4.8 Article

Impact of diet and host genetics on the murine intestinal mycobiome

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Microbiology

The human symbiont Bacteroides thetaiotaomicron promotes diet-induced obesity by regulating host lipid metabolism

Sang-Hyun Cho et al.

Summary: The gut microbiome has a significant impact on lipid metabolism. The symbiotic bacteria Bacteroides thetaiotaomicron exacerbates metabolic disorders by promoting lipid digestion and absorption, as well as regulating iron storage, leading to increased fat deposition and impaired glucose tolerance.

JOURNAL OF MICROBIOLOGY (2022)

Article Genetics & Heredity

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

Esteban A. Lopera-Maya et al.

Summary: Host genetics influence the gut microbiome, with the LCT and ABO genes showing significant associations with microbial composition and function. The associations at the LCT locus are modulated by lactose intake, while those at ABO can be explained by participant secretor status determined by their FUT2 genotype. Further loci also show potential associations with microbial taxa and pathways. Larger sample sizes are needed to fully understand the effects of host genetics on the gut microbiome.

NATURE GENETICS (2022)

Article Biochemistry & Molecular Biology

Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions

Lian Narunsky-Haziza et al.

Summary: This study comprehensively characterizes the cancer mycobiome in cancer patients and finds low abundances of fungi in various human cancers. The composition of fungal communities differs among cancer types and they are frequently associated with cancer cells and macrophages spatially. Comparisons with bacterial and immune communities reveal co-occurring bi-domain ecologies and distinct immune responses. The tissue and plasma mycobiomes show prognostic and diagnostic capabilities even in early stage cancers, and synergistic predictive performance with bacterial communities.
Article Biochemistry & Molecular Biology

A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors

Anders B. Dohlman et al.

Summary: Fungal microorganisms, particularly Candida, play a significant role in the pathogenesis of gastrointestinal cancers, including lung, stomach, and colon cancers. Their presence is associated with immune response, metastatic disease, and decreased survival, suggesting that tumor-associated fungal DNA may serve as diagnostic or prognostic biomarkers.
Article Medicine, Research & Experimental

Next-generation sequencing: insights to advance clinical investigations of the microbiome

Caroline R. Wensel et al.

Summary: This Review discusses the advancements in NGS technology for studying the human microbiome, including the pros and cons of different NGS methodologies and important concepts in data variability and study design. Examples of NGS studies on the human microbiome in diverse clinical contexts are provided, as well as insights into the future integration and advancement of NGS in microbiome research and clinical care.

JOURNAL OF CLINICAL INVESTIGATION (2022)

Article Genetics & Heredity

Large-scale association analyses identify host factors influencing human gut microbiome composition

Alexander Kurilshikov et al.

Summary: The study revealed significant effects of host genetic variation on microbial composition, with the lactase (LCT) gene locus showing an age-dependent association with Bifidobacterium abundance. Other associations, while suggestive, were enriched for taxa with high heritability and for genes expressed in the intestine and brain.

NATURE GENETICS (2021)

Review Genetics & Heredity

The complexities of the diet-microbiome relationship: advances and perspectives

Emily R. Leeming et al.

Summary: Personalised dietary modulation of the gut microbiota is crucial for disease management, but the current understanding and application of this concept are still limited. Improved collection of dietary data and further characterization of mechanistic interactions are needed for a detailed understanding of diet-microbiota relations.

GENOME MEDICINE (2021)

Article Biochemistry & Molecular Biology

Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies

Itai Doron et al.

Summary: This study reveals the important role of gut commensal fungi in shaping the human antibody repertoire through CARD9-dependent induction of host-protective antifungal IgG. Candida albicans is the major inducer of antifungal immunoglobulin G (IgG) and provides protection against disseminated candidiasis.
Article Nutrition & Dietetics

The intestinal mycobiota and its relationship with overweight, obesity and nutritional aspects

Ricardo Garcia-Gamboa et al.

Summary: This study found that specific types and concentrations of fungal communities in obese individuals are related to the development of obesity, and showed correlations with weight, fat mass, and other biochemical indicators.

JOURNAL OF HUMAN NUTRITION AND DIETETICS (2021)

Review Immunology

Viral Infections, the Microbiome, and Probiotics

Ashton Harper et al.

Summary: Viral infections continue to pose significant global morbidity and mortality, with factors such as climate change, increased mobility of people and goods, and disruptions in the gastrointestinal microbiome all playing a role. Understanding the complex relationship between the microbiome, viral immunity, and host physiology is crucial for developing effective prevention and treatment strategies for viral diseases.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Article Cell & Tissue Engineering

Gut microbiota is associated with bone mineral density

Bolun Cheng et al.

