise, and Human Gut Microbiota in Healthy and Unhealthy Subjects: A Systematic Review

Stefania Cataldi et al.

Summary: This systematic review explores the relationship between physical activity/exercise and the human gut microbiota. It finds that aerobic exercise is associated with increased diversity in the gut microbiota, while resistance training does not show a significant correlation. Training duration may be related to the abundance of the Prevotella genus. Exercising according to the minimum dose recommended by the World Health Organizations does not have a significant impact on gut microbiota richness and diversity. Intense and prolonged physical exercise may lead to higher abundance of pro-inflammatory bacteria. Physical activity does not lead to significant changes in gut microbiota diversity in elderly individuals. The heterogeneity of training parameters, diet control, and sequencing methods are confounding factors in the studies.

BIOLOGY-BASEL (2022)

Review Green & Sustainable Science & Technology

Physical Activity and Nutritional Pattern Related to Maturation and Development

Alvaro Bustamante-Sanchez et al.

Summary: In this study, the authors conducted a narrative review to analyze the patterns of physical activity and nutrition related to maturation and development in children. They found that physical activity and nutrition are fundamental for the correct development and maturation of children.

SUSTAINABILITY (2022)

Review Nutrition & Dietetics

Advances in the Study of the Mechanism by Which Selenium and Selenoproteins Boost Immunity to Prevent Food Allergies

Kongdi Zhu et al.

Summary: Selenium and selenoproteins play important roles in regulating the immune system, and have a certain effect in preventing food allergies.

NUTRIENTS (2022)

Article Biochemistry & Molecular Biology

Redox signaling regulates skeletal muscle remodeling in response to exercise and prolonged inactivity

Scott K. Powers et al.

Summary: This review examines the role of redox signaling in skeletal muscle adaptation during both exercise and prolonged muscle inactivity. Muscle exercise leads to acute increase in reactive oxygen species (ROS) production in contracting fibers, while prolonged muscle disuse results in chronic elevation in ROS production in inactive fibers. These different patterns of ROS production stimulate divergent cell signaling pathways to promote muscle remodeling.

REDOX BIOLOGY (2022)

Article Sport Sciences

Potential harms of supplementation with high doses of antioxidants in athletes

Shunchang Li et al.

Summary: Vigorous exercise leads to the production of reactive oxygen species (ROS), causing some athletes to consume antioxidants in order to counteract oxidative stress. However, there is currently insufficient evidence to support the benefits of antioxidant supplementation during exercise. On the contrary, high doses of antioxidants can hinder the physiological functions that promote training adaptation and health.

JOURNAL OF EXERCISE SCIENCE & FITNESS (2022)

Review Biochemistry & Molecular Biology

Selenium: An Antioxidant with a Critical Role in Anti-Aging

Geir Bjorklund et al.

Summary: Selenium plays an important role in improving antioxidant defense, immune functions, and metabolic homeostasis. Inadequate selenium status can accelerate the aging process and increase the risk of diseases. This review introduces the role of selenium in aging mechanisms and its potential clinical implications.

MOLECULES (2022)

Review Biochemistry & Molecular Biology

Grape Polyphenols in the Treatment of Human Skeletal Muscle Damage Due to Inflammation and Oxidative Stress during Obesity and Aging: Early Outcomes and Promises

Adriana Capozzi et al.

Summary: Inactivity and high-calorie diets contribute to obesity and premature aging, while improvements in healthcare management have led to a growing population of elderly people. Obesity and aging are major risk factors for non-communicable diseases that result in comorbidities and increased mortality, particularly affecting skeletal muscle mass and quality. Skeletal muscles are important for various bodily functions and limiting their deterioration is a significant public health and socio-economic challenge. Supplementation with natural compounds like grape polyphenols has shown potential in regulating metabolic pathways and preventing obesity and aging-related muscle comorbidities in cell and animal studies. However, there is a lack of clinical studies validating these promising results observed in animal models.

MOLECULES (2022)

Article Geriatrics & Gerontology

Resveratrol and exercise combined to treat functional limitations in late life: A pilot randomized controlled trial

Sara A. Harper et al.

