Developing protein structure figures

Review Biochemistry & Molecular Biology

Cytoplasmic gene expression: lessons from poxviruses

Clemens Grimm et al.

Summary: Poxviruses utilize a virus-encoded RNA polymerase in the host cytoplasm to transcribe their DNA genome, unlike other viruses that transfer their genome to the host nucleus. Recent high-resolution structures and biochemical data have allowed the definition of a comprehensive model for poxviral gene expression and its regulation.

TRENDS IN BIOCHEMICAL SCIENCES (2022)

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Review Biochemistry & Molecular Biology

Roles of zinc-binding domain of bacterial RNA polymerase in transcription

Yangbo Hu et al.

Summary: This review summarizes recent progress on the regulatory roles of the zinc-binding domain (ZBD) located at the N terminus of the largest subunit beta' in bacterial RNA polymerase in transcription.

TRENDS IN BIOCHEMICAL SCIENCES (2022)

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Article Biochemistry & Molecular Biology

UCSF ChimeraX: Structure visualization for researchers, educators, and developers

Eric F. Pettersen et al.

Summary: UCSF ChimeraX is a powerful visualization program with enhanced performance and graphics, offering new tools and analysis features, support for various areas like virtual reality, and improved ease of use, along with an app store for researchers to contribute new tools.

PROTEIN SCIENCE (2021)

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Letter Multidisciplinary Sciences

Non-trivial role of internal climate feedback on interglacial temperature evolution

Xu Zhang et al.

NATURE (2021)

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Review Biochemistry & Molecular Biology

Direct Structural Insights into GABAA Receptor Pharmacology

Jeong Joo Kim et al.

Summary: GABAA receptors are important in mediating fast neuronal inhibition in the brain and have rich pharmacology. Recent efforts in structural biology have provided insights into how important drug classes and natural products interact with these receptors, laying a foundation for drug design. The focus has been on subunit assemblies of the receptor found at synapses.

TRENDS IN BIOCHEMICAL SCIENCES (2021)

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Editorial Material Biochemistry & Molecular Biology

More Than Just Closed and Open: Unraveling a Mechanosensor

Vanessa J. Flegler et al.

Summary: The bacterial mechanosensitive channel of small conductance (MscS) enters a desensitized state when it loses all coordinated lipids under membrane tension, as visualized in a recent study by Zhang et al.

TRENDS IN BIOCHEMICAL SCIENCES (2021)

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Article Biochemistry & Molecular Biology