相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Metabolite discovery: Biochemistry's scientific driver
Martin Giera et al.
CELL METABOLISM (2022)
HMDB 5.0: the Human Metabolome Database for 2022
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2022)
Metabolomic selection for enhanced fruit flavor
Vincent Colantonio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
The Earth BioGenome Project 2020: Starting the clock
Harris A. Lewin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
Systems metabolic engineering of Streptomyces venezuelae for the enhanced production of pikromycin
Min Kyung Cho et al.
BIOTECHNOLOGY AND BIOENGINEERING (2022)
Diversity: current and prospective secondary metabolites for nutrition and medicine
Nese Sreenivasulu et al.
CURRENT OPINION IN BIOTECHNOLOGY (2022)
Metabolomic selection-based machine learning improves fruit taste prediction
Alisdair R. Fernie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
Predictive evolution of metabolic phenotypes using model-designed environments
Paula Jouhten et al.
MOLECULAR SYSTEMS BIOLOGY (2022)
Single cell metabolism: current and future trends
Ahmed Ali et al.
METABOLOMICS (2022)
AI/ML-driven advances in untargeted metabolomics and exposomics for biomedical applications
Lauren M. Petrick et al.
CELL REPORTS PHYSICAL SCIENCE (2022)
Simultaneous Raman and infrared spectroscopy: a novel combination for studying bacterial infections at the single cell level
Cassio Lima et al.
CHEMICAL SCIENCE (2022)
Image to insight: exploring natural products through mass spectrometry imaging
Yonghui Dong et al.
NATURAL PRODUCT REPORTS (2022)
Deep learning meets metabolomics: a methodological perspective
Partho Sen et al.
BRIEFINGS IN BIOINFORMATICS (2021)
Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra
Kai Duehrkop et al.
NATURE BIOTECHNOLOGY (2021)
NPClassifier: A Deep Neural Network-Based Structural Classification Tool for Natural Products
Hyun Woo Kim et al.
JOURNAL OF NATURAL PRODUCTS (2021)
Domestication of Crop Metabolomes: Desired and Unintended Consequences
Saleh Alseekh et al.
TRENDS IN PLANT SCIENCE (2021)
MassGenie: A Transformer-Based Deep Learning Method for Identifying Small Molecules from Their Mass Spectra
Aditya Divyakant Shrivastava et al.
BIOMOLECULES (2021)
Ultra-high-performance liquid chromatography high-resolution mass spectrometry variants for metabolomics research
Leonardo Perez de Souza et al.
NATURE METHODS (2021)
Conservation of metabolic regulation by phosphorylation and non-covalent small-molecule interactions
Christoph H. Gruber et al.
CELL SYSTEMS (2021)
Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine
Almut Heinken et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 75, 2021 (2021)
Genome-wide association studies: assessing trait characteristics in model and crop plants
Saleh Alseekh et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2021)
Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices
Saleh Alseekh et al.
NATURE METHODS (2021)
Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila
Oliver Gericke et al.
PLANT JOURNAL (2021)
Genomic basis underlying the metabolome-mediated drought adaptation of maize
Fei Zhang et al.
GENOME BIOLOGY (2021)
Metabolomics and complementary techniques to investigate the plant phytochemical cosmos
Hiroshi Tsugawa et al.
NATURAL PRODUCT REPORTS (2021)
Discrimination of bacteria using whole organism fingerprinting: the utility of modern physicochemical techniques for bacterial typing
Najla AlMasoud et al.
ANALYST (2021)
Auto-deconvolution and molecular networking of gas chromatography-mass spectrometry data
Alexander A. Aksenov et al.
NATURE BIOTECHNOLOGY (2021)
Deep Learning to Generate in Silico Chemical Property Libraries and Candidate Molecules for Small Molecule Identification in Complex Samples
Sean M. Colby et al.
ANALYTICAL CHEMISTRY (2020)
Modeling Plant Metabolism: From Network Reconstruction to Mechanistic Models
Teresa J. Clark et al.
ANNUAL REVIEW OF PLANT BIOLOGY, VOL 71, 2020 (2020)
Exploiting Natural Variation in Tomato to Define Pathway Structure and Metabolic Regulation of Fruit Polyphenolics in the Lycopersicum Complex
Takayuki Tohge et al.
MOLECULAR PLANT (2020)
Plant terpenoid metabolism co-opts a component of the cell wall biosynthesis machinery
Adam Jozwiak et al.
NATURE CHEMICAL BIOLOGY (2020)
Machine Learning Applications for Mass Spectrometry-Based Metabolomics
Ulf W. Liebal et al.
METABOLITES (2020)
A lipidome atlas in MS-DIAL 4
Hiroshi Tsugawa et al.
NATURE BIOTECHNOLOGY (2020)
Analysis of wild tomato introgression lines elucidates the genetic basis of transcriptome and metabolome variation underlying fruit traits and pathogen response
Jedrzej Szymanski et al.
