4.7 Article

The ER Protein Translocation Channel Subunit Sbh1 Controls Virulence of Cryptococcus neoformans

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Summary: Cryptococcus genus consists of two primary species complexes that are important human fungal pathogens, leading to various manifestations in humans, most commonly affecting the pulmonary or central nervous system. Knowledge about Cryptococcus mainly comes from experiments and animal models, but fails to fully replicate human conditions. Understanding genetic and phenotypic differences in human infections is crucial for identifying risk factors contributing to pathogenesis and clinical outcomes associated with cryptococcal strains.

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