Bone & Joint Research (2021)

Review Microbiology

Mixed biofilms of pathogenic Candida-bacteria: regulation mechanisms and treatment strategies

Fazlurrahman Khan et al.

Summary: Mixed-species biofilms, particularly those formed by Candida and bacterial species, pose significant clinical challenges due to their increased resistance to antimicrobial drugs. This review discusses the clinical significance and signaling mechanisms of Candida-bacteria interactions in mixed biofilms, and offers possible therapeutic approaches to combat infections associated with them.

CRITICAL REVIEWS IN MICROBIOLOGY (2021)

Article Microbiology

Fungi of the human gut microbiota: Roles and significance

J. Christian Perez

Summary: Fungi are important components of the gut microbiota and can influence the host's health by affecting immune responses. Further research on the fungi inhabiting the human body is needed to understand how the microbiota contribute to health and disease.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2021)

Editorial Material Medicine, General & Internal

Fungal microbiome and multiple sclerosis: The not-so-new kid on the block

Ashutosh K. Mangalam

EBIOMEDICINE (2021)

Article Biology

The gut commensal fungus, Candida parapsilosis, promotes high fat-diet induced obesity in mice

Shanshan Sun et al.

Summary: The study found that the gut commensal Candida parapsilosis is a causative fungus for the development of high fat-diet induced obesity in mice, highlighting the therapeutic strategy targeting gut fungi. In addition, the results suggest that fungi could represent possible targets for combating obesity.

COMMUNICATIONS BIOLOGY (2021)

Review Immunology

Role and Mechanism of Gut Microbiota in Human Disease

Yinwei Chen et al.

Summary: The human gut microbiome plays a crucial role in human health, and dysbiosis may lead to various chronic diseases. The mechanisms of its impact on neurodegenerative diseases, cardiovascular diseases, metabolic diseases, and gastrointestinal diseases are extremely complex.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Review Biochemistry & Molecular Biology

GRAMD1-mediated accessible cholesterol sensing and transport

Tomoki Naito et al.

Summary: This study discusses the importance of accessible cholesterol in cells and how the endoplasmic reticulum monitors the cholesterol levels on the plasma membrane. It highlights the role of GRAMD1s proteins in facilitating the transport of cholesterol from the plasma membrane to the ER.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2021)

Article Cell Biology

Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4

Thomas Kleiber et al.

Summary: The inactivation of Taf4 in adult murine pancreatic beta cells affects the expression of critical genes involved in beta-cell function, leading to defects in insulin secretion and increased blood sugar levels. Single-cell RNA-seq analysis revealed a population of cells starting to trans-differentiate into alpha-like cells after Taf4-loss.

CELL DEATH & DISEASE (2021)

Review Genetics & Heredity

Genetic Susceptibility to Fungal Infections and Links to Human Ancestry

Bharati Naik et al.

Summary: Fungi have formed symbiotic relationships with different parts of the human body over time, and certain factors can trigger their transition to a pathogenic state. Host genetics play a crucial role in fungal infection, influencing the recognition between pathogen-associated molecular patterns and host pattern recognition receptor molecules through mutations.

FRONTIERS IN GENETICS (2021)

Article Medicine, General & Internal

Association of Insulin Resistance and Type 2 Diabetes With Gut Microbial Diversity A Microbiome-Wide Analysis From Population Studies

Zhangling Chen et al.

Summary: This study found that higher microbiome alpha diversity, as well as more butyrate-producing gut bacteria, were associated with lower incidence of type 2 diabetes and reduced levels of insulin resistance in individuals without diabetes, providing insights into the etiology, pathogenesis, and potential treatment of type 2 diabetes.

JAMA NETWORK OPEN (2021)

Article Microbiology

ITS2 Sequencing and Targeted Meta-Proteomics of Infant Gut Mycobiome Reveal the Functional Role of Rhodotorula sp. during Atopic Dermatitis Manifestation

Kevin Mok et al.

Summary: The study found that infants with persistent atopic dermatitis had higher diversity in their fungal microbiome, while those who recovered had a more diverse microbiome. Specific fungi were selected as markers from each group, showing differences in fungal species and abundance among the groups. Metaproteomic analysis revealed higher abundance of fungal proteins, particularly from Rhodotorula sp., in the group with persistent symptoms. Unique proteins from Rhodotorula sp., such as RAN-binding protein 1 and glycerol kinase, were suggested to be related to the manifestation of atopic dermatitis in infants.