Summary: The study aimed to evaluate the safety and feasibility of combining exercise and resveratrol to treat older adults, showing that this combined treatment may improve skeletal muscle mitochondrial function and mobility-related indices of physical function. A larger trial is warranted to further validate these findings.

EXPERIMENTAL GERONTOLOGY (2021)

Review Nutrition & Dietetics

Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases

Rannapaula Lawrynhuk Urbano Ferreira et al.

Summary: Selenium plays a crucial role in various bodily functions and maintaining a healthy gut microbiota. Its symbiotic relationship with gut bacteria helps in improving the bioavailability of selenocompounds and balancing microbial flora to prevent health damage associated with dysbiosis. However, selenium deficiency can lead to a phenotype of gut microbiota that is more susceptible to certain diseases, highlighting the importance of adequate selenium intake for both human and bacterial health.

FRONTIERS IN NUTRITION (2021)

Review Nutrition & Dietetics

Grape polyphenols supplementation for exercise-induced oxidative stress

Edurne Elejalde et al.

Summary: Exercise increases the production of free radicals, leading to elevated oxidative stress, which can have detrimental effects at high concentrations. Supplementing with antioxidants can help maintain optimal antioxidant status, and grapes are a natural source of antioxidants that can potentially reduce exercise-induced oxidative stress in athletes.

JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2021)

Review Biochemistry & Molecular Biology

Gut Microbiota as a Mediator of Essential and Toxic Effects of Zinc in the Intestines and Other Tissues

Anatoly V. Skalny et al.

Summary: The present study reviewed the association between Zn status and gut microbiota characteristics, as well as the potential role of Zn-induced microbiota in modulating systemic effects. The data showed a close relationship between Zn metabolism and gut microbiota, with Zn being a significant factor for gut bacteria biodiversity. Physiological and nutritional Zn doses improved gut wall integrity, while Zn overexposure induced substantial alterations in gut microbiota.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Endocrinology & Metabolism

Nox4 mediates skeletal muscle metabolic responses to exercise

Kalyn S. Specht et al.

Summary: The study reveals the crucial role of Nox4 in exercise-induced skeletal muscle metabolism, influencing glucose and fatty acid oxidation through promoting immediate responses. Global Nox4 deletion resulted in decreased glucose and fatty acid oxidation post-exercise, potentially through regulation of UCP3 expression. Endothelial-Nox4 is similarly crucial for glucose and fatty acid oxidation, suggesting inter-tissue cross-talk between endothelium and skeletal muscle in response to exercise.

MOLECULAR METABOLISM (2021)

Article Biochemistry & Molecular Biology

β-carotene oxygenase 2 deficiency-triggered mitochondrial oxidative stress promotes low-grade inflammation and metabolic dysfunction

Lei Wu et al.

Summary: BCO2 plays a crucial role in mitochondrial respiration and metabolic homeostasis in mammals. Its deficiency or decreased expression leads to mitochondrial oxidative stress, low-grade inflammation, and the subsequent development of metabolic disorders.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Article Chemistry, Medicinal

Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes

Sze Wa Chan et al.

Summary: Short-term bilberry supplementation in patients with type 2 diabetes did not have significant effects on glycemic control, lipid profile, antioxidant status, or inflammatory status. However, the trend towards improved glycemic control may suggest that longer treatment periods could be effective in diabetic patients.

PHYTOTHERAPY RESEARCH (2021)

Review Biotechnology & Applied Microbiology

Effect of Different Exercise Modalities on Oxidative Stress: A Systematic Review

Anand Thirupathi et al.

Summary: Exercise-induced benefits in promoting health and preventing diseases are increasingly recognized, but different types and intensities of exercise may increase oxidative damage. The training status of the individual and specific oxidative damage markers play a crucial role in predicting oxidative damage. More follow-up programs with larger numbers are needed to confirm findings.