NATURE GENETICS (2020)
Feature-based molecular networking in the GNPS analysis environment
Louis-Felix Nothias et al.
NATURE METHODS (2020)
The unmapped chemical complexity of our diet
Albert-Laszlo Barabasi et al.
NATURE FOOD (2020)
Nature's Chemists: The Discovery and Engineering of Phytochemical Biosynthesis
Kaouthar Eljounaidi et al.
FRONTIERS IN CHEMISTRY (2020)
Linking genomics and metabolomics to chart specialized metabolic diversity
Justin J. J. van Der Hooft et al.
CHEMICAL SOCIETY REVIEWS (2020)
Deep metabolome: Applications of deep learning in metabolomics
Yotsawat Pomyen et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2020)
Metabolic GWAS-based dissection of genetic bases underlying the diversity of plant metabolism
Chuanying Fang et al.
PLANT JOURNAL (2019)
A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms
Hiroshi Tsugawa et al.
NATURE METHODS (2019)
Predicting Ion Mobility Collision Cross-Sections Using a Deep Neural Network: DeepCCS
Pier-Luc Plante et al.
ANALYTICAL CHEMISTRY (2019)
A role for plant science in underpinning the objective of global nutritional security?
Cathie Martin
ANNALS OF BOTANY (2018)
Rewiring of the Fruit Metabolome in Tomato Breeding
Guangtao Zhu et al.
CELL (2018)
Quantitative Trait Loci Analysis Identifies a Prominent Gene Involved in the Production of Fatty Acid-Derived Flavor Volatiles in Tomato
Karolina Garbowicz et al.
MOLECULAR PLANT (2018)
From genomics to metabolomics, moving toward an integrated strategy for the discovery of fungal secondary metabolites
T. Hautbergue et al.
NATURAL PRODUCT REPORTS (2018)
Integrative omics for health and disease
Konrad J. Karczewski et al.
NATURE REVIEWS GENETICS (2018)
Metabolomics 20years on: what have we learned and what hurdles remain?
Saleh Alseekh et al.
PLANT JOURNAL (2018)
Machine Learning Predicts the Yeast Metabolome from the Quantitative Proteome of Kinase Knockouts
Aleksej Zelezniak et al.
CELL SYSTEMS (2018)
A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions
Marina Liso et al.
NUTRIENTS (2018)
RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor
Hao Wang et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
YMDB 2.0: a significantly expanded version of the yeast metabolome database
Miguel Ramirez-Gaona et al.
NUCLEIC ACIDS RESEARCH (2017)
Genomewide landscape of gene-metabolome associations in Escherichia coli
Tobias Fuhrer et al.
MOLECULAR SYSTEMS BIOLOGY (2017)
The 3D OrbiSIMS-label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power
Melissa K. Passarelli et al.
NATURE METHODS (2017)
Integrated omics analysis of specialized metabolism in medicinal plants
Amit Rai et al.
PLANT JOURNAL (2017)
Engineering central metabolism - a grand challenge for plant biologists
Lee J. Sweetlove et al.
PLANT JOURNAL (2017)
PLANT SCIENCE A chemical genetic roadmap to improved tomato flavor
Denise Tieman et al.
SCIENCE (2017)
ECMDB 2.0: A richer resource for understanding the biochemistry of E. coli
Tanvir Sajed et al.
NUCLEIC ACIDS RESEARCH (2016)
Functional Metabolomics Describes the Yeast Biosynthetic Regulome
Michael Mulleder et al.
CELL (2016)
Evolutionary Metabolomics Reveals Domestication-Associated Changes in Tetraploid Wheat Kernels
Romina Beleggia et al.
MOLECULAR BIOLOGY AND EVOLUTION (2016)
Omic Relief for the Biotically Stressed: Metabolomics of Plant Biotic Interactions
Hezi Tenenboim et al.
TRENDS IN PLANT SCIENCE (2016)
The WEIZMASS spectral library for high-confidence metabolite identification
Nir Shahaf et al.
NATURE COMMUNICATIONS (2016)
A tutorial review: Metabolomics and partial least squares-discriminant analysis - a marriage of convenience or a shotgun wedding
Piotr S. Gromski et al.
ANALYTICA CHIMICA ACTA (2015)
Focus Issue on Metabolism: Metabolites, Metabolites Everywhere
Alisdair R. Fernie et al.
PLANT PHYSIOLOGY (2015)
Genetic Basis of Metabolome Variation in Yeast
Jeffrey S. Breunig et al.
PLOS GENETICS (2014)
ECMDB: The E-coli Metabolome Database
An Chi Guo et al.
NUCLEIC ACIDS RESEARCH (2013)
The use of metabolomics to dissect plant responses to abiotic stresses
Toshihiro Obata et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection
George Nicholson et al.
PLOS GENETICS (2011)
Resistive Glass IM-TOFMS
Kimberly Kaplan et al.
