Carbon-Germanium Bond Formation via Low-Valent Cobalt- Catalyzed Cross-Electrophile Coupling

An efficient, electrochemically induced cobalt -catalyzed carbon-germanium bond formation provides access to a variety of functionalized germane-containing compounds, including aryl, vinyl, and alkyl germanes. The cobalt-catalyzed germylation is conducted under mild reaction conditions and exhibits a broad scope and functional group tolerance. Mechanistic experimental studies provide insight into the unexpected reaction pathway and the sequential activation of the different electrophiles.

Automated summary

An efficient cobalt-catalyzed carbon-germanium bond formation method has been developed, providing access to a wide range of functionalized germane-containing compounds. This method shows a broad scope and good tolerance toward various functional groups, and is conducted under mild reaction conditions. Mechanistic studies shed light on the unexpected reaction pathway and sequential activation of different electrophiles.