BIOMED RESEARCH INTERNATIONAL (2021)

Article Nutrition & Dietetics

L-Carnitine Tartrate Supplementation for 5 Weeks Improves Exercise Recovery in Men and Women: A Randomized, Double-Blind, Placebo-Controlled Trial

Matthew Stefan et al.

Summary: The study indicates that L-carnitine tartrate supplementation can improve short-term recovery among athletes, while longer-term effects in the general population need further research. The experiment found that L-carnitine tartrate supplementation for 5 weeks could enhance perceived recovery and reduce soreness, as well as lower serum creatine kinase levels.

NUTRIENTS (2021)

Review Biochemistry & Molecular Biology

Supplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review

Maria F. Torre et al.

Summary: There is insufficient evidence to confirm that antioxidant vitamins intake can minimize delayed-onset muscle soreness after eccentric exercise. Although some studies show the beneficial effects of chronic supplementation with vitamins C and E on muscle soreness, further research is needed to confirm their effectiveness in this context.

ANTIOXIDANTS (2021)

Article Nutrition & Dietetics

The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

Stine D. Sondergard et al.

Summary: Oral glutathione (GSH) supplementation improves insulin sensitivity in obese subjects, but does not alter markers of oxidative stress.

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2021)

Review Pharmacology & Pharmacy

Zinc supplementation as an adjunct therapy for COVID-19: Challenges and opportunities

Vidyasagar Chinni et al.

Summary: This article discusses zinc as a potential therapeutic option to reduce the severity of COVID-19 infection, emphasizing the possible therapeutic effect of zinc therapy. However, realizing the therapeutic value of zinc still faces challenges due to the lack of optimal treatment modalities.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2021)

Review Food Science & Technology

Food flavonols: Nutraceuticals with complex health benefits and functionalities

Davide Barreca et al.

Summary: Flavonols are bioactive compounds with health-promoting properties, including antioxidation, cardioprotection, antibacterial, antiviral, and anticancer activities. Incorporating flavonols into the human diet is highly recommended for their impressive health benefits, making them excellent nutraceuticals and ingredients for functional food. The metabolization process of flavonols also produces compounds with significant bioactivities, similar to their precursors.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

Review Biochemistry & Molecular Biology

Exercise-Stimulated ROS Sensitive Signaling Pathways in Skeletal Muscle

Jessica Bouviere et al.

Summary: Physical exercise induces acute and adaptative responses at the cellular and systemic levels through the modulation of various signaling pathways in skeletal muscle. Antioxidants can blunt these adaptations, highlighting the crucial role of ROS in exercise. Understanding the balance between beneficial and harmful effects of ROS during and after exercise is a challenging question in exercise biology.

ANTIOXIDANTS (2021)

Review Nutrition & Dietetics

Vitamin A and Vitamin E: Will the Real Antioxidant Please Stand Up?

William S. Blaner et al.

Summary: This review focuses on the mechanisms of action of vitamin A and vitamin E in the body, suggesting that vitamin A acts as an indirect antioxidant by transcriptionally regulating genes involved in antioxidant responses, while vitamin E functions as a direct antioxidant and helps prevent the increase of peroxidized lipids that affect metabolic pathways and gene expression profiles. The review also discusses the lack of compelling evidence for a direct transcriptional mechanism of vitamin E similar to that of vitamin A.

ANNUAL REVIEW OF NUTRITION, VOL 41, 2021 (2021)

Article Dentistry, Oral Surgery & Medicine

Inhibition of Streptococcus mutans, antioxidant property and cytotoxicity of novel nano-zinc oxide varnish

Manali Deb Barma et al.

Summary: The study demonstrated that zinc oxide nanoparticles are effective in inhibiting S. mutans growth and biofilm formation, while also showing promising antioxidant potential and low cytotoxicity on human cell lines. These findings suggest that ZnO-NP varnish has great potential as an effective anticaries agent.

ARCHIVES OF ORAL BIOLOGY (2021)

Review Nutrition & Dietetics

Nutrition in the Actual COVID-19 Pandemic. A Narrative Review

Vicente Javier Clemente-Suarez et al.

