期刊
THORACIC AND CARDIOVASCULAR SURGEON
卷 -, 期 -, 页码 -出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/a-2052-8912
关键词
gastrointestinal bleeding; fecal occult blood; fecal immunochemical test; colorectal cancer
We investigated the role of preoperative fecal immunochemical test (FIT) for detecting gastrointestinal bleeding and cancer in cardiac surgery. The study found that FIT has limited impact on identification of bleeding sites, but may be useful in detecting malignant lesions.
Background Concerns of gastrointestinal (GI) bleeding after cardiac surgery are increasing with increased use of antiplatelets and anticoagulants. We investigated the roles of preoperative screening for fecal occult blood by fecal immunochemical test ( FIT) widely used to detect GI bleeding and cancer. Methods A retrospective review was done in 1,663 consecutive patients undergoing FIT before cardiac surgery between years 2012 and 2020. One or two rounds of FITwere performed 2 to 3 weeks before surgery, when antiplatelets and anticoagulants were not suspended yet. Results Positive FIT (> 30 mu g of hemoglobin/g of feces) was observed in 227 patients ( 13.7%). Preoperative risk factors for positive FIT included age > 70 years, anticoagulants, and chronic kidney disease. Of those with positive FIT, 180 patients (79%) received preoperative endoscopy, including gastroscopy (n = 139), colonoscopy ( n = 9), and both (n = 32), with no findings of bleeding. The most common finding of gastroscopy was atrophic gastritis (36%) while early gastric cancer was detected in 2 patients. The most common finding of colonoscopy was colon polyps (42%) while colorectal cancer was detected in 5 patients. Of 180 FIT-positive patients receiving endoscopy, 8 (4.4%) underwent preoperative GI treatment, while postoperative GI events were documented in 28 (15.6%). Of 1,436 with negative FIT, 21 (1.5%) presented GI complications after surgery. Conclusion Preoperative FIT, which is influenced by anticoagulant use, has little impacts on identification of GI bleeding sites. However, it may be useful to detect GI malignant lesions, potentially impacting operative risks, surgical strategies, and postoperative management.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据