Plasmapheresis in ABO incompatible kidney transplant

In patients with an end-stage renal disease, dialysis a or kidney transplant are required to prolong live. For survival of the transplanted kidney, besides the HLA-system, the ABO blood type of donor and patient is also of importance. When the donor organ is derived from a living donor, time can be available prior to the transplant to reduce blood type AB antibodies in case of ABO major incompatibility between organ donor and recipient by double filtration apheresis.

Automated summary

For patients with end-stage renal disease, dialysis or kidney transplant is necessary for prolonging life. In addition to the HLA system, the ABO blood type of the donor and patient is also crucial for the survival of the transplanted kidney. When the organ is donated by a living donor, double filtration apheresis can be used before transplantation to reduce AB antibodies in cases of ABO major incompatibility.