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Article
Environmental Sciences
Beatrice Daleiden et al.
Summary: Wastewater-based epidemiology (WBE) is an effective method for tracking the spatial distribution and temporal trends of SARS-CoV-2 at the community level. The wastewater monitoring program in Tyrol, Austria has provided valuable insights into the pandemic situation and fulfilled important tasks.
JOURNAL OF WATER AND HEALTH
(2022)
Article
Environmental Sciences
R. Markt et al.
Summary: Utilizing wastewater samples, this study found a correlation between viral load in wastewater and the incidence of COVID-19 cases, and suggested that the emergence of new virus variants may alter the wastewater signal, which should be taken into consideration in future models.
JOURNAL OF WATER AND HEALTH
(2022)
Article
Environmental Sciences
Aikaterini Galani et al.
Summary: This study in Greece measured the SARS-CoV-2 RNA load in raw wastewater as an early indicator of COVID-19 cases, hospitalizations, and ICU admissions, showing predictive leads of 5 to 9 days. Modeling techniques were used to establish relationships between RNA load in wastewater and pandemic health indicators, demonstrating the potential of combining clinical and environmental surveillance data to study and predict COVID-19 dynamics.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Infectious Diseases
Darius Mostaghimi et al.
Summary: As more people receive the SARS-CoV-2 vaccine worldwide, data is being generated to understand the vaccines' ability to reduce infection. Although randomized trials have shown that these vaccines greatly reduce symptomatic COVID-19, their effects on transmission between individuals are not well-known. This article discusses the available data on approved SARS-CoV-2 vaccines in reducing transmissibility by reducing primary infection, viral replication, transmission capacity, and symptomaticity. It also explores the potential of mucosal-targeted vaccine strategies to more effectively limit transmission compared to intramuscular vaccines. The population-level effects of approved vaccines on transmission are further examined through observational studies following clinical trials and vaccine distribution in real-world settings.
LANCET INFECTIOUS DISEASES
(2022)
Article
Biotechnology & Applied Microbiology
Fabian Amman et al.
Summary: Wastewater surveillance of SARS-CoV-2 at the national scale is effective in tracking emerging variants. The study developed a system called VaQuERo, which allows for accurate quantification of predefined variants in complex wastewater samples. The research also identified increased viral genetic diversity during the Delta variant period and proposed a framework for predicting emerging variants and measuring the reproductive advantage of variants of concern using wastewater data.
NATURE BIOTECHNOLOGY
(2022)
Review
Environmental Sciences
Yifan Zhu et al.
Summary: Wastewater-based epidemiology (WBE) is an important tool in the early warning system for COVID-19 pandemic, with the shedding dynamics of infected individuals and back-calculation of observed viral load being major bottlenecks. Optimal sampling strategy is crucial for the success of WBE projects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Chemistry, Analytical
Yolanda Pico et al.
Summary: Wastewater-based epidemiology is not only used to estimate drug abuse and CoVID 19 incidence, but also to establish a fingerprint of city characteristics, such as health status, lifestyle, and exposure to pollutants. By identifying human biomarkers and wastewater characteristics, a better understanding of city features and differences can be achieved.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Psychology, Biological
Thomas Hale et al.
Summary: The Oxford COVID-19 Government Response Tracker (OxCGRT) records data on 19 different government COVID-19 policy indicators for over 190 countries. Covering closure and containment, health and economics measures, it creates an evidence base for effective responses.
NATURE HUMAN BEHAVIOUR
(2021)
Article
Environmental Sciences
Parisa Aberi et al.
Summary: Wastewater-based epidemiology is a valuable source of information for pandemic management, as shown in this study comparing SARS-CoV-2 signal derived from wastewater sampling with COVID-19 incidence values from individual testing programs. The study highlights that data pre-processing and multivariate model formulation are more crucial than the structure of the model for predicting viral incidence based on wastewater data.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Infectious Diseases
Bindu Vekaria et al.