ANALYTICAL CHEMISTRY (2010)
Metabolomics for Functional Genomics, Systems Biology, and Biotechnology
Kazuki Saito et al.
ANNUAL REVIEW OF PLANT BIOLOGY, VOL 61 (2010)
Application of Fourier-transform ion cyclotron resonance mass spectrometry to metabolic profiling and metabolite identification
Daisaku Ohta et al.
CURRENT OPINION IN BIOTECHNOLOGY (2010)
MassBank: a public repository for sharing mass spectral data for life sciences
Hisayuki Horai et al.
JOURNAL OF MASS SPECTROMETRY (2010)
Combining genetic diversity, informatics and metabolomics to facilitate annotation of plant gene function
Takayuki Tohge et al.
NATURE PROTOCOLS (2010)
The Complex Genetic Architecture of the Metabolome
Eva K. F. Chan et al.
PLOS GENETICS (2010)
Metabolomics, a novel tool for studies of nutrition, metabolism and lipid dysfunction
M. Oresic
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2009)
Global metabolic profiling of Escherichia coli cultures:: An evaluation of methods for quenching and extraction of intracellular metabolites
Catherine L. Winder et al.
ANALYTICAL CHEMISTRY (2008)
The impact of Arabidopsis on human health:: Diversifying our portfolio
Alan M. Jones et al.
CELL (2008)
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors
Eugenio Butelli et al.
NATURE BIOTECHNOLOGY (2008)
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
Markus J. Herrgard et al.
NATURE BIOTECHNOLOGY (2008)
Metabolome analysis of Biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in arabidopsis
Christoph Boettcher et al.
PLANT PHYSIOLOGY (2008)
Proposed minimum reporting standards for chemical analysis
Lloyd W. Sumner et al.
METABOLOMICS (2007)
Multiple high-throughput analyses monitor the response of E-coli to perturbations
Nobuyoshi Ishii et al.
SCIENCE (2007)
The metabolic signature related to high plant growth rate in Arabidopsis thaliana
Rhonda C. Meyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Metabolomics of a superorganism
Royston Goodacre
JOURNAL OF NUTRITION (2007)
The genetics of plant metabolism
Joost J. B. Keurentjes et al.
NATURE GENETICS (2006)
Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement
N Schauer et al.
NATURE BIOTECHNOLOGY (2006)
UPLC/MSE; a new approach for generating molecular fragment information for biomarker structure elucidation
Robert S. Plumb et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2006)
GMD@CSB.DB:: the Golm Metabolome Database
J Kopka et al.
BIOINFORMATICS (2005)
Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor
T Tohge et al.
PLANT JOURNAL (2005)
The Orbitrap: a new mass spectrometer
QZ Hu et al.
JOURNAL OF MASS SPECTROMETRY (2005)
Genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula
L Achnine et al.
PLANT JOURNAL (2005)
GC-MS libraries for the rapid identification of metabolites in complex biological samples
N Schauer et al.
FEBS LETTERS (2005)
UPLC (TM): An introduction and review
ME Swartz
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES (2005)
Discrimination of pathogenic clinical isolates and laboratory strains of Bacillus cereus by NMR-based metabolomic profiling
JG Bundy et al.
FEMS MICROBIOLOGY LETTERS (2005)
Innovation - Metabolite profiling: from diagnostics to systems biology
AR Fernie et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana
MY Hirai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species
A Aharoni et al.
PLANT CELL (2004)
A structure-based anatomy of the E-coli metabolome
I Nobeli et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Parallel analysis of transcript and metabolic profiles: a new approach in systems biology
E Urbanczyk-Wochniak et al.
EMBO REPORTS (2003)
Functional genomics via metabolic footprinting:: monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry
NN Kaderbhai et al.
COMPARATIVE AND FUNCTIONAL GENOMICS (2003)
High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
J Allen et al.
NATURE BIOTECHNOLOGY (2003)
Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics
NJC Bailey et al.
PHYTOCHEMISTRY (2003)
Metabolic flux profiling of Escherichia coli mutants in central carbon metabolism using GC-MS
E Fischer et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics
VV Tolstikov et al.
ANALYTICAL CHEMISTRY (2003)
Extreme pathway lengths and reaction participation in genome-scale metabolic networks
JA Papin et al.
GENOME RESEARCH (2002)
Metabolic profiling of genetic disorders:: A multitissue 1H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue
JL Griffin et al.
ANALYTICAL BIOCHEMISTRY (2001)
Gene discovery via metabolic profiling
RN Trethewey
CURRENT OPINION IN BIOTECHNOLOGY (2001)
Metabolic profiling allows comprehensive phenotyping of genetically or environmentally modified plant systems
U Roessner et al.
PLANT CELL (2001)
A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
LM Raamsdonk et al.
NATURE BIOTECHNOLOGY (2001)
Metabolite profiling for plant functional genomics
O Fiehn et al.
NATURE BIOTECHNOLOGY (2000)