Summary: The study found that the COVID-19 lockdown led to unhealthy dietary changes and weight gain, with obesity and low physical activity levels increasing the risk of COVID-19 infection and pathological processes. Hospitalized COVID-19 patients were also found to experience malnutrition and deficiencies in various vitamins. Further research is needed to fully understand the role of nutrition in both preventing and treating COVID-19 patients.

NUTRIENTS (2021)

Article Microbiology

Organic Selenium Increased Gilts Antioxidant Capacity, Immune Function, and Changed Intestinal Microbiota

Zimei Li et al.

Summary: This study found that HMSeBA can increase tissue selenium content and selenoprotein P concentration in gilts, improve antioxidant enzyme activity, regulate immune function, and alter the structure of intestinal microbiota.

FRONTIERS IN MICROBIOLOGY (2021)

Article Biochemistry & Molecular Biology

Vitamin C Supplementation in Healthy Individuals Leads to Shifts of Bacterial Populations in the Gut-A Pilot Study

Antonius T. Otten et al.

Summary: High-dose vitamin C supplementation can modulate the composition of gut microbiota in healthy individuals, leading to beneficial shifts in bacterial populations.

ANTIOXIDANTS (2021)

Article Food Science & Technology

Anti-Hyperlipidemia and Gut Microbiota Community Regulation Effects of Selenium-Rich Cordyceps militaris Polysaccharides on the High-Fat Diet-Fed Mice Model

Minglei Yu et al.

Summary: Supplementation of Se-rich C. militaris polysaccharides showed anti-obesity effects by reducing serum triglyceride and LDL-C levels, inhibiting inflammation, promoting satiety and thermogenesis in HFD-fed mice. It also modulated gut microbiota by decreasing harmful bacteria and increasing beneficial bacteria, which could potentially be used as functional foods against obesity and dysbiosis.
Article Medicine, General & Internal

Oral Resveratrol supplementation attenuates exercise-induced Interleukin-6 but not Oxidative Stress after a high intensity cycling challenge in adults

Jung-Piao Tsao et al.

Summary: Previous studies have shown that RES supplementation does not significantly enhance high-intensity cycling exercise performance and oxidative stress, but can decrease IL-6 response during exercise.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2021)

Review Biophysics

High-altitude hypoxia induced reactive oxygen species generation, signaling, and mitigation approaches

Priya Gaur et al.

Summary: The balance between oxidants and antioxidants is essential for aerobic life, but can be disrupted at high altitudes, leading to oxidative stress. Exposure to high altitude causes increased ROS production, which can lead to various pathophysiological conditions. Antioxidants play a crucial role in protecting cells from oxidative damage and reducing the risk of altitude-related illnesses.

INTERNATIONAL JOURNAL OF BIOMETEOROLOGY (2021)

Review Sport Sciences

Antioxidants for preventing and reducing muscle soreness after exercise: a Cochrane systematic review

Mayur K. Ranchordas et al.

BRITISH JOURNAL OF SPORTS MEDICINE (2020)

Article Food Science & Technology

Vitamin E (α-tocopherol) consumption influences gut microbiota composition

Yukyung Choi et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2020)

Review Biochemistry & Molecular Biology

Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights

Shaun A. Mason et al.

REDOX BIOLOGY (2020)

Review Hospitality, Leisure, Sport & Tourism

Exercise-induced oxidative stress: Friend or foe?

Scott K. Powers et al.

JOURNAL OF SPORT AND HEALTH SCIENCE (2020)

Review Biochemistry & Molecular Biology

Redox basis of exercise physiology

N. V. Margaritelis et al.

REDOX BIOLOGY (2020)

Article Nutrition & Dietetics

Avenanthramide supplementation reduces eccentric exercise-induced inflammation in young men and women

Tianou Zhang et al.

JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2020)

Review Nutrition & Dietetics

Migraine and Diet

Parisa Gazerani

NUTRIENTS (2020)

Review Biochemistry & Molecular Biology

Advances on Food-Derived Peptidic Antioxidants-A Review

Mingfei Pan et al.

