4.3 Article

Synthesis of pyrazolines via 1,3-dipolar cycloaddition reactions

期刊

SYNTHETIC COMMUNICATIONS
卷 53, 期 11, 页码 755-770

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2023.2201455

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1; 3-dipolar cycloaddition; Huisgen zwitter ion; nitrile imines; pyrazolines; synthetic protocols

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In this study, various strategies for the synthesis of pyrazoline using the 1,3-dipolar cycloaddition reactions mechanism were reviewed and classified based on starting materials.
Among the large number of reports published on strategies applicable to the synthesis of pyrazolines and its analogs, The 1,3-dipolar cycloaddition offers a remarkably wide range of utility. Many 1,3-dipolar cycloaddition reactions used for the synthesis of pyrazolines provide better selectivity, eco-friendly, and less expensive chemical processes. In the presented study, we have reviewed various recently adopted strategies for the synthesis of pyrazoline which followed the 1,3-dipolar cycloaddition reactions mechanism and classified them based on starting materials.

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