A dicyanisophorone-based probe for dual sensing Zn2+ and Cd2+ by near-infrared fluorescence

Zinc ions (Zn2+) and cadmium ions (Cd2+) are widely present in our production and life, which are closely related to human health and environmental protection. Hence, it is essential to detect their concentrations. Herein, we developed a convenient and reliable small-molecule fluorescent probe based on Schiff base of dicyanisophorone and 2-hydrazinopyridine. This probe can be able to selectively detect Zn2+ and Cd2+, showing the advantages of near-infrared emission (the maximum emission wavelength: 668 nm), good selectivity, high sensitivity (the detection limits: 0.21 mu M and 0.31 mu M, respectively) and rapid response (15 s). It has excellent potential for rapid testing and visual tracking of Zn2+ and Cd2+ in aqueous solution and living cells.

Automated summary

We developed a convenient and reliable small-molecule fluorescent probe based on Schiff base of dicyanisophorone and 2-hydrazinopyridine. This probe can selectively detect Zn2+ and Cd2+, showing near-infrared emission, good selectivity, high sensitivity, and rapid response. It has excellent potential for rapid testing and visual tracking of Zn2+ and Cd2+ in aqueous solution and living cells.