Autocrine amphiregulin signaling sustains castration-resistant Ly6d(+) prostate cancer cells

Mechanisms underlying the devel-opment of castration-resistant prostate cancer (CRPC) remain in-completely understood. A recent study by Steiner et al. shows that Ly6d(+) prostate tumor cells survive androgen deprivation through an autocrine amphiregulin signaling pathway.

Automated summary

A recent study by Steiner et al. reveals that Ly6d(+) prostate tumor cells can survive after castration through an autocrine amphiregulin signaling pathway.