4.6 Article

Sympathetic dysregulation induced by postnatal intermittent hypoxia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Neurosciences

Advancing respiratory-cardiovascular physiology with the working heart-brainstem preparation over 25 years

Julian F. R. Paton et al.

Summary: This review article discusses the progress and potential future applications of the working heart-brainstem preparation (WHBP) in cardiovascular, neuroendocrine, autonomic and respiratory research. The WHBP is a novel in situ experimental model that provides unprecedented access and stability for studying physiological mechanisms. It has revealed new insights into various mechanisms related to respiratory rhythms, sympathetic activity, coupling between respiration and the heart, control mechanisms in the hypothalamus and spinal cord, and chemoreceptor mechanisms. These findings have been validated in vivo and have translated to humans. The article also discusses potential future applications of the WHBP, such as two-photon imaging and pharmacogenetic tools, for improving our understanding and treatment of cardiorespiratory diseases.

JOURNAL OF PHYSIOLOGY-LONDON (2022)

Article Pediatrics

Obstructive Sleep Apnea in Neonates

Indira Chandrasekar et al.

Summary: Neonatal obstructive sleep apnea (OSA) is a common but under-recognized condition that can have significant impacts on growth, development, and even life-threatening cardiovascular morbidity. Diagnosis requires polysomnography and direct visualization of the airway, and treatment should be tailored to the severity of OSA and associated co-morbidities.

CHILDREN-BASEL (2022)

Review Clinical Neurology

Level of urinary catecholamine in children with Sleep Disordered Breathing: A systematic review and meta-analysis

Esther T. W. Cheng et al.

Summary: This study compared the levels of urinary catecholamines in pediatric patients with and without sleep-disordered breathing (SDB). The results showed that patients with SDB and obstructive sleep apnea (OSA) had higher levels of urinary noradrenaline and adrenaline, while urinary dopamine was not associated with SDB. These findings suggest that noradrenaline and adrenaline may serve as markers of sympathetic overtone in patients with SDB and could potentially be used as surrogate markers for SDB complications.

SLEEP MEDICINE (2022)

Article Neurosciences

The relationship between intermittent hypoxemia events and neural outcomes in neonates

Juliann M. Di Fiore et al.

Summary: Intermittent hypoxemia events are common in extremely preterm infants and have been associated with a range of poor neural outcomes. While exposure to some intermittent hypoxia patterns can induce pathophysiological processes, not all patterns are harmful and some may even improve neurodevelopmental outcomes. The goal of therapeutic interventions is to enhance clinical care by implementing targeted interventions for high-risk patterns.

EXPERIMENTAL NEUROLOGY (2021)

Article Cardiac & Cardiovascular Systems

Sleep-Disordered Breathing and Cardiovascular Disease in Children and Adolescents A Scientific Statement From the American Heart Association

Carissa M. Baker-Smith et al.

Summary: Obstructive sleep apnea (OSA) is a well-known risk factor for cardiovascular disease in adults, but its impact on children and adolescents has been less studied. This scientific statement summarizes the effects of OSA on cardiovascular health in young individuals, highlighting key research findings and best practices for diagnosis and evaluation of related complications. It also suggests potential areas for future research in the field of sleep-disordered breathing and cardiovascular health during childhood and adolescence.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)

Review Urology & Nephrology

The global epidemiology of hypertension

Katherine T. Mills et al.

NATURE REVIEWS NEPHROLOGY (2020)

Review Peripheral Vascular Disease

Neuronal Networks in Hypertension Recent Advances

Patrice G. Guyenet et al.

HYPERTENSION (2020)

Article Neurosciences

Inhibitory control of active expiration by the Botzinger complex in rats

Karine C. Flor et al.

JOURNAL OF PHYSIOLOGY-LONDON (2020)

Article Multidisciplinary Sciences

Critical period regulation across multiple timescales

Rebecca K. Reh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Clinical Neurology

Sleep and the Cardiovascular System in Children

Grace R. Paul et al.

SLEEP MEDICINE CLINICS (2017)

Article Cell Biology

Excessive Respiratory Modulation of Blood Pressure Triggers Hypertension

Clement Menuet et al.

CELL METABOLISM (2017)

Article Otorhinolaryngology

Pediatric Obstructive Sleep Apnea

Zarmina Ehsan et al.

OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA (2016)

Article Neurosciences

Essential role of RVL medullary neuronal activity in the long term maintenance of hypertension in conscious SHR

Vera Geraldes et al.

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2014)

Review Clinical Neurology

Does treatment of SDB in children improve cardiovascular outcome?

Anna Vlahandonis et al.

SLEEP MEDICINE REVIEWS (2013)

Article Multidisciplinary Sciences

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension

Fiona D. McBryde et al.

NATURE COMMUNICATIONS (2013)

Article Multidisciplinary Sciences

Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis

Jayasri Nanduri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Medicine, General & Internal

Essential hypertension

Franz H. Messerli et al.

LANCET (2007)

Review Multidisciplinary Sciences

Phenotypic plasticity and the epigenetics of human disease

Andrew P. Feinberg

NATURE (2007)

Review Pharmacology & Pharmacy

Hypoxia-inducible factor-1 (HIF-1)

Qingdong Ke et al.

MOLECULAR PHARMACOLOGY (2006)

Review Neurosciences

The sympathetic control of blood pressure

PG Guyenet

NATURE REVIEWS NEUROSCIENCE (2006)

Article Cardiac & Cardiovascular Systems

Postnatal intermittent hypoxia alters baroreflex function in adult rats

GK Soukhova-O'Hara et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)

Review Peripheral Vascular Disease

Neurogenic essential hypertension revisited: The case for increased clinical and research attention

SJ Mann

AMERICAN JOURNAL OF HYPERTENSION (2003)

Article Multidisciplinary Sciences

Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: Implications for recurrent apneas

YJ Peng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Neurosciences

Modulatory effects of respiration

L Bernardi et al.

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2001)