相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Whole-genome sequencing reveals host factors underlying critical COVID-19
Athanasios Kousathanas et al.
NATURE (2022)
Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease
Mary E. Keir et al.
JOURNAL OF IMMUNOLOGY (2021)
Single-cell analyses of Crohn's disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions
Natalia Jaeger et al.
NATURE COMMUNICATIONS (2021)
Ultra-high Magnification Endocytoscopy and Molecular Markers for Defining Endoscopic and Histologic Remission in Ulcerative Colitis - An Exploratory Study to Define Deep Remission
Marietta Iacucci et al.
INFLAMMATORY BOWEL DISEASES (2021)
Randomized Controlled Trial Substudy of Cell-specific Mechanisms of Janus Kinase 1 Inhibition With Upadacitinib in the Crohn's Disease Intestinal Mucosa: Analysis From the CELEST Study
Daniel Aguilar et al.
INFLAMMATORY BOWEL DISEASES (2021)
Targeting ITK signaling for T cell-mediated diseases
Samuel Weeks et al.
ISCIENCE (2021)
The Human Gene Mutation Database (HGMD(R)): optimizing its use in a clinical diagnostic or research setting
Peter D. Stenson et al.
HUMAN GENETICS (2020)
Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets
Kyle Gettler et al.
GENES AND IMMUNITY (2019)
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
Jerome C. Martin et al.
CELL (2019)
CADD: predicting the deleteriousness of variants throughout the human genome
Philipp Rentzsch et al.
NUCLEIC ACIDS RESEARCH (2019)
Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis
Patrick Maffucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Targeting Endothelial Ligands: ICAM-1/alicaforsen, MAdCAM-1
Walter Reinisch et al.
JOURNAL OF CROHNS & COLITIS (2018)
Integrating single-cell transcriptomic data across different conditions, technologies, and species
Andrew Butler et al.
NATURE BIOTECHNOLOGY (2018)
Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease
Ken Y. Hui et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
Manuel A. Rivas et al.
PLOS GENETICS (2018)
Toll-like Receptors and inflammatory Bowel Disease
Yue Lu et al.
FRONTIERS IN IMMUNOLOGY (2018)
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Hailiang Huang et al.
NATURE (2017)
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de lange et al.
NATURE GENETICS (2017)
The ST2/IL-33 Axis in immune Cells during inflammatory Diseases
Brad Griesenauer et al.
FRONTIERS IN IMMUNOLOGY (2017)
RGS proteins as targets in the treatment of intestinal inflammation and visceral pain: New insights and future perspectives
Maciej Salaga et al.
BIOESSAYS (2016)
SHIP1 Deficiency in Human IBD: Molecular Basis, Prognosis and Agonist Development
William Kerr et al.
INFLAMMATORY BOWEL DISEASES (2016)
The mutation significance cutoff: gene-level thresholds for variant predictions
Yuval Itan et al.
NATURE METHODS (2016)
Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage
Aziz Belkadi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Emerging roles of Egr2 and Egr3 in the control of systemic autoimmunity
Kaoru Morita et al.
RHEUMATOLOGY (2016)
The Ensembl Variant Effect Predictor
William McLaren et al.
GENOME BIOLOGY (2016)
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
Bjarni J. Vilhjalmsson et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
Exome Sequencing Analysis Reveals Variants in Primary Immunodeficiency Genes in Patients With Very Early Onset Inflammatory Bowel Disease
Judith R. Kelsen et al.
GASTROENTEROLOGY (2015)
Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015
Capucine Picard et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2015)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Jimmy Z. Liu et al.
NATURE GENETICS (2015)
Understanding multicellular function and disease with human tissue-specific networks
Casey S. Greene et al.
NATURE GENETICS (2015)
NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data
Jianguo Xia et al.
NATURE PROTOCOLS (2015)
TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits
Dorothee Diogo et al.
PLOS ONE (2015)
The human gene damage index as a gene-level approach to prioritizing exome variants
Yuval Itan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants
Aziz Belkadi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Second-generation PLINK: rising to the challenge of larger and richer datasets
Christopher C. Chang et al.
GIGASCIENCE (2015)
HTSeq-a Python framework to work with high-throughput sequencing data
Simon Anders et al.
BIOINFORMATICS (2015)
Causal analysis approaches in Ingenuity Pathway Analysis
Andreas Kraemer et al.
BIOINFORMATICS (2014)
RAREMETAL: fast and powerful meta-analysis for rare variants
Shuang Feng et al.
BIOINFORMATICS (2014)
fastSTRUCTURE: Variational Inference of Population Structure in Large SNP Data Sets
Anil Raj et al.
GENETICS (2014)
Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data
Guo-Bo Chen et al.
HUMAN MOLECULAR GENETICS (2014)
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Yael Haberman et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3
Aditya Murthy et al.
NATURE (2014)
Searching for missing heritability: Designing rare variant association studies
Or Zuk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
The population genetics of the Jewish people
Harry Ostrer et al.
HUMAN GENETICS (2013)
InnateDB: systems biology of innate immunity and beyond-recent updates and continuing curation
Karin Breuer et al.
NUCLEIC ACIDS RESEARCH (2013)
The human gene connectome as a map of short cuts for morbid allele discovery
Yuval Itan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
Daehwan Kim et al.
GENOME BIOLOGY (2013)
Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies
Seunggeun Lee et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3
Pablo Cingolani et al.
FLY (2012)
Intestinal expression of SHIP in inflammatory bowel diseases
Ingrid Arijs et al.
GUT (2012)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
Cole Trapnell et al.
NATURE PROTOCOLS (2012)
A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci
Eimear E. Kenny et al.
PLOS GENETICS (2012)
GCTA: A Tool for Genome-wide Complex Trait Analysis
Jian Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
PredictABEL: an R package for the assessment of risk prediction models
Suman Kundu et al.
EUROPEAN JOURNAL OF EPIDEMIOLOGY (2011)
Cutting Edge: Regulator of G Protein Signaling-1 Selectively Regulates Gut T Cell Trafficking and Colitic Potential
Deena L. Gibbons et al.
JOURNAL OF IMMUNOLOGY (2011)
Abraham's Children in the Genome Era: Major Jewish Diaspora Populations Comprise Distinct Genetic Clusters with Shared Middle Eastern Ancestry
Gil Atzmon et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2010)
Robust relationship inference in genome-wide association studies
Ani Manichaikul et al.
BIOINFORMATICS (2010)
Characterization of the Novel ST2/IL-33 System in Patients with Inflammatory Bowel Disease
Carol J. Beltran et al.
INFLAMMATORY BOWEL DISEASES (2010)
ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems
Vivek Kaimal et al.
NUCLEIC ACIDS RESEARCH (2010)
Review: Anti-adhesion molecule therapy for inflammatory bowel disease
Subrata Ghosh et al.
Therapeutic Advances in Gastroenterology (2010)
Fast and accurate short read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2009)
Ulcerative Colitis Induces Changes on the Expression of the Endocannabinoid System in the Human Colonic Tissue
Lucia Marquez et al.
PLOS ONE (2009)
The ATG16L1 Gene Variants rs2241879 and rs2241880 (T300A) Are Strongly Associated With Susceptibility to Crohn's Disease in the German Population
Jurgen Glas et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2008)
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
AP Cuthbert et al.
GASTROENTEROLOGY (2002)