Summary: Predicting hospital length of stay (LoS) for COVID-19 patients is crucial for epidemic planning. This study demonstrates the utility of AFT, TC, and MS methods for predicting LoS using national- and hospital-level data, showing similar overall estimates but significant differences when considering ICU admissions. Multiple analysis methods on different datasets should be used, as each method has its own strengths and limitations.
BMC INFECTIOUS DISEASES
(2021)
Article
Engineering, Environmental
Scott W. Olesen et al.
Summary: The concentration of SARS-CoV-2 in wastewater could serve as a leading indicator of COVID-19 prevalence, but its significance varies depending on the specific application. The quantification of a leading indicator is influenced by epidemiological, biological, and health systems factors.
Article
Engineering, Environmental
Lian Lundy et al.
Summary: The discovery of SARS-CoV-2 RNA in wastewater in early 2020 has led to increased research on wastewater surveillance for COVID-19 mitigation. The NORMAN SCORE database serves as a platform for rapid and open access data sharing, supporting public health decision-making.
Article
Engineering, Environmental
Kyle Bibby et al.
Summary: Wastewater-based epidemiology (WBE) is a valuable tool for tracking and containing COVID-19 spread, with potential for early warning, but delays in analysis and reporting should be considered for a full assessment of its potential. Analysis suggests a potential lead time of four days for WBE in community-level wastewater surveillance, increasing in settings with limited clinical testing capacity.
Article
Engineering, Environmental
Rezgar Arabzadeh et al.
Summary: In SARS-CoV-2 pandemic management, wastewater-based epidemiology aims to monitor virus concentrations in wastewater to derive infection dynamics information. Due to random fluctuations in viral signals caused by various factors, data filtering techniques are helpful in reducing noise for more accurate prevalence analysis. Thirteen smoothing algorithms applied to virus signals in Austrian wastewater treatment plants have shown that SPLINE, Generalized Additive Model, and Friedman's Super Smoother are superior methods, with the latter two possibly over-smoothing.
WATER SCIENCE AND TECHNOLOGY
(2021)
Article
Psychology, Biological
Anna Petherick et al.
Summary: During the COVID-19 pandemic, adherence to physical distancing decreased globally from March to December 2020, while mask-wearing adherence increased. Concerns over 'pandemic fatigue' have been raised as the pandemic continues. The study examined changes in adherence to protective behaviors against COVID-19, showing meaningful and geographically widespread shifts in adherence levels.
NATURE HUMAN BEHAVIOUR
(2021)
Article
Engineering, Environmental
Hannah D. Greenwald et al.
Summary: Wastewater surveillance can be used to detect SARS-CoV-2 RNA, with reliable detection when daily new COVID-19 cases exceed 2.4 per 100,000 people. Evaluation of normalization biomarkers found crAssphage to have the least spatial and temporal variability. Trends in wastewater surveillance data reflect trends in COVID-19 disease occurrence.
Review
Infectious Diseases
Muge Cevik et al.
Summary: This study aimed to characterize the viral load dynamics, duration of viral shedding, and viable virus shedding of SARS-CoV-2 in various body fluids. The findings suggest that while SARS-CoV-2 RNA shedding can be prolonged in respiratory and stool samples, the duration of viable virus shedding is relatively short-lived.
Review
Environmental Sciences
Masaaki Kitajima et al.
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Engineering, Environmental
Gertjan Medema et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2020)
Article
Multidisciplinary Sciences
Roman Woelfel et al.
Article
Biochemistry & Molecular Biology
Xi He et al.
Letter
Gastroenterology & Hepatology
Willemijn Lodder et al.
LANCET GASTROENTEROLOGY & HEPATOLOGY
(2020)
Article
Environmental Sciences
Warish Ahmed et al.
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Environmental Sciences
Olga E. Hart et al.
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Biotechnology & Applied Microbiology
Jordan Peccia et al.
NATURE BIOTECHNOLOGY
(2020)
Letter
Medicine, General & Internal
Anne L. Wyllie et al.
NEW ENGLAND JOURNAL OF MEDICINE
(2020)
Review
Environmental Sciences
Christian G. Daughton
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Environmental Sciences
Giuseppina La Rosa et al.
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Engineering, Environmental
Janelle R. Thompson et al.