ANTIOXIDANTS (2020)

Review Environmental Sciences

Antioxidants and Exercise Performance: With a Focus on Vitamin E and C Supplementation

Madalyn Riley Higgins et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

Review Biochemistry & Molecular Biology

Targeted Antioxidants in Exercise-Induced Mitochondrial Oxidative Stress: Emphasis on DNA Damage

Josh Williamson et al.

ANTIOXIDANTS (2020)

Review Biochemistry & Molecular Biology

Mediators of Physical Activity Protection against ROS-Linked Skeletal Muscle Damage

Sergio Di Meo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biochemistry & Molecular Biology

Adaptations to high-intensity interval training in skeletal muscle require NADPH oxidase 2

Carlos Henriquez-Olguin et al.

REDOX BIOLOGY (2019)

Review Nutrition & Dietetics

Omega-3 Polyunsaturated Fatty Acids: Benefits and Endpoints in Sport

Maria Alessandra Gammone et al.

NUTRIENTS (2019)

Review Cell Biology

Pro- and Antioxidant Effects of Vitamin C in Cancer in correspondence to Its Dietary and Pharmacological Concentrations

Elzbieta Pawlowska et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

Review Endocrinology & Metabolism

Microbial regulation of organismal energy homeostasis

Patrice D. Cani et al.

NATURE METABOLISM (2019)

Review Biochemistry & Molecular Biology

Molecular Mechanisms of Zinc as a Pro-Antioxidant Mediator: Clinical Therapeutic Implications

Ananda S. Prasad et al.

ANTIOXIDANTS (2019)

Review Cell Biology

The Science and Translation of Lactate Shuttle Theory

George A. Brooks

CELL METABOLISM (2018)

Review Physiology

Reactive Oxygen Species and Pulmonary Vasculature During Hypobaric Hypoxia

Patricia Siques et al.

FRONTIERS IN PHYSIOLOGY (2018)

Article Biochemistry & Molecular Biology

The effect of 6-week zinc supplement and weight training on the blood lipids of the sedentaries and athletes

Vedat Cinar et al.

CELLULAR AND MOLECULAR BIOLOGY (2018)

Review Sport Sciences

The Antioxidant Effect of Exercise: A Systematic Review and Meta-Analysis

Caio Victor de Sousa et al.

SPORTS MEDICINE (2017)

Article Sport Sciences

Effect of Melatonin Supplementation on Antioxidant Status and DNA Damage in High Intensity Trained Athletes

Manuel Ortiz-Franco et al.

INTERNATIONAL JOURNAL OF SPORTS MEDICINE (2017)

Article Nutrition & Dietetics

The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance-trained athletes

Roberto C. Leonardo-Mendonca et al.

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2017)

Review Biochemistry & Molecular Biology

Biological Activity of Selenium: Revisited

Jagoda K. Wrobel et al.

IUBMB LIFE (2016)

Review Neurosciences

Redox interventions to increase exercise performance

Michael B. Reid

JOURNAL OF PHYSIOLOGY-LONDON (2016)

Article Biochemistry & Molecular Biology

Oxidative stress and antioxidants: Distress or eustress?

Etsuo Niki

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2016)

Article Biochemistry & Molecular Biology

Physical exercise, reactive oxygen species and neuroprotection

Zsolt Radak et al.

FREE RADICAL BIOLOGY AND MEDICINE (2016)

Article Nutrition & Dietetics

Vitamin E supplementation inhibits muscle damage and inflammation after moderate exercise in hypoxia

S. A. Santos et al.

JOURNAL OF HUMAN NUTRITION AND DIETETICS (2016)

Review Neurosciences

Do antioxidant supplements interfere with skeletal muscle adaptation to exercise training?

Troy L. Merry et al.

JOURNAL OF PHYSIOLOGY-LONDON (2016)

Review Physiology

Redox Mechanism of Reactive Oxygen Species in Exercise

Feng He et al.

FRONTIERS IN PHYSIOLOGY (2016)

Article Rehabilitation

Impact of aerobic and anaerobic exercise training on oxidative stress and antioxidant defense in athletes

Song-Young Park et al.

