Global Impacts of Western Diet and Its Effects on Metabolism and Health: A Narrative Review

The Western diet is a modern dietary pattern characterized by high intakes of pre-packaged foods, refined grains, red meat, processed meat, high-sugar drinks, candy, sweets, fried foods, conventionally raised animal products, high-fat dairy products, and high-fructose products. The present review aims to describe the effect of the Western pattern diet on the metabolism, inflammation, and antioxidant status; the impact on gut microbiota and mitochondrial fitness; the effect of on cardiovascular health, mental health, and cancer; and the sanitary cost of the Western diet. To achieve this goal, a consensus critical review was conducted using primary sources, such as scientific articles, and secondary sources, including bibliographic indexes, databases, and web pages. Scopus, Embase, Science Direct, Sports Discuss, ResearchGate, and the Web of Science were used to complete the assignment. MeSH-compliant keywords such Western diet, inflammation, metabolic health, metabolic fitness, heart disease, cancer, oxidative stress, mental health, and metabolism were used. The following exclusion criteria were applied: (i) studies with inappropriate or irrelevant topics, not germane to the review's primary focus; (ii) Ph.D. dissertations, proceedings of conferences, and unpublished studies. This information will allow for a better comprehension of this nutritional behavior and its effect on an individual's metabolism and health, as well as the impact on national sanitary systems. Finally, practical applications derived from this information are made.

Automated summary

The Western diet, characterized by high consumption of pre-packaged foods, red meat, sugary drinks, and fried foods, has significant effects on metabolism, inflammation, antioxidant status, gut microbiota, mitochondrial fitness, cardiovascular health, mental health, and cancer. A critical review was conducted using primary and secondary sources to provide a comprehensive understanding of this dietary pattern's impact on individuals' health and national healthcare systems. Practical applications based on the findings were also suggested.