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Biodegradable Polymers for Micro Elastofluidics

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SMALL
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WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.202303435

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biodegradable polymers; flexible and implantable devices; hydrogel bead; liquid bead; liquid marble; micro elastofluidics

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Micro elastofluidics, a new research field that combines characteristics of conventional microfluidics and fluid-structure interactions, holds promise for practical applications requiring direct contact between biological samples and fluid handling systems. Choosing the right material is crucial for the practical use of micro elastofluidics, especially in interaction with biological interfaces and long-term functionality. Biodegradable polymers have been extensively studied for this purpose, as they offer exceptional mechanical elasticity, excellent biocompatibility, and degradation into non-toxic products. This article provides an insightful and systematic review of the utilization of biodegradable polymers in digital and continuous-flow micro elastofluidics.
Micro elastofluidics is an emerging research field that encompasses characteristics of conventional microfluidics and fluid-structure interactions. Micro elastofluidics is expected to enable practical applications, for instance, where direct contact between biological samples and fluid handling systems is required. Besides design optimization, choosing a proper material is critical to the practical use of micro elastofluidics upon interaction with biological interface and after its functional lifetime. Biodegradable polymers are one of the most studied materials for this purpose. Micro elastofluidic devices made of biodegradable polymers possess exceptional mechanical elasticity, excellent bio compatibility, and structural degradability into non-toxic products. This article provides an insightful and systematic review of the utilization of biodegradable polymers in digital and continuous-flow micro elastofluidics.

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