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Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma
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STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy
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STEEP mediates STING ER exit and activation of signaling
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The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κ2B signaling and STING's dual role during MCMV infection
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STING-associated lung disease in mice relies on T cells but not type I interferon
Hella Luksch et al.
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STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death
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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
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Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer
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STIM1 moonlights as an anchor for STING
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Cisplatin-induced immune modulation in ovarian cancer mouse models with distinct inflammation profiles
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IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression
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Disease-associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling
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Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections
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Signalling strength determines proapoptotic functions of STING
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Ubiquitination of STING at lysine 224 controls IRF3 activation
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JAK inhibition in STING-associated interferonopathy
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Activation of STING requires palmitoylation at the Golgi
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Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
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STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease
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STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
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Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations
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IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
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Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ
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STING is a direct innate immune sensor of cyclic di-GMP
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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
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An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
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