Establishment and Application of a Triplex Real-Time RT-PCR Assay for Differentiation of PEDV, PoRV, and PDCoV

Article Infectious Diseases

Development and application of a duplex real-time PCR assay for differentiation of genotypes I and II African swine fever viruses

Xiangdong Li et al.

Summary: The established duplex real-time PCR method in this study provides a powerful tool for rapid detection and differentiation between genotypes I and II ASFVs, which is of great importance for the effective control of ASFV.

TRANSBOUNDARY AND EMERGING DISEASES (2022)

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Article Virology

Co-infection of porcine deltacoronavirus and porcine epidemic diarrhoea virus alters gut microbiota diversity and composition in the colon of piglets

Xiangli Shu et al.

Summary: Porcine deltacoronavirus (PDCoV) and porcine epidemic diarrhoea virus (PEDV) co-infection alters the composition of the intestinal microbiota and exacerbates the severity of the disease in piglets.

VIRUS RESEARCH (2022)

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Article Virology

Genetic Diversity of Porcine Group A Rotavirus Strains from Pigs in South Korea

Gyu-Nam Park et al.

Summary: This study investigated the prevalence and genetic characteristics of porcine group A rotavirus (PoRVA) in domestic pig farms in South Korea. Multiple predominant circulating genotypes were identified, providing valuable epidemiological information for the development of vaccines targeting the current strains.

VIRUSES-BASEL (2022)

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Article Virology

Development of a Genetically Engineered Bivalent Vaccine against Porcine Epidemic Diarrhea Virus and Porcine Rotavirus

Wan Li et al.

Summary: In this paper, a bivalent vaccine against PEDV and PoRV was developed and shown to be effective in preventing infections and improving piglet survival rates.

VIRUSES-BASEL (2022)

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Review Virology

Prevention and Control of Porcine Epidemic Diarrhea: The Development of Recombination-Resistant Live Attenuated Vaccines

Xiaoyu Niu et al.

Summary: Porcine epidemic diarrhea (PED) caused by PED virus (PEDV) is a highly contagious enteric disease that has caused significant economic losses to the pork industry. Vaccination with live attenuated vaccines (LAVs) is the most effective strategy, but there are no safe and effective vaccines available yet. This article summarizes the current status and obstacles in PEDV LAV development and discusses strategies to prevent the reversion of LAVs.

VIRUSES-BASEL (2022)

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Review Virology

Porcine Epidemic Diarrhea Virus: An Updated Overview of Virus Epidemiology, Virulence Variation Patterns and Virus-Host Interactions

Yuanzhu Zhang et al.

Summary: This article reviews the latest progress in the biology of PEDV, including its transmission and origin, structure and function, evolution, and virus-host interaction, in an attempt to find potential virulence factors influencing PEDV pathogenesis. The findings serve as a valuable reference for the development of vaccines and control of infection.

VIRUSES-BASEL (2022)

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Review Microbiology

Rotavirus Infection in Swine: Genotypic Diversity, Immune Responses, and Role of Gut Microbiome in Rotavirus Immunity

Deepak Kumar et al.

Summary: Rotaviruses are common in swine populations and can cause significant impact, especially in newborn piglets. Boosting lactogenic immunity in gilts is currently the main method to prevent RV infections in piglets. The diversity of RV species in swine contributes to the challenges in preventing RV diarrhea.

PATHOGENS (2022)

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Article Infectious Diseases

Development and application of a quadruplex real-time PCR assay for differential detection of porcine circoviruses (PCV1 to PCV4) in Jiangsu province of China from 2016 to 2020

Nanhua Chen et al.

Summary: There are four species of porcine circoviruses (PCVs) and a quadruplex real-time PCR assay has been developed in this study to differentiate PCV1-4 with satisfactory results. The assay showed 100% agreement with conventional PCR assays when applied to clinical samples from Jiangsu province in China, confirming the coexistence of all species of PCV1-4 strains in recent years.

TRANSBOUNDARY AND EMERGING DISEASES (2021)

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Review Virology

Porcine Coronaviruses: Overview of the State of the Art

Hanna Turlewicz-Podbielska et al.

Summary: Coronaviruses exhibit high mutation rates and recombine easily, enabling them to overcome species barriers. Six CoV can infect pigs, with different strains causing various diseases. Control of CoV infections in pigs requires rapid diagnostics and focus on biosecurity.

VIROLOGICA SINICA (2021)

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Article Infectious Diseases