JOURNAL OF EXERCISE REHABILITATION (2016)

Review Cell Biology

Resveratrol supplementation: Where are we now and where should we go?

Marta G. Novelle et al.

AGEING RESEARCH REVIEWS (2015)

Article Physiology

Attenuation of indirect markers of eccentric exercise-induced muscle damage by curcumin

Yoko Tanabe et al.

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2015)

Article Physiology

Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS)

Lesley M. Nicol et al.

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2015)

Review Chemistry, Medicinal

The role of antioxidants in the chemistry of oxidative stress: A review

Aurelia Magdalena Pisoschi et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Sport Sciences

Does Combined Antioxidant Vitamin Supplementation Blunt Repeated Bout Effect?

F. He et al.

INTERNATIONAL JOURNAL OF SPORTS MEDICINE (2015)

Review Nutrition & Dietetics

Exercise and oxidative stress: Potential effects of antioxidant dietary strategies in sports

Alessandro Pingitore et al.

NUTRITION (2015)

Review Sport Sciences

Impact of Dietary Antioxidants on Sport Performance: A Review

Andrea J. Braakhuis et al.

SPORTS MEDICINE (2015)

Review Biochemistry & Molecular Biology

Oxidative stress: a concept in redox biology and medicine

Helmut Sies

REDOX BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Impact of Oxidative Stress on Exercising Skeletal Muscle

Peter Steinbacher et al.

BIOMOLECULES (2015)

Article Sport Sciences

Effects of dietary antioxidants on training and performance in female runners

Andrea J. Braakhuis et al.

EUROPEAN JOURNAL OF SPORT SCIENCE (2014)

Review Biochemistry & Molecular Biology

Free radicals and sprint exercise in humans

D. Morales-Alamo et al.

FREE RADICAL RESEARCH (2014)

Review Biochemistry & Molecular Biology

Role of exercise-induced reactive oxygen species in the modulation of heat shock protein response

S. Fittipaldi et al.

FREE RADICAL RESEARCH (2014)

Article Nutrition & Dietetics

Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial

Franchek Drobnic et al.

JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2014)

Article Sport Sciences

Vitamin Supplementation Benefits in Master Athletes

Jeanick Brisswalter et al.

SPORTS MEDICINE (2014)

Review Nutrition & Dietetics

Potential Role of Carotenoids as Antioxidants in Human Health and Disease

Joanna Fiedor et al.

NUTRIENTS (2014)

Article Physiology

Dietary nitrate supplementation improves team sport-specific intense intermittent exercise performance

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EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2013)

Review Biochemistry & Molecular Biology

Exploring the Role of Genetic Variability and Lifestyle in Oxidative Stress Response for Healthy Aging and Longevity

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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Nutrition & Dietetics

Blood Oxidative-Stress Markers During a High-Altitude Trek

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INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM (2013)

Article Nutrition & Dietetics

Effects of a Flavonoid-Rich Juice on Inflammation, Oxidative Stress, and Immunity in Elite Swimmers: A Metabolomics-Based Approach

Amy M. Knab et al.

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM (2013)

Review Nutrition & Dietetics

The Effect of Nitrate Supplementation on Exercise Performance in Healthy Individuals: A Systematic Review and Meta-Analysis

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INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM (2013)

Article Physiology

Beetroot juice and exercise: pharmacodynamic and dose-response relationships

Lee J. Wylie et al.

JOURNAL OF APPLIED PHYSIOLOGY (2013)

Article Neurosciences

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

Lasse Gliemann et al.

JOURNAL OF PHYSIOLOGY-LONDON (2013)

Review Cell Biology

Nutrition and Healthy Ageing: Calorie Restriction or Polyphenol-Rich MediterrAsian Diet?

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OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Article Biochemistry & Molecular Biology

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

Jorge L. Ruas et al.

