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Preventative Care in Scleroderma What Is the Best Approach to Vaccination?

期刊

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
卷 49, 期 2, 页码 401-410

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W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.rdc.2023.01.012

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Systemic sclerosis; Scleroderma; Vaccination; Vaccines; SARS-CoV-2; Prevention; Preventative medicine

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There are complications associated with SSc that can be prevented or reduced through proper screening and treatment, such as preventing infections with routine vaccinations. Patients with SSc may experience decreased seroconversion due to immunosuppressants, and temporary DMARD suspension may be necessary for vaccinations. Additionally, a prime-boost approach to influenza vaccination may benefit patients.
There are some complications associated with SSc that can be prevented or attenu-ated with appropriate screening and treatment, which may not be consistently per-formed such as preventing infections with routine vaccinations. Patients with SSc can be at risk of decreased seroconversion due to immunosuppressants, and tempo-rary DMARD suspension around vaccinations may be warranted. In addition, patients may benefit from the prime-boost approach to influenza vaccination.

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