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Jasmin Weisemann et al.
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CURRENT OPINION IN STRUCTURAL BIOLOGY (2015)
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Ornella Rossetto et al.
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Structure of dual receptor binding to botulinum neurotoxin B
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REFMAC5 for the refinement of macromolecular crystal structures
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MolProbity: all-atom structure validation for macromolecular crystallography
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PHENIX: a comprehensive Python-based system for macromolecular structure solution
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Jiafu Wang et al.
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M Dong et al.
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S Mahrhold et al.
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Daniel D. Truong et al.
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JE Keller et al.
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PG Foran et al.
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