相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Non-alcoholic fatty liver disease
Elizabeth E. Powell et al.
LANCET (2021)
Lipotoxic Hepatocyte-Derived Exosomal MicroRNA 192-5p Activates Macrophages Through Rictor/Akt/Forkhead Box Transcription Factor O1 Signaling in Nonalcoholic Fatty Liver Disease
Xiao-Lin Liu et al.
HEPATOLOGY (2020)
Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease
Ze Chen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2020)
Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders
Judith Aron-Wisnewsky et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)
Dual Specificity Phosphatase 12 Regulates Hepatic Lipid Metabolism Through Inhibition of the Lipogenesis and Apoptosis Signal-Regulating Kinase 1 Pathways
Zhen Huang et al.
HEPATOLOGY (2019)
The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide
Yuxun Zhang et al.
REDOX BIOLOGY (2019)
Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD
Cyrielle Caussy et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2019)
Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial
Zobair M. Younossi et al.
LANCET (2019)
The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids
Puneet Puri et al.
HEPATOLOGY (2018)
Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism
Preeti Pathak et al.
HEPATOLOGY (2018)
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and-7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1 beta Activation
James E. Vince et al.
CELL REPORTS (2018)
Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease
Oscar Chavez-Talavera et al.
GASTROENTEROLOGY (2017)
New trends on obesity and NAFLD in Asia
Jian-Gao Fan et al.
JOURNAL OF HEPATOLOGY (2017)
Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK9, lipoprotein(a) and apolipoprotein C-III
M. Ghosh Laskar et al.
JOURNAL OF INTERNAL MEDICINE (2017)
Structure-Property Relationships in Sodium Muricholate Derivative (Bile Salts) Micellization: The Effect of Conformation of Steroid Skeleton on Hydrophobicity and Micelle Formation-Pattern Recognition and Potential Membranoprotective Properties
Mihalj Posa et al.
MOLECULAR PHARMACEUTICS (2017)
Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis
Anna M. Diehl et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
Annika Wahlstrom et al.
CELL METABOLISM (2016)
Global Epidemiology of Nonalcoholic Fatty Liver Disease-Meta-Analytic Assessment of Prevalence, Incidence, and Outcomes
Zobair M. Younossi et al.
HEPATOLOGY (2016)
Small heterodimer partner SHP mediates liver X receptor (LXR)-dependent suppression of inflammatory signaling by promoting LXR SUMOylation specifically in astrocytes
Jee Hoon Lee et al.
Science Signaling (2016)
Small heterodimer partner SHP mediates liver X receptor (LXR)-dependent suppression of inflammatory signaling by promoting LXR SUMOylation specifically in astrocytes
Jee Hoon Lee et al.
Science Signaling (2016)
Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis
Chrysi Koliaki et al.
CELL METABOLISM (2015)
PDIA3 Knockdown Exacerbates Free Fatty Acid-Induced Hepatocyte Steatosis and Apoptosis
Xue-qun Zhang et al.
PLOS ONE (2015)
FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
Prajwal Gurung et al.
JOURNAL OF IMMUNOLOGY (2014)
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
Antonio Ayala et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
Sama I. Sayin et al.
CELL METABOLISM (2013)
The TGR5 receptor mediates bile acid-induced itch and analgesia
Farzad Alemi et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice
Thomas Gautier et al.
JOURNAL OF LIPID RESEARCH (2013)
Diet-Sensitive Sources of Reactive Oxygen Species in Liver Mitochondria: Role of Very Long Chain Acyl-CoA Dehydrogenases
Ariel R. Cardoso et al.
PLOS ONE (2013)
4-Hydroxynonenal Induces Mitochondrial-Mediated Apoptosis and Oxidative Stress in SH-SY5Y Human Neuronal Cells
Sunny O. Abarikwu et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2012)
Nrf2 Inhibits LXRα-Dependent Hepatic Lipogenesis by Competing with FXR for Acetylase Binding
Hee Yeon Kay et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Advanced lipoxidation end-products
Reinald Pamplona
CHEMICO-BIOLOGICAL INTERACTIONS (2011)
Nuclear Factor High-Mobility Group Box1 Mediating the Activation of Toll-Like Receptor 4 Signaling in Hepatocytes in the Early Stage of Nonalcoholic Fatty Liver Disease in Mice
Liang Li et al.
HEPATOLOGY (2011)
Upregulation of scavenger receptor class B type I expression by activation of FXR in hepatocyte
Fan Chao et al.
ATHEROSCLEROSIS (2010)
Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling
Pankaj Chaudhary et al.
BIOCHEMISTRY (2010)
Malondialdehyde-acetaldehyde adduct is the dominant epitope after MDA modification of proteins in atherosclerosis
Michael J. Duryee et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis
Quentin M. Anstee et al.
JOURNAL OF HEPATOLOGY (2010)
Pan-Caspase Inhibitor VX-166 Reduces Fibrosis in an Animal Model of Nonalcoholic Steatohepatitis
Rafal P. Witek et al.
HEPATOLOGY (2009)
Interrelationship between Liver X Receptor α, Sterol Regulatory Element-binding Protein-1c, Peroxisome Proliferator-activated Receptor γ, and Small Heterodimer Partner in the Transcriptional Regulation of Glucokinase Gene Expression in Liver
Tae-Hyun Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells
Abha Sharma et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
4-hydroxynonenal self-limits fas-mediated DISC-Independent apoptosis by promoting export of daxx from the nucleus to the cytosol and its binding to fas
Rajendra Sharma et al.
BIOCHEMISTRY (2008)
Evolution of the bile salt nuclear receptor FXR in vertebrates
Erica J. Reschly et al.
JOURNAL OF LIPID RESEARCH (2008)
Novel potent and selective bile acid derivatives as TGR5 agonists: Biological screening, structure-activity relationships, and molecular modeling studies
Hiroyuki Sato et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Deciphering the mechanism of HNE-induced apoptosis in cultured murine cortical neurons: Transcriptional responses and cellular pathways
Zhao Feng Peng et al.
NEUROPHARMACOLOGY (2007)
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
DE Kleiner et al.
HEPATOLOGY (2005)
Malondialdehyde-acetaldehyde haptenated protein binds macrophage scavenger receptor(s) and induces lysosomal damage
MS Willis et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2004)
Hepatocyte apoptosis and Fas expression are prominent features of human nonalcoholic steatohepatitis
AE Feldstein et al.
GASTROENTEROLOGY (2003)
Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression
T Claudel et al.
GASTROENTEROLOGY (2003)
Structural basis for bile acid binding and activation of the nuclear receptor FXR
LZ Mi et al.
MOLECULAR CELL (2003)
A G protein-coupled receptor responsive to bile acids
Y Kawamata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The small heterodimer partner interacts with the liver X receptor α and represses its transcriptional activity
C Brendel et al.
MOLECULAR ENDOCRINOLOGY (2002)
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
S Seki et al.
JOURNAL OF HEPATOLOGY (2002)
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
SB Joseph et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Role of malondialdehyde-acetaldehyde adducts in liver injury
DJ Tuma
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Malondialdehyde-acetaldehyde-haptenated protein induces cell death by induction of necrosis and apoptosis in immune cells
MS Willis et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2002)
Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-κB-independent, caspase-3-dependent pathway
S Faouzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
B Goodwin et al.
MOLECULAR CELL (2000)
分享论文
