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HAEMOPHILIA (2021)
Prediction of the haemostatic effects of bypassing therapy using comprehensive coagulation assays in emicizumab prophylaxis-treated haemophilia A patients with inhibitors
Shoko Furukawa et al.
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Emicizumab improves the stability and structure of fibrin clot derived from factor VIII-deficient plasma, similar to the addition of factor VIII
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Assaf A. Barg et al.
BRITISH JOURNAL OF HAEMATOLOGY (2020)
Laboratory monitoring of hemophilia A treatments: new challenges
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Rescue factor VIII replacement to secure hemostasis in a patient with hemophilia A and inhibitors on emicizumab prophylaxis undergoing hip replacement
Elena Santagostino et al.
HAEMATOLOGICA (2019)
Use of global assays to monitor emicizumab prophylactic therapy in patients with haemophilia A with inhibitors
Donald F. Brophy et al.
HAEMOPHILIA (2019)
Intrinsic differences between FVIIIa mimetic bispecific antibodies and FVIII prevent assignment of FVIII-equivalence
Nina C. Leksa et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2019)
Effects and Interferences of Emicizumab, a Humanised Bispecific Antibody Mimicking Activated Factor VIII Cofactor Function, on Coagulation Assays
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THROMBOSIS AND HAEMOSTASIS (2019)
Global coagulation function assessed by rotational thromboelastometry predicts coagulation-steady state in individual hemophilia A patients receiving emicizumab prophylaxis
Koji Yada et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2019)
Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study
Steven W. Pipe et al.
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A multicenter, open-label phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors
Guy Young et al.
BLOOD (2019)
Spotlight on emicizumab in the management of hemophilia A: patient selection and special considerations
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Management of perioperative hemostasis in a severe hemophilia A patient with inhibitors on emicizumab using global hemostasis assays
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Use of thrombin generation assay to personalize treatment of breakthrough bleeds in a patient with hemophilia and inhibitors receiving prophylaxis with emicizumab
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HAEMATOLOGICA (2018)
Modified clot waveform analysis to measure plasma coagulation potential in the presence of the anti-factor IXa/factor X bispecific antibody emicizumab
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JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2018)
In vitro studies show synergistic effects of a procoagulant bispecific antibody and bypassing agents
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JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2018)
Thrombodynamics, a new global coagulation test: Measurement of heparin efficiency
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TALANTA (2018)
A contemporary look at FVIII inhibitor development: still a great influence on the evolution of hemophilia therapies
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Use of thrombin generation assay to personalize treatment of breakthrough bleeds in a patient with hemophilia and inhibitors receiving prophylaxis with emicizumab
Yesim Dargaud et al.
HAEMATOLOGICA (2018)
Emicizumab Prophylaxis in Patients Who Have Hemophilia A without Inhibitors
J. Mahlangu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
A Pharmacometric Approach to Substitute for a Conventional Dose-Finding Study in Rare Diseases: Example of Phase III Dose Selection for Emicizumab in Hemophilia A
Koichiro Yoneyama et al.
CLINICAL PHARMACOKINETICS (2018)
Development of Shiny app tools to simplify and standardize the analysis of hemostasis assay data: communication from the SSC of the ISTH
C. Longstaff
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2017)
Emicizumab Prophylaxis in Hemophilia A with Inhibitors
Johannes Oldenburg et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?
Peter J. Lenting et al.
BLOOD (2017)
Factor VIII-Mimetic Function of Humanized Bispecific Antibody in Hemophilia A
Midori Shima et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
An international study on the standardization of fibrin clot permeability measurement: methodological considerations and implications for healthy control values
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JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)
A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model
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Monitoring thrombin generation: Is addition of corn trypsin inhibitor needed?
Henri M. H. Spronk et al.
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Alisa S. Wolberg
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