Article Biochemistry & Molecular Biology

Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium

Vasanthi R. Muthusamy et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Review Biotechnology & Applied Microbiology

Reactive Oxygen Species in Health and Disease

Assim A. Alfadda et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)

Article Nutrition & Dietetics

Coenzyme Q10 supplementation and exercise-induced oxidative stress in humans

Bengt Ostman et al.

NUTRITION (2012)

Article Medicine, General & Internal

Effect of Supplementation With High-Selenium Yeast on Plasma Lipids A Randomized Trial

Margaret P. Rayman et al.

ANNALS OF INTERNAL MEDICINE (2011)

Review Biochemistry & Molecular Biology

Exercise-induced oxidative stress in humans: Cause and consequences

Scott K. Powers et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Article Neurosciences

Reactive oxygen and nitrogen species as intracellular signals in skeletal muscle

Scott K. Powers et al.

JOURNAL OF PHYSIOLOGY-LONDON (2011)

Article Sport Sciences

Antioxidant Supplementation Reduces Skeletal Muscle Mitochondrial Biogenesis

Natalie A. Strobel et al.

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2011)

Article Sport Sciences

Acute Dietary Nitrate Supplementation Improves Cycling Time Trial Performance

Katherine E. Lansley et al.

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2011)

Review Sport Sciences

Antioxidant Supplementation during Exercise Training Beneficial or Detrimental?

Tina-Tinkara Peternelj et al.

SPORTS MEDICINE (2011)

Article Physiology

Reactive Oxygen Species: Impact on Skeletal Muscle

Scott K. Powers et al.

COMPREHENSIVE PHYSIOLOGY (2011)

Article Biochemistry & Molecular Biology

Effect of Zinc Supplementation on Antioxidant Activity in Young Wrestlers

Ersan Kara et al.

BIOLOGICAL TRACE ELEMENT RESEARCH (2010)

Article Nutrition & Dietetics

Experimental Guidelines for Studies Designed to Investigate the Impact of Antioxidant Supplementation on Exercise Performance

Scott K. Powers et al.

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM (2010)

Article Sport Sciences

Effect of quercetin supplementation on maximal oxygen uptake in men and women

Matthew S. Ganio et al.

JOURNAL OF SPORTS SCIENCES (2010)

Article Sport Sciences

EFFECTS OF DIFFERENT RESISTANCE TRAINING INTENSITY ON INDICES OF OXIDATIVE STRESS

Hayriye Cakir-Atabek et al.

JOURNAL OF STRENGTH AND CONDITIONING RESEARCH (2010)

Article Sport Sciences

Antioxidant Supplementation Does Not Alter Endurance Training Adaptation

Christina Yfanti et al.

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2010)

Article Sport Sciences

Influence of tart cherry juice on indices of recovery following marathon running

G. Howatson et al.

SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS (2010)

Article Biochemistry & Molecular Biology

Exercise activation of muscle peroxisome proliferator-activated receptor-γ coactivator-1α signaling is redox sensitive

Chounghun Kang et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Sport Sciences

Changes of ROS during a Two-day Ultra-marathon Race

N. Hattori et al.

INTERNATIONAL JOURNAL OF SPORTS MEDICINE (2009)

Article Physiology

Dietary quercetin supplementation is not ergogenic in untrained men

Kirk J. Cureton et al.

JOURNAL OF APPLIED PHYSIOLOGY (2009)

Article Nutrition & Dietetics

Fruit and Vegetable Consumption and Its Relation to Markers of Inflammation and Oxidative Stress in Adolescents

Erica M. Holt et al.

JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION (2009)

Article Sport Sciences

Antioxidants Do Not Prevent Postexercise Peroxidation and May Delay Muscle Recovery

Vitor H. Teixeira et al.

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2009)

Article Multidisciplinary Sciences

Antioxidants prevent health-promoting effects of physical exercise in humans

Michael Ristow et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Sport Sciences

Does Antioxidant Vitamin Supplementation Protect against Muscle Damage?

Cian McGinley et al.

SPORTS MEDICINE (2009)

Article Pharmacology & Pharmacy

Chronic Inflammation and Oxidative Stress as a Major Cause of Age-Related Diseases and Cancer

Nemat Khansari et al.

