Invited Commentary: De-escalation of axillary surgery in node-positive breast cancer patients after neoadjuvant therapy

Article Surgery

Diagnostic Accuracy of Radioactive Iodine Seed Placement in the Axilla With Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Node-Positive Breast Cancer

Janine M. Simons et al.

Summary: This prospective diagnostic accuracy trial aimed to determine the feasibility and accuracy of the RISAS procedure for axillary staging after neoadjuvant chemotherapy in patients with initially clinically node-positive breast cancer. Results suggest that the RISAS procedure was the most feasible and accurate less-invasive procedure for axillary staging in this patient population.

JAMA SURGERY (2022)

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Article Surgery

A Prospective, Multicenter Registry Study to Evaluate the Clinical Feasibility of Targeted Axillary Dissection (TAD) in Node-positive Breast Cancer Patients

Sherko Kuemmel et al.

Summary: The study demonstrates the feasibility of TAD in a real-world cohort of breast cancer patients, which is of great importance for the de-escalation of surgical strategies.

ANNALS OF SURGERY (2022)

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Article Oncology

Long-term standard sentinel node biopsy after neoadjuvant treatment in breast cancer: a single institution ten-year follow-up

Sabrina Kahler-Ribeiro-Fontana et al.

Summary: This study evaluated the outcomes of patients undergoing NAT who remained or converted to cN0 and received SNB, showing a high overall survival rate after 10-year follow-up. The use of standard SNB in cN1/2 patients who become cN0 after NAT was deemed acceptable and did not result in worse outcomes.

EJSO (2021)

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Article Oncology