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A Mechanistic Proof-of-concept Clinical Trial With JX-594, a Targeted Multi-mechanistic Oncolytic Poxvirus, in Patients With Metastatic Melanoma
Tae-Ho Hwang et al.
MOLECULAR THERAPY (2011)
Induction and function of virus-specific CD4+T cell responses
Jason K. Whitmire
VIROLOGY (2011)
Treatment of metastatic neuroblastoma with systemic oncolytic virotherapy delivered by autologous mesenchymal stem cells: an exploratory study
J. Garcia-Castro et al.
CANCER GENE THERAPY (2010)
Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma
Reiko Nakai et al.
CANCER SCIENCE (2010)
Two-Stage Phase I Dose-Escalation Study of Intratumoral Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers
Kevin J. Harrington et al.
CLINICAL CANCER RESEARCH (2010)
Phase I/II Study of Oncolytic HSVGM-CSF in Combination with Radiotherapy and Cisplatin in Untreated Stage III/IV Squamous Cell Cancer of the Head and Neck
Kevin J. Harrington et al.
CLINICAL CANCER RESEARCH (2010)
Impact of tumor microenvironment on oncolytic viral therapy
Jeffrey Wojton et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2010)
Reovirus Virotherapy Overrides Tumor Antigen Presentation Evasion and Promotes Protective Antitumor Immunity
Shashi A. Gujar et al.
MOLECULAR CANCER THERAPEUTICS (2010)
A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors
John Nemunaitis et al.
MOLECULAR THERAPY (2010)
Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth
Sonia Guedan et al.
MOLECULAR THERAPY (2010)
Delivering nanomedicine to solid tumors
Rakesh K. Jain et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2010)
A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy
Y. Watanabe et al.
ONCOGENE (2010)
Atomic Structure of Human Adenovirus by Cryo-EM Reveals Interactions Among Protein Networks
Hongrong Liu et al.
SCIENCE (2010)
Tumor-associated macrophages infiltrate plasmacytomas and can serve as cell carriers for oncolytic measles virotherapy of disseminated myeloma
Kah-Whye Peng et al.
AMERICAN JOURNAL OF HEMATOLOGY (2009)
Human Bone Marrow-Derived Mesenchymal Stem Cells for Intravascular Delivery of Oncolytic Adenovirus Delta 24-RGD to Human Gliomas
Raymund L. Yong et al.
CANCER RESEARCH (2009)
A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients
J-L Li et al.
GENE THERAPY (2009)
Activation of NF-kB Pathway by Virus Infection Requires Rb Expression
Maria A. Garcia et al.
PLOS ONE (2009)
Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation
Fabian Benencia et al.
CANCER BIOLOGY & THERAPY (2008)
Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity
Robin J. Prestwich et al.
CLINICAL CANCER RESEARCH (2008)
Synergistic Antitumor Effects of Transarterial Viroembolization for Multifocal Hepatocellular Carcinoma in Rats
Jennifer Altomonte et al.
HEPATOLOGY (2008)
Significant antitumor activity of oncolytic adenovirus expressing human interferon-β for hepatocellular carcinoma
Ling Feng He et al.
JOURNAL OF GENE MEDICINE (2008)
Reovirus activates human dendritic cells to promote innate antitumor immunity
Fiona Errington et al.
JOURNAL OF IMMUNOLOGY (2008)
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial
Byeong-Ho Park et al.
LANCET ONCOLOGY (2008)
Potential contribution of tumor suppressor p53 in the host defense against hepatitis C virus
Narayan Dharel et al.
HEPATOLOGY (2008)
An optimized clinical regimen for the oncolytic virus PV701
Sebastien J. Hotte et al.
CLINICAL CANCER RESEARCH (2007)
History of oncolytic viruses: Genesis to genetic engineering
Elizabeth Kelly et al.
MOLECULAR THERAPY (2007)
A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer
Eric J. Small et al.
MOLECULAR THERAPY (2006)
Cell-type-specific repression of internal ribosome entry site activity by double-stranded RNA-binding protein 76
MK Merrill et al.
JOURNAL OF VIROLOGY (2006)
Targeted therapy for glioblastoma multiforme neoplastic meningitis with intrathecal delivery of an oncolytic recombinant poliovirus
H Ochiai et al.
CLINICAL CANCER RESEARCH (2006)
Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity
J Dilley et al.
CANCER GENE THERAPY (2005)
The crystal structure of coxsackievirus A21 and its interaction with ICAM-1
CA Xiao et al.
STRUCTURE (2005)
Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein
SM Sumida et al.
JOURNAL OF IMMUNOLOGY (2005)
Effect of hypoxia on Ad5 infection, transgene expression and replication
BH Shen et al.
GENE THERAPY (2005)
Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression
T Pipiya et al.
GENE THERAPY (2005)
Intracarotid delivery of oncolytic HSV vector G47Δ to metastatic breast cancer in the brain
R Liu et al.
GENE THERAPY (2005)
An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor
H Kambara et al.
CANCER RESEARCH (2005)
Oncolysis of multifocal hepatocellular carcinoma in the rat liver by hepatic artery infusion of vesicular stomatitis virus
K Shinozaki et al.
MOLECULAR THERAPY (2004)
High CD46 receptor density determines preferential killing of tumor cells by oncolytic measles virus
BD Anderson et al.
CANCER RESEARCH (2004)
An oncolytic measles virus engineered to enter cells through the CD20 antigen
AD Bucheit et al.
MOLECULAR THERAPY (2003)
Albumin binding as a general strategy for improving the pharmacokinetics of proteins
MS Dennis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Phase I trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers
AL Pecora et al.
JOURNAL OF CLINICAL ONCOLOGY (2002)
Delivery of herpes simplex virus vectors through liposome formulation
XP Fu et al.
MOLECULAR THERAPY (2001)
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
C Heise et al.
NATURE MEDICINE (2000)
Toll-like receptors in the induction of the innate immune response
A Aderem et al.
NATURE (2000)
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
DF Stojdl et al.
NATURE MEDICINE (2000)
Role of CD47 as a marker of self on red blood cells
PA Oldenborg et al.
SCIENCE (2000)
Intergeneric poliovirus recombinants for the treatment of malignant glioma
M Gromeier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)