JOURNAL OF FUNGI (2021)

Article Computer Science, Interdisciplinary Applications

The Inflammatory Bowel Disease Transcriptome and Metatranscriptome Meta-Analysis (IBD TaMMA) framework

Luca Massimino et al.

Summary: Massimino et al. propose the Inflammatory Bowel Disease Transcriptome and Metatranscriptome Meta-Analysis (IBD TaMMA) framework, an open-source platform for expediting the investigation of IBD-specific transcriptomics and metatranscriptomics signatures.

NATURE COMPUTATIONAL SCIENCE (2021)

Review Dentistry, Oral Surgery & Medicine

Anticandidal Activities by Lactobacillus Species: An Update on Mechanisms of Action

Roberto Vazquez-Munoz et al.

Summary: Lactobacilli, as probiotics, can provide various benefits to the host, including antifungal effects that can help prevent Candida infections. The mechanisms of action of Lactobacillus spp. against Candida remain largely unexplored, and this work aims to comprehensively review and update current knowledge on these mechanisms.

FRONTIERS IN ORAL HEALTH (2021)

Article Gastroenterology & Hepatology

The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn's Disease Patients in Remission and in Individuals Without Gastrointestinal Inflammation

Andrew Nelson et al.

Summary: Comparative analysis of fecal mycobiota in patients with CD and non-CD subjects revealed compositional changes in the gut mycobiota of CD patients, suggesting a potential role of fungi in the pathogenesis of CD. No NOD2 genotype-specific differences were observed in the fecal mycobiota.

JOURNAL OF CROHNS & COLITIS (2021)

Review Gastroenterology & Hepatology

Diet and the Human Gut Microbiome: An International Review

Annette S. Wilson et al.

DIGESTIVE DISEASES AND SCIENCES (2020)

Article Allergy

The microbiome and inflammatory bowel disease

Kerri L. Glassner et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Editorial Material Rheumatology

Microbiota, metabolism and lupus in mice

Joanna Clarke

NATURE REVIEWS RHEUMATOLOGY (2020)

Article Multidisciplinary Sciences

Health and disease markers correlate with gut microbiome composition across thousands of people

Ohad Manor et al.

NATURE COMMUNICATIONS (2020)

Review Immunology

Host-microbiota interactions in inflammatory bowel disease

Roberta Caruso et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Biochemical Research Methods

FastSpar: rapid and scalable correlation estimation for compositional data

Stephen C. Watts et al.

BIOINFORMATICS (2019)

Article Microbiology

Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models

Jose J. Limon et al.

CELL HOST & MICROBE (2019)

Article Infectious Diseases

Coexistence of Candida species and bacteria in patients with cystic fibrosis

Johanna Haiko et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2019)

Review Oncology

Modulating the microbiome to improve therapeutic response in cancer

Jennifer L. McQuade et al.

LANCET ONCOLOGY (2019)

Review Microbiology

Fungal-Bacterial Interactions in Health and Disease

Wibke Krueger et al.

PATHOGENS (2019)

Review Microbiology

Diet-microbiota interactions and personalized nutrition

Aleksandra A. Kolodziejczyk et al.

NATURE REVIEWS MICROBIOLOGY (2019)

Article Genetics & Heredity

Genetic determinants of gut microbiota composition and bile acid profiles in mice

Ulia H. Kemis et al.

PLOS GENETICS (2019)

Article Multidisciplinary Sciences

The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL

Berk Aykut et al.

NATURE (2019)

Article Multidisciplinary Sciences

Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line

Artem Vorobyev et al.

NATURE COMMUNICATIONS (2019)

Article Gastroenterology & Hepatology

Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer

Olabisi Oluwabukola Coker et al.

Editorial Material Rheumatology

The microbiome in SLE pathogenesis

Gregg J. Silverman

NATURE REVIEWS RHEUMATOLOGY (2019)

Review Allergy

Innate and adaptive immune responses to fungi in the airway

Kathleen R. Bartemes et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Review Microbiology

The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis

Raphael Enaud et al.

MICROORGANISMS (2018)

Article Gastroenterology & Hepatology

Fungal microbiota dysbiosis in IBD

Harry Sokol et al.

Review Immunology

Fungi in the healthy human gastrointestinal tract

Heather E. Hallen-Adams et al.

