Ceratoluteolin: A new flavonoid from Salvia ceratophylla from Jordan

Ceratoluteolin 1, a new luteolin derivative was isolated from Salvia Ceratophylla growing wild in Jordan along with other 14 known compounds including two sterols, two triterpenes, four flavonoids and six phenolic compounds, one of which is reported for the first time from Lamiaceae family. The isolated compounds were genkwanin-40-methyl ether 2, b-sitosterol 3, oleanolic acid 4, ursolic acid 5, apigenin 6, b-sitosteryl glucoside 7, p-hydroxyphenyl caffeate 8, caffeic acid 9, shi-mobashiric acid B 10, methyl rosmarinate 11, butyl rosmarinate 12, luteolin 13, luteolin-7-O-glucoside 14 and rosmarinic acid 15. Complete structural verification of the isolated compounds was achieved by careful inspection of their spectral data including NMR (1D & 2D) and HREIMS.(c) 2022 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Automated summary

A new luteolin derivative, Ceratoluteolin 1, was isolated from wild-growing Salvia Ceratophylla in Jordan, along with 14 known compounds including sterols, triterpenes, flavonoids, and phenolic compounds. One of the compounds is reported for the first time from the Lamiaceae family. The structures of the isolated compounds were verified through careful analysis of their spectral data, including NMR and HREIMS.