4.6 Article

Identification of two unannotated miRNAs in classic Hodgkin lymphoma cell lines

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Deregulated miRNAs Contribute to Silencing of B-Cell Specific Transcription Factors and Activation of NF-κB in Classical Hodgkin Lymphoma

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Summary: Studies have shown that miRNAs play an important role in classical Hodgkin lymphoma (cHL), leading to the loss of B-cell phenotype and NF-kappa B activation. Furthermore, miRNAs regulate this process by targeting B-cell-related transcription factors and NF-kappa B inhibitors.

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