VIRULENCE (2017)

Article Multidisciplinary Sciences

Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage

Carina de Lima Buzzo et al.

SCIENTIFIC REPORTS (2017)

Article Gastroenterology & Hepatology

Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn's Disease Patients

Giuseppina Liguori et al.

JOURNAL OF CROHNS & COLITIS (2016)

Article Microbiology

Immunological Consequences of Intestinal Fungal Dysbiosis

Matthew L. Wheeler et al.

CELL HOST & MICROBE (2016)

Review Allergy

Allergic Fungal Airway Disease

E. M. Rick et al.

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY (2016)

Article Microbiology

Age and Gender Affect the Composition of Fungal Population of the Human Gastrointestinal Tract

Francesco Strati et al.

FRONTIERS IN MICROBIOLOGY (2016)

Article Multidisciplinary Sciences

VSEARCH: a versatile open source tool for metagenomics

Torbjorn Rognes et al.

Article Endocrinology & Metabolism

Dietary fat and gut microbiota interactions determine diet-induced obesity in mice

Raphaela Kuebeck et al.

MOLECULAR METABOLISM (2016)

Article Microbiology

Candida-Bacteria Interactions: Their Impact on Human Disease

Devon L. Allison et al.

MICROBIOLOGY SPECTRUM (2016)

Article Dermatology

First reported case of Aspergillus nidulans eumycetoma in a sporotrichoid distribution

Rajesh Verma et al.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2015)

Article Biochemistry & Molecular Biology

TCF7L2 is a master regulator of insulin production and processing

Yuedan Zhou et al.

HUMAN MOLECULAR GENETICS (2014)

Editorial Material Dermatology

Zygomycetes: an emerging problem in the clinical laboratory Preface

Sybren de Hoog et al.

MYCOSES (2014)

Article Genetics & Heredity

Quantitative Trait Locus Mapping Methods for Diversity Outbred Mice

Daniel M. Gatti et al.

G3-GENES GENOMES GENETICS (2014)

Article Biochemical Research Methods

Waste Not, Want Not: Why Rarefying Microbiome Data Is Inadmissible

Paul J. McMurdie et al.

PLOS COMPUTATIONAL BIOLOGY (2014)

Article Gastroenterology & Hepatology

Higher Activity of the Inducible Nitric Oxide Synthase Contributes to Very Early Onset Inflammatory Bowel Disease

Sandeep S. Dhillon et al.

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2014)

Article Multidisciplinary Sciences

Fungi of the Murine Gut: Episodic Variation and Proliferation during Antibiotic Treatment

Serena Dollive et al.

PLOS ONE (2013)

Article Infectious Diseases

Endemic Mycoses in Immunocompromised Hosts

Trent R. Malcolm et al.

CURRENT INFECTIOUS DISEASE REPORTS (2013)

Review Allergy

Fungi and allergic lower respiratory tract diseases

Alan P. Knutsen et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

Article Multidisciplinary Sciences

Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits

Autumn M. McKnite et al.

PLOS ONE (2012)

Article Allergy

A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma

Lisa G. Wood et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)

Review Microbiology

Melanized Fungi in Human Disease

Sanjay G. Revankar et al.

CLINICAL MICROBIOLOGY REVIEWS (2010)

Letter Biochemical Research Methods

QIIME allows analysis of high-throughput community sequencing data

J. Gregory Caporaso et al.

NATURE METHODS (2010)

Review Microbiology

Medically important bacterial-fungal interactions

Anton Y. Peleg et al.

NATURE REVIEWS MICROBIOLOGY (2010)

Article Multidisciplinary Sciences

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

Andrew K. Benson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Genetics & Heredity

PLINK: A tool set for whole-genome association and population-based linkage analyses

Shaun Purcell et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Biotechnology & Applied Microbiology

Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy

Qiong Wang et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)

Article Genetics & Heredity

TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis

Stephane Cauchi et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2007)

Review Microbiology

Origins and significance of ergot alkaloid diversity in fungi

DG Panaccione

FEMS MICROBIOLOGY LETTERS (2005)

Article Biochemical Research Methods

R/qtl: QTL mapping in experimental crosses

KW Broman et al.

BIOINFORMATICS (2003)

Article Biochemistry & Molecular Biology

Cytoscape: A software environment for integrated models of biomolecular interaction networks

P Shannon et al.

GENOME RESEARCH (2003)

Article Multidisciplinary Sciences

A method for fine mapping quantitative trait loci in outbred animal stocks

R Mott et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)