RECENT PATENTS ON INFLAMMATION & ALLERGY DRUG DISCOVERY (2009)

Article Nutrition & Dietetics

Dietary patterns and C-reactive protein in Japanese men and women

Akiko Nanri et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)

Article Nutrition & Dietetics

Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance

Mari-Carmen Gomez-Cabrera et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)

Review Biochemistry & Molecular Biology

Redox regulation of cell survival

Dunyaporn Trachootham et al.

ANTIOXIDANTS & REDOX SIGNALING (2008)

Article Nutrition & Dietetics

Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10

Michihiro Kon et al.

BRITISH JOURNAL OF NUTRITION (2008)

Article Nutrition & Dietetics

Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals

Matthew Cooke et al.

JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2008)

Article Sport Sciences

Effects of strength and endurance training on antioxidant enzyme gene expression and activity in middle-aged men

D. Garcia-Lopez et al.

SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS (2007)

Article Multidisciplinary Sciences

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Sibylle Jaeger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Medicine, General & Internal

Effect of a traditional mediterranean diet on lipoprotein oxidation -: A randomized controlled trial

Montserrat Fito et al.

ARCHIVES OF INTERNAL MEDICINE (2007)

Article Sport Sciences

Antioxidant diet supplementation enhances aerobic performance in amateur sportsmen

Antoni Aguilo et al.

JOURNAL OF SPORTS SCIENCES (2007)

Review Clinical Neurology

Oxidative stress, chronic disease, and muscle wasting

Jennifer S. Moylan et al.

MUSCLE & NERVE (2007)

Review Physiology

The production of reactive oxygen and nitrogen species by skeletal muscle

Malcolm J. Jackson et al.

JOURNAL OF APPLIED PHYSIOLOGY (2007)

Review Pharmacology & Pharmacy

Carotenoids and human health

A. V. Rao et al.

PHARMACOLOGICAL RESEARCH (2007)

Article Nutrition & Dietetics

Dietary antioxidant supplementation combined with quercetin improves cycling time trial performance

Holden S-H. MacRae et al.

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM (2006)

Review Biology

Coordination of metabolic plasticity in skeletal muscle

David A. Hood et al.

JOURNAL OF EXPERIMENTAL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Antioxidant enzyme activity is up-regulated after unilateral resistance exercise training in older adults

G Parise et al.

FREE RADICAL BIOLOGY AND MEDICINE (2005)

Article Biochemistry & Molecular Biology

Skeletal muscles, heart, and lung are the main sources of oxygen radicals in old rats

AV Kozlov et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Review Biochemistry & Molecular Biology

Mitochondrial superoxide: Production, biological effects, and activation of uncoupling proteins

MD Brand et al.

FREE RADICAL BIOLOGY AND MEDICINE (2004)

Review Nutrition & Dietetics

Vitamin and mineral status: Effects on physical performance

HC Lukaski

NUTRITION (2004)

Article Biochemistry & Molecular Biology

Antioxidant supplementation prevents exercise-induced lipid peroxidation, but not inflammation, in ultramarathon runners

A Mastaloudis et al.

FREE RADICAL BIOLOGY AND MEDICINE (2004)

Review Pharmacology & Pharmacy

Oxidative stress, exercise, and antioxidant supplementation

ML Urso et al.

TOXICOLOGY (2003)

Article Physiology

Resistance exercise training attenuates exercise-induced lipid peroxidation in the elderly

KR Vincent et al.

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2002)

Article Sport Sciences

Contraction-induced muscle damage is unaffected by vitamin E supplementation

LJ Beaton et al.

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2002)

Article Biochemistry & Molecular Biology

Oxidative DNA damage in human peripheral leukocytes induced by massive aerobic exercise

K Tsai et al.

FREE RADICAL BIOLOGY AND MEDICINE (2001)

Article Sport Sciences

Vitamin E supplementation and endurance exercise - Are there benefits?

Y Takanami et al.

SPORTS MEDICINE (2000)