The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin

In this paper, we provide evidence that Zn2+ ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption experiments [1].

Automated summary

In this study, it is demonstrated that Zn2+ ions are involved in the mechanism of SARS-CoV-2 virus evading immune response mediated by the BST2-tetherin host protein, supported by sequence analysis, molecular dynamics simulations, and X-ray absorption experiments.