Healthy sleep pattern reduce the risk of cardiovascular disease: A 10-year prospective cohort study

Objective: To identify the association between quantified sleep factors and the incidence of cardiovascular disease (CVD) through a 10-year prospective cohort study.Methods: A total of 45,919 individuals were recruited in this population-based prospective study. The healthy sleep score was constructed by four sleep measures (sleep duration, insomnia symptoms, snoring and daytime sleepiness), which were collected by questionnaire. The hazard ratio (HR) and 95% confi-dence intervals (CIs) were calculated by the multivariate-adjusted Cox proportional hazards model. Restricted cubic spline analysis was used to examine the dose-response relationships between healthy sleep scores and outcomes.Results: During a median follow-up of 10.73 years (interquartile range: 10.08-11.72 years), 10,523 cases of total CVD incidence, 3766 cases of CHD, and 3967 cases of stroke incidence were documented. Our results found that participants who maintained four healthy sleep measures (including no insomnia, snoring, or frequent daytime sleepiness and sleeping 7-8 h/d) had a 12% (HR: 0.88, 95% CI: 0.84-0.93) and 16% (HR: 0.84, 95% CI: 0.78-0.92) lower risk of developing CVD and CHD, respectively, but not stroke. There was a dose-response relationship between sleep scores and the risk of cardiovascular events. With an increasing healthy sleep score, the risk of cardiovascular events decreases. Compared to those with a sleep score of 0-1, participants with a score of 4 had 27% (HR: 0.73, 95% CI: 0.67-0.79), 25% (HR: 0.75, 95% CI: 0.65-0.87), and 24% (HR: 0.76, 95% CI: 0.66-0.86) reduced risks of CVD, CHD, and stroke, respectively.Conclusions: In this large prospective cohort study, a healthy sleep pattern effectively reduced the risk of CVD, CHD, and stroke.& COPY; 2023 Elsevier B.V. All rights reserved.

Automated summary

This 10-year prospective cohort study aimed to examine the association between quantified sleep factors and the incidence of cardiovascular disease (CVD). A total of 45,919 individuals were included in the study, and their sleep measures were collected through a questionnaire. The results showed that maintaining healthy sleep measures was associated with a lower risk of developing CVD and CHD, but not stroke. There was a dose-response relationship between sleep scores and the risk of cardiovascular events.